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Neuro-Ophthalmic Manifestations of HIV Infection.
Discussion: Neuro-ophthalmic consequences of HIV are important to recognize as it is critical to identify underlying neoplastic or infectious diseases which could be amenable to treatment. PMID: 31961200 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - January 23, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Neuro-ophthalmological conditions: Study of the clinical care pathway.
CONCLUSIONS: The review of the clinical care pathway of patients affected by neuro-ophthalmological conditions shows that these pathologies are, on the one hand, often poorly understood, and on the other hand complex, leading to an often significant number of steps for the patient. This also emphasizes the necessity of a care network, specialized and structured to improve the efficiency of this management. Finally, these results demonstrate the existence of a very frequent disability, which may affect all aspects of the patients' lives, highlighting the importance of rehabilitation services and individuals participating in...
Source: Journal Francais d Ophtalmologie - June 12, 2017 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research

Neuro-ophthalmological conditions: Study of the clinical care pathway.
CONCLUSIONS: The review of the clinical care pathway of patients affected by neuro-ophthalmological conditions shows that these pathologies are, on the one hand, often poorly understood, and on the other hand complex, leading to an often significant number of steps for the patient. This also emphasizes the necessity of a care network, specialized and structured to improve the efficiency of this management. Finally, these results demonstrate the existence of a very frequent disability, which may affect all aspects of the patients' lives, highlighting the importance of rehabilitation services and individuals participating in...
Source: Journal Francais d Ophtalmologie - June 19, 2017 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research

Effect of neuro-orthopaedic surgery for spastic equinovarus foot after stroke. A prospective longitudinal study based on a goal-centered approach.
CONCLUSIONS: This study confirms the efficacy of the neuro-orthopaedic surgical treatment of spastic equinovarus foot after stroke to improve walking capacities and to achieve personal goals in the body function and activity/participation domains of the ICF. PMID: 29904043 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - June 14, 2018 Category: Rehabilitation Authors: Deltombe T, Gilliaux M, Peret F, Leeuwerck M, Wautier D, Hanson P, Gustin T Tags: Eur J Phys Rehabil Med Source Type: research

Blood-brain barrier and neuro-AIDS.
Authors: Zhang YL, Ouyang YB, Liu LG, Chen DX Abstract Neuro-AIDS is becoming a major health problem among AIDS patients who experience improved survival under combined antiretroviral therapy (cART). Neuronal injury and loss are the critical issues of neuro-AIDS that need the entry of HIV into the central nervous system (CNS) via peripheral infected monocyte/macrophage carriers or viral direct penetration of blood-brain barrier (BBB). The mechanisms of HIV enhancing BBB permeability and entering CNS and the effect of drug abuse in HIV traffic across BBB are discussed. In addition, the current anti-HIV drugs, althou...
Source: European Review for Medical and Pharmacological Sciences - January 15, 2016 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Currents issues in cardiorespiratory care of patients with post-polio syndrome
Conclusion Only when evaluated and treated promptly, somE patients can obtain the full benefits of the use of respiratory muscles aids as far as quality of life is concerned. RESUMO S índrome pós-polio (SPP) é uma condição que afeta sobreviventes da poliomielite aguda (PAA), anos após a recuperação de um ataque agudo inicial do vírus. Na maioria das vezes, os sobreviventes da polio começam a apresentar nova paresia gradual nos músculos que foram previamente afetados pe la infecção. A incidência real de doenças cardiovasculares (DCV) em indivíduos que sofrem de SPP não é conhecida. Entretanto, há indício...
Source: Arquivos de Neuro-Psiquiatria - July 28, 2016 Category: Neurology Source Type: research

Radiomics in paediatric neuro ‐oncology: A multicentre study on MRI texture analysis
Brain tumours are the most common solid cancers in children in the UK and are the most common cause of cancer deaths in this age group. Despite current advances in MRI, non‐invasive diagnosis of paediatric brain tumours has yet to find its way into routine clinical practice. Radiomics, the high‐throughput extraction and analysis of quantitative image features (e.g. texture), offers potential solutions for tumour characterization and decision support. In the search for diagnostic oncological markers, the primary aim of this work was to study the application of MRI texture analysis (TA) for the classification of paediatr...
Source: NMR in Biomedicine - October 27, 2017 Category: Radiology Authors: Ahmed E. Fetit, Jan Novak, Daniel Rodriguez, Dorothee P. Auer, Christopher A. Clark, Richard G. Grundy, Andrew C. Peet, Theodoros N. Arvanitis Tags: RESEARCH ARTICLE Source Type: research

Decoding PERG: a Neuro-Ophthalmic Retinal Ganglion Cell Function Review
AbstractPurpose of ReviewCurrently, the clinical evaluation of neuro-ophthalmologic diseases is mainly focused on identifying stages where structural or functional damage occurs. Recognition of retinal ganglion cell (RGC) functional patterns as well as monitoring RGC dysfunction can be performed using steady-state pattern electroretinogram (PERG). The analysis of the amplitude and latency shift aids on providing information on early damage or monitoring of the RGC, allowing for prompt clinical intervention and management modification, potentially changing the natural history of the disease. The purpose of this article is t...
Source: Current Ophthalmology Reports - February 13, 2019 Category: Opthalmology Source Type: research

Neurological complications of hepatitis C infections.
Abstract Chronic hepatitis C virus (HCV) infection is a highly prevalent systemic disease, which can cause a variety of neurological complications. The HCV-associated symptoms can be differentiated into central and peripheral nervous systems as well as the musculature. Important pathomechanisms are HCV-associated autoimmunity (e.g. mixed cryoglobulinemia with polyneuropathy) and direct neurotoxic effects of the virus (e.g. HCV-associated cognitive deficits). Distal symmetric polyneuropathies, small fiber neuropathies and cognitive deficits are the most prevalent neurological manifestations. Furthermore, HCV infe...
Source: Der Nervenarzt - September 30, 2020 Category: Neurology Authors: Kleefeld F, Arendt G, Neuen-Jacob E, Maschke M, Husstedt I, Obermann M, Schmidt H, Hahn K, Deutsche Gesellschaft für Neuro-AIDS und Neuro-Infektiologie (DGNANI) Tags: Nervenarzt Source Type: research

Glioblastoma multiforme in patients with human immunodeficiency virus: an integrated review and analysis
ConclusionThe diagnosis of GBM in PLWH is severely underreported in the literature. Despite maximal treatment, OS in this patient population is significantly less than in HIV-negative people. There was a poor prognosis of GBM in PLWH, which is inconsistent with previous reports. Further investigation is required for PLWH and concomitant GBM. Analyses must consider if HAART is maintained in PLWH during GBM treatment.
Source: Journal of Neuro-Oncology - July 20, 2022 Category: Cancer & Oncology Source Type: research

Comparative evaluation of Octopus semi-automated kinetic perimeter with Humphrey and Goldmann perimeters in neuro-ophthalmic disorders
Conclusion: Clinical correlation aids in better characterisation of a field defect. All 3 perimeters are concurrent in the pattern of field defects for non-central defects. However, the default protocol on OVF may not be enough to demarcate the central and para-central scotomas. Development of a customised protocol for the assessment of central and centrocecal field defects increases the accuracy of OVF.
Source: Indian Journal of Ophthalmology - March 16, 2021 Category: Opthalmology Authors: Karthika Bhaskaran Swati Phuljhele Pawan Kumar Rohit Saxena Dewang Angmo Pradeep Sharma Source Type: research

Cryptococcal meningitis in a patient with a ventriculoperitoneal shunt and monitoring for pulmonary sarcoidosis.
We report the case of a patient harboring a ventriculoperitoneal shunt, and having contracted a cryptococcal meningitis as a risk factor for pulmonary sarcoidosis. Brain MRI showed arachnoiditis, with a mass in contact with the right frontal horn. Indian ink staining of the cerebrospinal fluid (CSF) showed positivity that was confirmed by the identification of Cryptococcus neoformans after culture. The evolution was favorable under medical treatment with removal of material. The relationship between sarcoidosis and cryptococcosis, described in the literature is not coincidental but is a rare complication of sarcoidosis of ...
Source: Neuro-Chirurgie - February 7, 2013 Category: Neurosurgery Authors: Baallal H, El Asri AC, Eljebbouri B, Akhaddar A, Gazzaz M, El Mostarchid B, Boucetta M Tags: Neurochirurgie Source Type: research

Internet Search Patterns of Human Immunodeficiency Virus and the Digital Divide in the Russian Federation: Infoveillance Study
Conclusions: This study contributes to the methodological literature on search patterns in public health. Based on our preliminary research, we suggest that PCA may be used to evaluate the relationship between the determinants of Internet access and searches for health problems beyond high-income countries. We believe it is in middle-income countries that search methods can make the greatest contribution to public health.
Source: Journal of Medical Internet Research - November 12, 2013 Category: Journals (General) Authors: Andrey ZhelukCasey QuinnDaniel HerczJames A Gillespie Source Type: research

Delivery of Tenofovir to the Brain by Novel Nano-Vesicles for the Treatment of Neuro-HIV (S10.003)
CONCLUSIONS: V-SmartTM vesicles, optimized for brain delivery of tenofovir, successfully delivered therapeutic amounts of the drug into the brain after a single iv administration. The results indicate the feasibility of using the V-SmartTM vesicles for lowering viral load in the CNS of HIV patients.Study Supported by: The Campbell FoundationDisclosure: Dr. Heldman has received personal compensation for activities with Lauren Sciences. Dr. Heldman has received research support from Lauren Sciences. Dr. Linder has received personal compensation for activities with Lauren Sciences. Dr. Linder has received research support fro...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Heldman, E., Linder, C., Grinberg, S., Popov, M., Hollander, I. Tags: HIV, PML, and Cerebral Malaria Source Type: research