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Big Data Research in Neuro-Ophthalmology: Promises and Pitfalls
Conclusions: Big data clinical research studies complement other research methodologies to advance our understanding of human disease. A rigorous and careful approach to data set selection, data management, data analysis, and data interpretation characterizes high-quality studies.
Source: Journal of Neuro-Ophthalmology - December 1, 2019 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Hospital teaching status associated with reduced inpatient mortality and perioperative complications in surgical neuro-oncology
ConclusionTHs are performing more brain tumor surgeries over time with lower rates of inpatient mortality and perioperative complications even after controlling for hospital case volume. These results suggest a shift in neuro-oncology practice patterns favoring THs to optimize patient outcomes especially at the highest volume centers.
Source: Journal of Neuro-Oncology - January 13, 2020 Category: Cancer & Oncology Source Type: research

Spaceflight associated neuro-ocular syndrome
Purpose of review Several decades of long duration space flight missions by the National Aeronautics and Space Administration has revealed an interesting and unique constellation of neuro-ophthalmic findings now called spaceflight associated neuro-ocular syndrome (SANS). The unique space environment of microgravity produces novel physiological changes and derangements that present a challenge to astronauts in current and future long duration space missions. Although the precise mechanism of SANS is not fully understood, in this review, we examine recent developments that may to help explain possible causes and potential ...
Source: Current Opinion in Neurology - January 17, 2020 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Heather E. Moss Source Type: research

Editorial: advances in neuro-oncology and clinical treatment —from ASNO 2019
AbstractThe 16th Annual Meeting of the Asian Society for Neuro-Oncology was successfully held in Taipei, September 26 –29. The diverse, in-depth experiences sharing in the conference contributed the fruitful result. Here we selected several important manuscripts to represent the advance of neuro-oncology and clinical treatment in Asia.
Source: Journal of Neuro-Oncology - January 31, 2020 Category: Cancer & Oncology Source Type: research

The 2020 Update to North American Neuro-Ophthalmology Society's (NANOS) Neuro-Ophthalmology Curriculum
No abstract available
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

Orbital disease in neuro-ophthalmology
Purpose of review Orbital disease represents a diverse spectrum of pathology and can result in a variety of neuro-ophthalmic manifestations. The aim of this review is to provide updates on recent advances in our understanding of orbital disease secondary to thyroid eye disease, myositis, IgG4-related disease, sarcoidosis, granulomatosis with polyangiitis and various tumours. Recent findings With regards to thyroid eye disease, there have been recent advances in the development of steroid-sparing therapies, new modalities for objectively monitoring disease activity and increased understanding of the role of environment...
Source: Current Opinion in Ophthalmology - October 3, 2020 Category: Opthalmology Tags: NEURO-OPHTHALMOLOGY: Edited by Dean M. Cestari Source Type: research

Implementation, relevance, and virtual adaptation of neuro-oncological tumor boards during the COVID-19 pandemic: a nationwide provider survey
ConclusionsVirtual implementation of NTBs was feasible and accepted in the centers surveyed. Therefore, successful implementation offers new avenues and may be pursued for networking between centers, thereby increasing coverage of neuro-oncology care.
Source: Journal of Neuro-Oncology - June 11, 2021 Category: Cancer & Oncology Source Type: research

Pattern of technology diffusion in the adoption of stereotactic laser interstitial thermal therapy (LITT) in neuro-oncology
ConclusionFor neuro-oncology indications, LITT utilization increased  ~ 400% relative to craniotomy. Relative to craniotomy-treated patients, LITT-treated patients were likelier to be young, female, non-Black race, covered by private insurance, or with <  2 comorbidities. While the total hospital charges were comparable, LITT was associated with a shorter hospitalization relative to craniotomy.
Source: Journal of Neuro-Oncology - June 13, 2021 Category: Cancer & Oncology Source Type: research

Neuro-Ophthalmic Manifestations of Mollaret Meningitis
We present a case of recurrent HSV-2 meningitis with the neuro-ophthalmic presentation of papilledema and sixth nerve palsy. To our knowledge, this is the first such description in the English language ophthalmic literature.
Source: Journal of Neuro-Ophthalmology - August 28, 2021 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Neuro-Ophthalmologic Monitoring in the Management of Increased Intracranial Pressure From Leaking Arachnoid Cysts
Conclusions: Because constitutional symptoms and even imaging are not always reliable indicators of high ICP in leaking arachnoid cysts, neuro-ophthalmologic monitoring of papilledema is valuable in identifying the cases when neurosurgical intervention is necessary.
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Introducing the 24-2C Visual Field Test in Neuro-Ophthalmology
This study compares the new 24-2C test to the standard Humphrey 10-2 visual field test in patients presenting for neuro-ophthalmology evaluation to evaluate its ability to detect central visual field defects. Methods: Twenty-five neuro-ophthalmology patients (42 eyes) underwent both 24-2C and 10-2 visual field testing using the Humphrey perimeter. The number of flagged total deviation (TD) and pattern deviation (PD) points of the 10 added test points of the 24-2C were compared with the corresponding 10-2 fields at the P
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

No Light Perception Vision in Neuro-Ophthalmology Practice
Conclusions: NLP vision may occur because of various diagnoses. Vision recovery was mainly seen in patients with ON. Serious systemic conditions may present or relapse with NLP vision, which clinicians should consider as an alarming sign in patients with known malignancies.
Source: Journal of Neuro-Ophthalmology - February 25, 2022 Category: Opthalmology Tags: Original Contribution Source Type: research

Insights from a Neuro-Rheumatology Clinic
Neuro-rheumatology is a fast-growing field. Better testing and imaging have increased recognition of once-infrequent diagnoses, such as neuro-sarcoidosis and amyloid beta-related angiitis. Concurrently, the rapid expansion of immunotherapy options to treat cancer and their untoward neurological side effects have increased the frequency of referrals to both neurologists and rheumatologists. Identifying and treating neurologic manifestations of... [Read More]
Source: The Rheumatologist - April 7, 2023 Category: Rheumatology Authors: Kristin Galetta, MD, Shamik Bhattacharyya, MD, & Simon M. Helfgott, MD Tags: Practice Management collaboration Collaboration Initiatives interdisciplinary neuro-rheumatology Neurology Source Type: research

Quantitative and qualitative analysis of study-related patient information sheets in randomised neuro-oncology phase III-trials
Discussion: Quality deficits were consistent between the individual study information texts. Irrespective of formal aspects, a document that is intended to inform and motivate patients to participate in a study needs to be well-structured and understandable. We therefore strongly mandate to re-design patient informed consent documents in a patient-friendly way. Specifically, standardised components with a scientific foundation should be provided that could be retrieved at various times, adapted to the mode of treatment and the patient’s knowledge, and could weigh information dependent of the stage of treatment decision.
Source: European Journal of Cancer - October 7, 2013 Category: Cancer & Oncology Authors: Christiane Reinert, Lukas Kremmler, Susen Burock, Ulrich Bogdahn, Wolfgang Wick, Christoph H. Gleiter, Michael Koller, Peter Hau Tags: Neuro-oncology Source Type: research

The management of pineal tumors as a model for a multidisciplinary approach in neuro-oncology.
Abstract The management of pineal tumors is a model for multidisciplinarity. Apart from an emergency situation that requires immediate shunting of cerebrospinal fluid (CSF), the initial discussion should involve at least a radiologist, a surgeon, a neurologist and an oncologist. The initial decision is whether obtaining a histological proof is obligatory. It depends on age and ethnicity, site (mono- or bifocality), presence of markers in serum as well as CSF, and/or of malignant cells in the CSF. In cases of marker elevation indicating a germ cell tumor, front line chemotherapy can avoid dangerous immediate surger...
Source: Neuro-Chirurgie - May 23, 2014 Category: Neurosurgery Authors: Frappaz D, Conter CF, Szathmari A, Valsijevic A, Mottolese C Tags: Neurochirurgie Source Type: research