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Total 86952 results found since Jan 2013.

Conjunctival Biopsy to Diagnose Neurosarcoidosis in Patients with Inflammatory Nervous System Disease of Unknown Etiology (P1.339)
CONCLUSIONS: This study demonstrates that conjunctival biopsy has low diagnostic yield to discover neurosarcoidosis in patients with presumed inflammatory nervous system disease and suggests that alternative diagnostic means should be pursued.Disclosure: Dr. Pichler has nothing to disclose. Dr. Flanagan has nothing to disclose. Dr. Aksamit has nothing to disclose. Dr. Leavitt has nothing to disclose. Dr. Salomao has nothing to disclose. Caridian BCT
Source: Neurology - April 8, 2015 Category: Neurology Authors: Pichler, M., Flanagan, E., Aksamit, A., Leavitt, J., Salomao, D., Keegan, M. Tags: Neuro-ophthalmology/Neuro-otology I Source Type: research

Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment
Although often regarded as a protean illness with myriad clinical and imaging manifestations, neurosarcoidosis typically presents as recognizable syndromes that can be approached in a rational, systematic fashion. Understanding of neurosarcoidosis has progressed significantly in recent years, including updated diagnostic criteria and advances in treatment. The diagnosis of neurosarcoidosis is established by the clinical syndrome, imaging and histopathological findings, and exclusion of other causes. Mounting evidence supports the use of tumor necrosis factor inhibitors as an important addition to the therapeutic armamentar...
Source: Neurology Neuroimmunology and Neuroinflammation - October 4, 2021 Category: Neurology Authors: Bradshaw, M. J., Pawate, S., Koth, L. L., Cho, T. A., Gelfand, J. M. Tags: Optic neuritis; see Neuro-ophthalmology/Optic Nerve, Transverse myelitis Views [amp ] Reviews Source Type: research

Telemedicine for neuro-ophthalmology: challenges and opportunities
Purpose of review Telemedicine for neuro-ophthalmology (tele-neuro-ophthalmology) has the potential to increase access to neuro-ophthalmic care by improving efficiency and decreasing the need for long-distance travel for patients. Requirements for decreased person-to-person contacts during the COVID-19 pandemic accelerated adoption of tele-neuro-ophthalmology. This review highlights the challenges and opportunities with tele-neuro-ophthalmology. Recent findings Tele-neuro-ophthalmology programs can be used for triage, diagnostic consultation, and long-term treatment monitoring. Formats include telephone appointm...
Source: Current Opinion in Neurology - January 21, 2021 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Heather E. Moss Source Type: research

Imaging and Cerebrospinal Fluid Biomarkers in the Search for Alzheimer's Disease Mechanisms.
Conclusion: Our results indicate a heterogeneous biomarker expression, suggesting diversity of AD pathways in at-risk presymptomatic subjects. © 2013 S. Karger AG, Basel. PMID: 24107601 [PubMed - as supplied by publisher]
Source: Neuro-Degenerative Diseases - October 2, 2013 Category: Neurology Authors: Osorio RS, Pirraglia E, Gumb T, Mantua J, Ayappa I, Williams S, Mosconi L, Glodzik L, de Leon MJ Tags: Neurodegener Dis Source Type: research

Neuro-oncology Telemedicine Follow-up Visits (P7.274)
CONCLUSIONS: These data suggest that neuro-oncology can be practiced safely and effectively using a telemedicine system, with high levels of patient satisfaction.Disclosure: Dr. Green has nothing to disclose. Dr. Woyshner has nothing to disclose. Dr. Hauser Dehaven has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Green, R., Woyshner, E., Hauser Dehaven, A. Tags: Neuro-oncology: Primary CNS Tumors: Gliomas Source Type: research

The Neurologic Assessment in Neuro-Oncology (NANO) Scale: A Tool to Assess Neurologic Function for Integration in the Radiologic Assessment in Neuro-Oncology (RANO) Criteria (S22.005)
CONCLUSIONS: The NANO criteria provide a more detailed and objective measure of neurologic function than currently exists for brain tumor patients. These criteria enable a consistent evaluation of neurologic function that can be assessed across clinical trials and therapeutic interventions. Implementation and validation of these criteria are planned and will likely be regularly refined for further optimization.Disclosure: Dr. Nayak has nothing to disclose. Dr. DeAngelis has received personal compensation for activities with the NFL Players Association as a consultant. Dr. Wen has received personal compensation for activiti...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Nayak, L., DeAngelis, L., Wen, P., Brandes, A., Soffietti, R., Lin, N., Peereboom, D., Chamberlain, M., Macdonald, D., Galanis, E., Perry, J., Jaeckle, K., Mehta, M., Stupp, R., Van Den Bent, M., Reardon, D. Tags: Neuro-oncology Source Type: research

Yield of the Clinical Neuro-Ophthalmologic Examination in Patients with Concussion (P4.274)
Conclusions: Results of this neuro-ophthalmic concussion study are concordant with existing literature showing a fairly high incidence of convergence insufficiency. Interestingly, other eye movement abnormalities were rare and saccadic deficits were not detected, emphasizing the need for additional performance measures or eye movement recordings to capture concussion-related efferent visual deficits.Disclosure: Dr. Dempsey has nothing to disclose. Dr. Birkemeier has nothing to disclose. Dr. Rizzo has nothing to disclose. Dr. Hasanaj has nothing to disclose. Dr. Balcer has received personal compensation for activities with ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Dempsey, K., Birkemeier, J., Rizzo, J.-R., Hasanaj, L., Balcer, L., Galetta, S., Rucker, J. Tags: Neuro-ophthalmology/Neuro-otology Source Type: research

Diagnostic error and neuro-ophthalmology
Purpose of review This review summarizes the recent literature on diagnostic error relevant to the practice of neuro-ophthalmology, and evaluates the potential for increased access to neuro-ophthalmology to decrease rates of diagnostic error, thereby reducing medical harm and spending on unnecessary tests and treatments. Recent findings Despite medical advances, current research continues to show alarmingly high rates of diagnostic error. Research into diagnostic error shows that many of these errors can be traced to cognitive errors. Recent studies on diagnostic problems relevant to neuro-ophthalmology, including stu...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Valérie Biousse Source Type: research

Neuro-protection and neuro-regeneration of the optic nerve: recent advances and future directions
Purpose of review Optic neuropathies refer to a collection of diseases in which retinal ganglion cells (RGCs), the specialized neuron of the retina whose axons make up the optic nerve, are selectively damaged. Blindness secondary to optic neuropathies is irreversible as RGCs do not have the capacity for self-renewal and have a limited capacity for self-repair. Numerous strategies are being developed to either prevent further RGC degeneration or replace the cells that have degenerated. In this review, we aim to discuss known limitations to regeneration in central nervous system (CNS), followed by a discussion of previous,...
Source: Current Opinion in Neurology - January 17, 2020 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Heather E. Moss Source Type: research

Hemodynamic neuro-ophthalmic complications from hemodialysis (P5.191)
Conclusions:Hemodialysis patients have complex hemodynamic issues rarely seen in other populations. Right sided AV fistulas may raise the central venous pressure and result in elevated intracranial pressure particularly with coexistent venous pathology. In addition, dialysis patients often have widespread vascular disease and auto regulatory dysfunction being more sensitive to hypotensive complications from ultrafiltration. Clinicians should be aware of the neuro-ophthalmic complications specific to this population in order to diagnose and manage such complications effectively.Disclosure: Dr. Rasool has nothing to disclose...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rasool, N., Meyers, P., Cestari, D., Rostanski, S., Nowygrod, R., Moazami, G., Odel, J., Patel, A., Gallagher, B. Tags: Neuro-ophthalmology/Neuro-otology I Source Type: research

Initial Validation of a Novel Neuro-Ophthalmologic Set-Shifting Saccade Task (P3.336)
Conclusions: The high degree of correlation between these two tasks begins to indicate that the CST is a valid measure of neuro-ophthalmologic assessment. Future studies will need to determine the sensitivity of this set-shifting saccade task to assess developmental abnormalities and concussion.Disclosure: Dr. Simon has received personal compensation for activities with Cerora, Inc. as an owner, director, officer, and employee. Dr. Martino has nothing to disclose. Dr. Devilbiss has received personal compensation for activities with NexStepBiomarkers LLC and Cerora, Inc. as an owner.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Simon, A., Martino, S., Devilbiss, D. Tags: Neuro Trauma and Sports Neurology Source Type: research

Emerging Subspecialties in Neurology: Neuro-ophthalmology
Neuro-ophthalmology bridges the gap between 2 distinct yet related specialties: neurology and ophthalmology. Specifically, it focuses on the aspects of the nervous system involved with vision, including the afferent and efferent visual systems.1 Using the eye as a lens to view neurologic and systemic disease, neuro-ophthalmologists can identify preliminary signs and symptoms that, if untreated, can result in a myriad of complications due to a wide range of diseases, including optic neuritis, nystagmus, papilledema, diplopia, Horner syndrome, intracranial pressure problems, multiple sclerosis, and many more.2 As a result, n...
Source: Neurology - May 22, 2016 Category: Neurology Authors: Desai, A., Stelzer, J., Desai, S., Berman, S. Tags: All Neuro-ophthalmology, Other Education RESIDENT AND FELLOW SECTION Source Type: research

Inpatient Use of Bevacizumab in Neuro-Oncology Patients - Challenges and Practice (P1.171)
Conclusions:Amongst a diverse sample of neuro-oncology practitioners, there is general consensus that bevacizumab is an important and effective drug for CNS tumors and there are frequently cases where inpatient use is warranted. However, a sizable proportion have encountered difficulties in obtaining approval for inpatient use. These data motivate the creation of standardized policies for inpatient bevacizumab use that balances its important role in improving quality-of-life with financial considerations.Disclosure: Dr. Sharma has nothing to disclose. Dr. Low has nothing to disclose. Dr. Wax has nothing to disclose. Dr. Mr...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Sharma, A., Low, J., Wax, J., Mrugala, M. Tags: Neuro-oncology: Gliomas I Source Type: research

Arquivos de Neuro-Psiquiatria: 75 years
ABSTRACT This year marks the 75th year of publication of Arquivos de Neuro-Psiquiatria (ANP), the official journal of the Brazilian Academy of Neurology and one of the most important neuroscience journals in Latin America. ANP was initially edited by Oswaldo Lange, its founder, and subsequently by Antonio Spina-Fran ça Netto and, in recent years, by José Antonio Livramento and Luís dos Ramos Machado.RESUMO Arquivos de Neuro-Psiquiatria (ANP), o peri ódico oficial da Academia Brasileira de Neurologia, completou 75 anos de atividades, reconhecido como um dos jornais de neurociências mais importante da América Latina. N...
Source: Arquivos de Neuro-Psiquiatria - January 22, 2018 Category: Neurology Source Type: research

Spaceflight associated neuro-ocular syndrome
Purpose of review Several decades of long duration space flight missions by the National Aeronautics and Space Administration has revealed an interesting and unique constellation of neuro-ophthalmic findings now called spaceflight associated neuro-ocular syndrome (SANS). The unique space environment of microgravity produces novel physiological changes and derangements that present a challenge to astronauts in current and future long duration space missions. Although the precise mechanism of SANS is not fully understood, in this review, we examine recent developments that may to help explain possible causes and potential ...
Source: Current Opinion in Neurology - January 17, 2020 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Heather E. Moss Source Type: research