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Versatile neuromorphic electronics by modulating synaptic decay of single organic synaptic transistor: From artificial neural networks to neuro-prosthetics
Publication date: November 2019Source: Nano Energy, Volume 65Author(s): Dae-Gyo Seo, Yeongjun Lee, Gyeong-Tak Go, Mingyuan Pei, Sungwoo Jung, Yo Han Jeong, Wanhee Lee, Hea-Lim Park, Sang-Woo Kim, Hoichang Yang, Changduk Yang, Tae-Woo LeeAbstractOrganic neuromorphic electronics are inspired by a biological nervous system. Bio-inspired computing mimics learning and memory in a brain (i.e., the central nervous system), and bio-inspired soft robotics and nervous prosthetics mimics the neural signal transmission of afferent/efferent nerves (i.e., the peripheral nervous system). Synaptic decay time of nerves differ among biologi...
Source: Nano Energy - September 26, 2019 Category: Nanotechnology Source Type: research

Adaptive neuro-fuzzy inference system (ANFIS) and multiple linear regression (MLR) modelling of Cu, Cd, and Pb adsorption onto tropical soils
In this study, we investigated the sorption of Pb, Cd, and Cu in five natural soils of Nigerian origin. A relatively sparsely used method of modelling soil-metal ion adsorption, i.e. adaptive neuro-fuzzy inference system (ANFIS), was applied comparatively with multiple linear regression (MLR) models. The isotherms were well described by Freundlich and Langmuir equations (R2 ≥ 0.95) and the kinetics by nonlinear two-stage kinetic model, TSKM (R2 ≥ 0.81). Based on the values delivered by the Langmuir equation, the maximum adsorption capacities (Qm*) were found to be in the ranges 10,000-20,000, 12,500-50,000, and 4929-35...
Source: Environmental Science and Pollution Research International - November 28, 2022 Category: Environmental Health Authors: Babatunde Kazeem Agbaogun Bamidele Iromidayo Olu-Owolabi Henning Buddenbaum Klaus Fischer Source Type: research

Effects of neuro-immuno-modulation on healing of wound combined with local radiation injury in rats.
CONCLUSION: Level of serous neurohormone GC in rats increased significantly immediately after wound and radiation; while the level of IFN-γ showed significant increase only up to 14 d after wound and radiation, and the Th1/Th2 imbalance sustained till 28 d post wound and radiation. In order to reduce acute damage caused by CWR, organic immune system and nerve system showed up a marked regulate effects simultaneously and mutually. Nonetheless, the excessive stress induced by CWR causes disturbance of immunoregulation, which is one of the key reasons for delayed wound healing in CWR. PMID: 29079271 [PubMed - as supplied by publisher]
Source: Chinese Journal of Traumatology - September 23, 2017 Category: Orthopaedics Authors: Ma Q, Cai JL, Pan XJ, Du L, Yang XY, Liu YX, Zhang QL, Cui YF Tags: Chin J Traumatol Source Type: research

Development of adaptive neuro-fuzzy inference system model for predict trihalomethane formation potential in distribution network simulation test.
Abstract Trihalomethanes (THMs), which is one of the major classes of DBP known to be highly cytotoxic and genotoxic, were formed and modeled under controlled conditions by laboratory-scale distribution network simulation test. The formation potentials of THM depending on the parameters such as natural organic matter, bromide, chlorine, pH, and contact time were determined. Subsequently, the Adaptive Neuro-Fuzzy Inference System (ANFIS) model was developed using these parameters as inputs and THM formation potentials as output, and the correlation coefficient was 0.9817. In the range of the inputs, the ANFIS model...
Source: Environmental Science and Pollution Research International - November 26, 2020 Category: Environmental Health Authors: Alver A, Baştürk E, Kılıç A Tags: Environ Sci Pollut Res Int Source Type: research

Supplementation of Caricol ®-Gastro reduces chronic gastritis disease associated pain.
DISCUSSION: Due to the inherent biological activities of ingredients of papaya and of oats and their known effects (anti-inflammatory, epithelial integrity), the observed beneficial effects may be owed to the constituents synergisms to reduce chronic inflammation. We conclude, that the regular intake is a safe add on therapeutic option for patients with chronic gastritis to support standard medical care. PMID: 29604620 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - April 3, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Using the combined model of gamma test and neuro-fuzzy system for modeling and estimating lead bonds in reservoir sediments.
This study collected 180 samples of the surface sediments of water reservoir 1 at Chahnimeh in Sistan. Efficiency of the ANFIS model was evaluated to estimate the five bonds following the measurement of parameters in the laboratory.The following results were obtained for the parameters: organic carbon (OC) %, 0.31; cation exchange capacity (CEC), 37.07 Cmol kg; total Pb, 25.19 mg/kg; clay %, 45.87; and silt %, 39.02. These parameters were used as input for the training model. In the output layer, lead bonds were chosen as modeling targets in the following way: Pb f1 (4.61); Pb f2 (0.54); Pb f3 (16.28); Pb f4 (3.42); and...
Source: Environmental Science and Pollution Research International - August 29, 2018 Category: Environmental Health Authors: Mohammadi AA, Yousefi M, Soltani J, Ahangar AG, Javan S Tags: Environ Sci Pollut Res Int Source Type: research

Neuroinflammation and aberrant hippocampal plasticity in a mouse model of emotional stress evoked by exposure to ultrasound of alternating frequencies
Publication date: Available online 22 November 2018Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Dmitrii Pavlov, Lucien Bettendorff, Anna Gorlova, Andrey Olkhovik, Allan Kalueff, Eugene Ponomarev, Anatoly Inozemtsev, Vladimir Chekhonin, Klaus-Peter Lesсh, Daniel C. Anthony, Tatyana StrekalovaAbstractEmotional stress is a form of stress evoked by processing negative mental experience rather than an organic or physical disturbance and is a frequent cause of neuropsychiatric pathologies, including depression. Susceptibility to emotional stress is commonly regarded as a human-specific trait ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - November 23, 2018 Category: Psychiatry Source Type: research

Fructose-1,6-bisphosphatase deficiency presented with complex febrile convulsion.
Authors: Abstract Fructose-1,6-bisphosphatase (FBPase) deficiency is a rare inborn error of metabolism affecting gluconeogenesis caused by FBP1 gene mutations. It could be more fatal to infants and children when glycogen reserves are insufficient. A 4-year-old girl was admitted with complex febrile convulsion. Initial laboratory results showed hypoglycemia, metabolic acidosis, and hyperlactatemia. Plasma amino acid and urine organic acid analyses showed increased levels of alanine and tricarboxylic acid cycle intermediates. However, she had similar clinical features, including confusion under severe hypoglycemia,...
Source: Neuroendocrinology Letters - April 1, 2019 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Increased platelet activity in tinnitus patients.
CONCLUSION: Tinnitus patients showed higher levels of increased platelet activity, a marker that may play an important role in the pathogenesis of tinnitus. PMID: 33185996 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - November 18, 2020 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Stereoselective preparation of key intermediates for the synthesis of iso-, neuro- and phyto-prostane family members: Inaugural asymmetric synthesis of 17-E2c-dihomo- and 17-F2c-dihomo-isoprostanes.
Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB00489G, CommunicationAndrea Gandini, Ahmed A Amin, Hawraz Ibrahim M Amin, Davide Corriero, Alessio Porta, Giuseppe Zanoni A practical methodology for the synthesis of a key intermediates for isoprostane, neuroprostane and dihomoisoprostane preparation, has been described. The key strategy involved a three stage C-12 stereocenter epimerization of... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - March 13, 2018 Category: Molecular Biology Authors: Andrea Gandini Source Type: research

Publisher Correction: Controlling an organic synthesis robot with machine learning to search for new reactivity
Publisher Correction: Controlling an organic synthesis robot with machine learning to search for new reactivity, Published online: 24 July 2018; doi:10.1038/s41586-018-0412-8Publisher Correction: Controlling an organic synthesis robot with machine learning to search for new reactivity
Source: Nature AOP - July 24, 2018 Category: Research Authors: Jaros ław M. Granda Liva Donina Vincenza Dragone De-Liang Long Leroy Cronin Source Type: research

Global Minimum Search and Bonding Analysis of Tl2Hx and Tl3Hy (x=0-6; y=0-5) Series
Chemphyschem. 2023 Jun 2:e202300332. doi: 10.1002/cphc.202300332. Online ahead of print.ABSTRACTA remarkable comparison of Boron and Carbon hydrides can be expressed in extremely different bonding patterns and chemical reactivity, which ultimately leads to different areas of applications. Particularly, Carbon, based on classical two-center - two-electron bonds, gives rise to organic chemistry. Oppositely, Boron produces many exotic and somewhat non-intuitive compounds collectively called non-classical structures. It's natural to expect other elements of Group 13 to possess their own unusual bonding patterns; however, our k...
Source: Chemphyschem - June 2, 2023 Category: Chemistry Authors: Anton S Pozdeev Pavel Rublev Alexander I Boldyrev Yi Rao Source Type: research

Identification of novel non-ionic, cationic, zwitterionic, and anionic polyfluoroalkyl substances using UPLC-TOF-MS(E) high-resolution parent ion search.
This study presents a time-of-flight mass spectrometry approach based on continuously interleaving scans at low and high collision energies (ToF-MS(E)) for the rapid identification and characterization of unknown PFASs. The MS(E) mode allowed for the simultaneous acquisition of full-spectrum accurate mass data of both parent and fragment ions in a single chromatographic run. Specific to PFASs, the hypothesis that PFASs can be selectively detected by the ToF-MS(E) high-resolution parent-ion search (HRPIS) of their characteristic fragments was confirmed with certified standards of 24 poly- and per-PFAS. After being validated...
Source: Analytica Chimica Acta - September 18, 2017 Category: Chemistry Authors: Xiao F, Golovko SA, Golovko MY Tags: Anal Chim Acta Source Type: research

Prebiotic Chemistry of HCN Tetramerization by Automated Reaction Search.
We report an explorative study based on automated reaction search method that avoid the cognitive bias in searching the chemical reaction space. We have discussed the chemical space of HCN dimer elaborately, and the important trimers and tetramers are discussed briefly. A component wise molecular fingerprint based methodology is proposed for identifying molecular similarity. Overall, we present four different thermal routes to cis/trans-2,3-diaminomaleonitrile and 4-aminoimidazole-5-carbonitrile, the important intermediates in the prebiotic chemistry. PMID: 29369429 [PubMed - as supplied by publisher]
Source: Chemistry - January 25, 2018 Category: Chemistry Authors: Nandi S, Bhattacharyya D, Anoop A Tags: Chemistry Source Type: research

Search of non-ionic surfactants suitable for micellar liquid chromatography.
Abstract Most reports in reversed-phase liquid chromatography (RPLC) with micellar mobile phases make use of the anionic sodium dodecyl sulfate. This surfactant masks efficiently the silanol groups that are the origin of the poor efficiencies and tailing peaks observed for basic compounds in conventional RPLC. However, it has the handicap of yielding excessive retention, which forces the addition of an organic solvent to reduce the retention times to practical values. Other surfactants, such as the non-ionic polyoxyethylene(23)lauryl ether (Brij-35), are rarely used. Brij-35 allows the separation of a large range ...
Source: Analytical and Bioanalytical Chemistry - June 19, 2018 Category: Chemistry Authors: Peris-García E, Rodríguez-Martínez J, Baeza-Baeza JJ, García-Alvarez-Coque MC, Ruiz-Angel MJ Tags: Anal Bioanal Chem Source Type: research