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Janssen Submits New Drug Application to the U.S. Food and Drug Administration Seeking Approval of Niraparib and Abiraterone Acetate Dual-Action Tablet, Plus Prednisone, as a First-Line Targeted Treatment for Patients with Metastatic Castration-Resistant Prostate Cancer with BRCA Gene Mutations
RARITAN, N.J., February 28, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval of niraparib in combination with abiraterone acetate, in the form of a dual-action tablet (DAT), plus prednisone, for the treatment of patients with BRCA-positive metastatic castration-resistant prostate cancer (mCRPC). If approved, this will be the first DAT formulation available in the U.S. to patients with mCRPC with BRCA mutations, which are a type of homologous recombination repair (HRR) gene alt...
Source: Johnson and Johnson - March 1, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
What “off-label” use of a drug really is, and why you need to know about it
When your doctor prescribes a drug for you, you probably assume — and with good reason — that it is an FDA-approved treatment for your condition.
That may or may not be the case.
On average, one in five prescriptions are written for an “off-label” use of a drug. That means your doctor believes that the drug will help you even if it has not been approved specifically for your illness or symptoms.
Off-label prescribing of drugs is legal and common, and can be beneficial for patients. For example, beta blockers (drugs approved to lower blood pressure and treat heart disease) can also help some people with migr...
Source: New Harvard Health Information - September 4, 2015 Category: Consumer Health News Authors: Gregory Curfman, MD Tags: Drugs and Supplements off-label use of a drug Source Type: news
Abstract A42: A community of cancer communicators: The influence of a collaborative faith-based social marketing project to address CRC risk and prevention among African American church populations
African Americans have the highest colorectal cancer (CRC) mortality and morbidity rates when compared to all other racial and ethnic groups in the United States (ACS, 2014). Faith-based health promotion interventions and programs targeting this population have shown effective however cancer disparities remain; in some cases the cancer mortality gap is widening among African American men (Jemal et. al, 2010). Strategic health communication programs that engage and include the consumer in a collaborative communication process can help to address and eventually break down barriers that contribute to health disparities (Kreps...
Source: Cancer Epidemiology Biomarkers and Prevention - April 14, 2016 Category: Cancer & Oncology Authors: Lumpkins, C., Nwachokor, D., Blackstock, A., Blackstock, A., Crawford, B., Miller, L., Groves, I. B. S., Greiner, K. A., Daley, C. Tags: Community-Based Participatory Research: Poster Presentations - Proffered Abstracts Source Type: research
How Price Transparency Caused Patients to Gripe Loudly about the Skyrocketing Cost of Mylan ’s EpiPen and Why Clinical Laboratories Should Watch Next Developments
Medical laboratory managers are getting an important lesson in the power of price transparency to motivate patients to complain about arbitrarily high prices for healthcare services and products By now, most clinical laboratory managers and pathologists know about the EpiPen pricing scandal. Simply said, it illustrates all the flaws and problems in the US healthcare […]
Source: Dark Daily - October 5, 2016 Category: Laboratory Medicine Authors: jude Tags: Laboratory News Laboratory Operations Laboratory Pathology Laboratory Sales and Marketing Laboratory Testing Adrenaline Anaphylaxis Auto-Injectors clinical laboratory Dark Daily dark intelligence group Dark Report Epinephrine Epi Source Type: news
Functional foods in Turkey: marketing, consumer awareness and regulatory aspects
This study provides market study and detailed research about marketing strategies and legislation of functional foods in Turkey. People have high demand to consume and there are big potentials of fun ctional food marketing and opportunities for food industries. But to increase consumption and marketing size, it needs education of consumer, advertising and some adjustment of legislation by government.
Source: Nutrition and Food Science - December 20, 2018 Category: Nutrition Source Type: research
A2A2 milk: Brazilian consumers’ opinions and effect on sensory characteristics of Petit Suisse and Minas cheeses
Publication date: Available online 25 March 2019Source: LWTAuthor(s): Mariana Oliveira Mendes, Murielle Ferreira de Morais, Jéssica Ferreira RodriguesAbstractβ-casein (β-CN) A1 and A2 variants recently been gaining increasing interest from both researchers and consumers, stimulating a new trend in the dairy market. However, there are few reports about the A2 milk usage in dairy manufacturing and consumer perceptions. Thus, this study aimed to assess the effects of the β-CN A2 on sensory characteristics of Petit Suisse and Minas cheeses; and evaluate the Brazilian consumer opinions about A2 products and their market pot...
Source: LWT Food Science and Technology - March 27, 2019 Category: Food Science Source Type: research
IJERPH, Vol. 18, Pages 2381: Old Tricks, New Opportunities: How Companies Violate the International Code of Marketing of Breast-Milk Substitutes and Undermine Maternal and Child Health during the COVID-19 Pandemic
This study identified marketing tactics of BMS companies since the start of the COVID-19 pandemic by reviewing promotional materials and activities from 9 companies in 14 countries, and the official Code reporting data from the Philippines. Eight qualitative themes emerged that indicate companies are capitalizing on fear related to COVID-19 by using health claims and misinformation about breastfeeding. Other promotional tactics such as donations and services were used to harness the public sentiment of hope and solidarity. Past studies show that these tactics are not new, but the pandemic has provided a new entry point, he...
Source: International Journal of Environmental Research and Public Health - March 1, 2021 Category: Environmental Health Authors: Constance Ching Paul Zambrano Tuan T. Nguyen Manisha Tharaney Maurice Gerald Zafimanjaka Roger Mathisen Tags: Article Source Type: research
The medium and the message: comparing the effectiveness of six methods of misinformation delivery in an eyewitness memory paradigm - Greene CM, Bradshaw R, Huston C, Murphy G.
Studies of eyewitness memory commonly employ variations on a standard misinformation paradigm. Participants are (a) exposed to an event (e.g., a simulated crime), (b) misled about certain details of the event and (c) questioned about their memory of the or...
Source: SafetyLit - June 14, 2021 Category: International Medicine & Public Health Tags: Media, Marketing, and Internet Issues Source Type: news
Advancing Your Confidence as an Educator (ACE): An academic-VA partnership to enhance educator skills and improve attitudes about careers in aging.
Previous research suggests some psychologists may not consider academic careers because of doubts about their teaching competency, and this is especially true for psychologists interested in aging (i.e., geropsychologists). To enhance competencies in the practice of education, we developed a webinar series, Advancing Your Confidence as an Educator, to bolster skills and attitudes toward teaching and improve attitudes about careers in aging. Seven hour-long webinars addressed key skills in developing and executing courses and professional presentations, and 2 panel sessions addressed attitudes toward teaching by featuring e...
Source: Training and Education in Professional Psychology - April 9, 2020 Category: Psychiatry & Psychology Source Type: research
Black Community Conversations About Opposing Ethnically Targeted Marketing of Unhealthy Foods and Beverages
AbstractEfforts to reduce disparities in obesity prevalence affecting Black Americans are having limited success. One reason for this may be the disproportionate, ethnically targeted marketing of foods and beverages high in fat and sugar (FBHFS) to Black consumers. Such marketing promotes high consumption of FBHFS, leading to excess caloric intake and unintentional weight gain. We convened focus groups with Black men and women (totaln = 57) in collaboration with community groups in three localities to elicit their views, as consumers and parents/caregivers, about targeted FBHFS marketing and potential ways to combat it...
Source: Journal of Racial and Ethnic Health Disparities - August 20, 2021 Category: International Medicine & Public Health Source Type: research
Drinking Too Much and Feeling Bad About It? How Group Identification Moderates Experiences of Guilt and Shame Following Norm Transgression
The role of reference group norms in self-regulation was examined from the perspective of transgressions. Results from four studies suggest that following the transgression of a reference group’s norms, individuals who strongly identify with their group report more intense feelings of guilt, an emotion reflecting an inference that "bad" behaviors are perceived as the cause of the transgression. Conversely, weakly identified individuals reported more intense feelings of shame, an emotion reflecting an inference that "bad" characteristics of the person are perceived as the cause of the transgression. The studies also e...
Source: Personality and Social Psychology Bulletin - April 10, 2014 Category: Psychiatry & Psychology Authors: Giguere, B., Lalonde, R. N., Taylor, D. M. Tags: Articles Source Type: research
If you were unable to participate in today ’ s CDRH webinar where we reviewed and answered questions about the Marketing Clearance of Diagnostic Ultrasound Systems and Transducers Final Guidance, the transcript and recording will be available on August 30th https://go.usa.gov/xV246
If you were unable to participate in today’s CDRH webinar where we reviewed and answered questions about the Marketing Clearance of Diagnostic Ultrasound Systems and Transducers Final Guidance, the transcript and recording will be available on August 30th https://go.usa.gov/xV246
Source: Food and Drug Adminstration (FDA): CDRHNew - August 22, 2019 Category: Medical Devices Authors: ( at FDADeviceInfo) Source Type: news
Association Between PRRSV ORF5 Genetic Distance and Differences in Space, Time, Ownership and Animal Sources Among Commercial Pig Herds
The objective of this study was to investigate associations between genetic distance of porcine reproductive and respiratory syndrome virus (PRRSV) detected in Ontario swine herds, and the distance between the herds with respect to space, time, ownership and animal sources. PRRSV sequence data between September 2004 and August 2007 were obtained from the Animal Health Laboratory of the University of Guelph. Geographical coordinates were obtained from the Ontario Pork marketing board, and network information about ownership and animal suppliers was obtained using a telephone interview. The matrices of sequence, spatial, tem...
Source: Transboundary and Emerging Diseases - August 1, 2014 Category: Veterinary Research Authors: T. Rosendal, C. Dewey, R. Friendship, S. Wootton, B. Young, Z. Poljak Tags: Original Article Source Type: research
Mind Genomics (Conjoint Analysis): The new concept research in the analysis of consumer behaviour and choice
Publication date: Available online 7 May 2018 Source:Trends in Food Science & Technology Author(s): Sebastiano Porretta, Attila Gere, Dalma Radványi, Howard Moskowitz Concepts are critical for the development and marketing of products and services. Market research practitioners and their corporate clients are well aware of the need to create winning concepts. To that end, a very large practice has emerged in the business world designed to understand the current competitive environment, identify opportunities, and convert these opportunities into concepts. Look at any prospectus by a market research company and th...
Source: Trends in Food Science and Technology - May 8, 2018 Category: Food Science Source Type: research
