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Biological Roles of Hepatitis B Viral X Protein in the Viral Replication and Hepatocarcinogenesis
Acta Med Okayama. 2023 Aug;77(4):341-345. doi: 10.18926/AMO/65739.ABSTRACTHepatitis B virus is a pathogenic virus that infects 300 million people worldwide and causes chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Hepatitis B virus encodes four proteins. Among them, the HBx protein plays a central role in the HBV pathogenesis. Because the HBx protein is considered to play a central role in the induction of viral replication and hepatocarcinogenesis, the regulation of its function could be a key factor in the development of new interventions against hepatitis B. In this review, HBx protein-related viral r...
Source: Acta Med Okayama - August 27, 2023 Category: Universities & Medical Training Authors: Motoyuki Otsuka Source Type: research