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Total 71423 results found since Jan 2013.

Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
Abstract There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation). Compelling clinical data also support the safety of carmustine wafer implantation (grade A recommendation) in these patients and suggest that observed adverse events ca...
Source: Neuro-Chirurgie - November 6, 2017 Category: Neurosurgery Authors: Roux A, Caire F, Guyotat J, Menei P, Metellus P, Pallud J, Neuro-Oncology Club of the French Neurosurgical Society Tags: Neurochirurgie Source Type: research

Ni-47 * gliomatosis meningi and gliomatosis cerebri: kissing cousins? case report and review of the literature
We report the case of a 63 year-old man who first presented with a grand mal seizure followed by progressive neurological decline, hydrocephalus, and spinal radiculopathy. He had an initial tentative diagnosis of neurosarcoidoisis radiographically. He went on to have progressive leptomeningeal enhancement on MRI involving the brain and the spinal cord with a negative initial temporal lobe biopsy followed by a subsequent biopsy of the leptomeninges, which revealed Leptomeningeal Gliomatosis. He continued to decline clinically and died 9 months after symptom onset despite treatment with craniospinal radiation therapy and che...
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Khouri, J., Taylor, L. Tags: NEURO-IMAGING (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research

Qlif-24. assessing the beneficial impacts of the neuro-oncology hospitalist practice model: pilot run at uc irvine
CONCLUSION:This new inpatient neuro-oncology hospitalist practice model has shown benefits for our neuro-onc patients and the hospital: it shortens the length of stay, increases DRG score, satisfaction of the patient, family, and the variety of the primary and other consulting services. Benefits of this model over a longer period shall be further investigated.
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Kong, X.-T., Fu, D. Tags: QUALITY OF LIFE Source Type: research

Neuro-oncology Telemedicine Follow-up Visits (P7.274)
CONCLUSIONS: These data suggest that neuro-oncology can be practiced safely and effectively using a telemedicine system, with high levels of patient satisfaction.Disclosure: Dr. Green has nothing to disclose. Dr. Woyshner has nothing to disclose. Dr. Hauser Dehaven has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Green, R., Woyshner, E., Hauser Dehaven, A. Tags: Neuro-oncology: Primary CNS Tumors: Gliomas Source Type: research

Ql-10 * neuro-oncology telemedicine follow-up visits
We report our 18 month experience with the use of a videoconferencing system to perform neuro-oncology follow-up visits. The Neuro-oncology Program at the Kaiser Permanente-Los Angeles Medical center serves the majority of Kaiser HMO patients in the Southern California region. We installed a videoconferencing system (Cisco TelePresence EX90, Cisco Systems, San Jose, CA) in our office in Los Angeles and in a medical office building in Anaheim, CA at a distance of 35 miles. Established neuro-oncology patients from Orange County chose between in-person and remote visits. Patients were seated in an examination room and the neu...
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Green, R., Woyshner, E. Tags: QUALITY OF LIFE Source Type: research

Development of the Pediatric Neuro-Oncology Rating of Treatment Intensity (PNORTI)
AbstractMeasures of treatment intensity for childhood cancer are needed in research in order to control for variability in treatments. Existing measures of treatment intensity for childhood cancers do not reflect the complexities of treatment protocols for central nervous system (CNS) tumors. This paper describes the development of the Pediatric Neuro-Oncology Rating of Treatment Intensity (PNORTI). PNORTI development occurred in three phases. Phase 1: five experts in pediatric neuro-oncology created a 5-point scale of treatment intensity and 42 pediatric neuro-oncology providers completed a three-part online questionnaire...
Source: Journal of Neuro-Oncology - September 8, 2017 Category: Cancer & Oncology Source Type: research

P21.04 Clinical pathway in glioma management; from NOSC (Neuro-Oncology Scientific Club) meetings to bedside practice
Characterizing a working-team concept in the practice of neuro-oncology requires continued interdisciplinary efforts. The Neuro-Oncology Scientific Club (NOSC) initiative is an interdisciplinary clinical forum which has been operational in Iran since 2011 attempting towards a connect-approach in the management of CNS malignancies. NOSC comprises nation-wide group of experts and pursues its mission through interval strategic meetings, tumor-boards, case-discussions as well as publishing neuro-oncology updates and newsletters. The most recent NOSC clinical forum in Mashhad (February 2016), put together insights from internat...
Source: Neuro-Oncology - September 20, 2016 Category: Cancer & Oncology Authors: Anvari, K., Fazl Ersi, M., Etemad-Rezaie, H., Nekooie, S., Arbabi, F., Ganjeifar, B., Bidouei, F., Nikkhah, K., Afarid, M., Torabi-Nami, M. Tags: P21 Miscellaneous Source Type: research

Factors associated with supportive care needs in glioma patients in the neuro-oncological outpatient setting
AbstractObjective of this study aimed at assessing glioma patients ’ supportive care needs in a neurosurgical outpatient setting and identifying factors that are associated with needs for support. In three neuro-oncological outpatient departments, glioma patients were assessed for their psychosocial needs using the Supportive Care Needs Survey short-form (SCNS-SF 34-G). Associations between clinical, sociodemographic, treatment related factors as well as distress (measured with the distress thermometer) and supportive care needs were explored using multivariable general linear models. One-hundred and seventy three of 244...
Source: Journal of Neuro-Oncology - May 19, 2017 Category: Cancer & Oncology Source Type: research

Sm-08 * neuro-oncological patients admitted in intensive-care unit (icu): patient's characteristics, predictive factors of death in icu and functional outcome
CONCLUSION: In patient with malignant brain tumor,admitted in ICU, predictive factors of death appear to be similar to those described in non-oncological patients. ICU hospitalization is generally not associated with a subsequent decrease of functional status.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Tabouret, E., Boucard, C., Barrie, M., Autran, D., Bruder, N., Chinot, O. Tags: SYMPTOM MANAGEMENT Source Type: research

Randomized controlled trials and neuro-oncology: should alternative designs be considered?
Abstract Deficiencies in design and reporting of randomized controlled trials (RCTs) hinders interpretability and critical appraisal. The reporting quality of recent RCTs in neuro-oncology was analyzed to assess adequacy of design and reporting. The MEDLINE and EMBASE databases were searched to identify non-surgical RCTs (years 2005–2014, inclusive). The CONSORT and Jadad scales were used to assess the quality of design/reporting. Studies published in 2005–2010 were compared as a cohort against studies published in 2011–2014, in terms of general characteristics and reporting quality. A PRECIS-based scale was...
Source: Journal of Neuro-Oncology - August 21, 2015 Category: Cancer & Oncology Source Type: research

The management of pineal tumors as a model for a multidisciplinary approach in neuro-oncology.
Abstract The management of pineal tumors is a model for multidisciplinarity. Apart from an emergency situation that requires immediate shunting of cerebrospinal fluid (CSF), the initial discussion should involve at least a radiologist, a surgeon, a neurologist and an oncologist. The initial decision is whether obtaining a histological proof is obligatory. It depends on age and ethnicity, site (mono- or bifocality), presence of markers in serum as well as CSF, and/or of malignant cells in the CSF. In cases of marker elevation indicating a germ cell tumor, front line chemotherapy can avoid dangerous immediate surger...
Source: Neuro-Chirurgie - May 23, 2014 Category: Neurosurgery Authors: Frappaz D, Conter CF, Szathmari A, Valsijevic A, Mottolese C Tags: Neurochirurgie Source Type: research

Ncog-17. evaluation of neurocognitive function in patients with cerebellar medulloblastoma
DISCUSSION:While lesions in the cerebellum are not classically associated with neurocognitive dysfunction, this retrospective analysis demonstrates significant neurocognitive dysfunction in a cohort of patients with predominantly adult CM. Increased study is warranted to more fully characterize the clinical impact of CM and its treatments in our patients.
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Harrison, R. A., Johnson, J. M., Sullaway, C. M., Wefel, J. S. Tags: NEURO-COGNITIVE OUTCOMES Source Type: research

Prevention and management of postoperative seizures in neuro-oncology.
CONCLUSION: These guidelines are helpful for a rational therapy in tumoral epilepsy. PMID: 28599984 [PubMed - as supplied by publisher]
Source: Neuro-Chirurgie - June 6, 2017 Category: Neurosurgery Authors: Chassoux F, Landre E Tags: Neurochirurgie Source Type: research

Quality indicators in neuro-oncology: Review of the literature and development of a new quality indicator set for glioma care through a two-round Delphi survey
ConclusionThis study defined a set of 47 QIs for assessing quality of care in adult glioma patients, distributed amongst 7 crucial phases in the patient ’s care trajectory. These QIs are readily applicable for use in diverse health care systems, depending on the availability of population-based health care data enabling (inter)national benchmarking.
Source: Journal of Neuro-Oncology - March 11, 2022 Category: Cancer & Oncology Source Type: research

Clinicopathologic analysis of pineal parenchymal tumors of intermediate differentiation: a multi-institutional cohort study by the Kyushu Neuro-Oncology Study Group
ConclusionsFemale sex and GTR were independent prognostic factors in our patients with PPTID. Leptomeningeal recurrence was observed to be particularly characteristic of this tumor. The rate ofKBTBD4 mutation observed in our cohort was acceptable and this could prove the accuracy of our PPTID cohort.
Source: Journal of Neuro-Oncology - April 13, 2023 Category: Cancer & Oncology Source Type: research