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CROI 2023: Neuropsychiatric Complications in People With HIV
Top Antivir Med. 2023 Jun 30;31(4):543-555.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured new and impactful findings about neuropsychiatric complications in people with HIV and other infections. Reports included new evidence of (a) the importance of myeloid cells in the pathogenesis of HIV disease in the central nervous system, including as an HIV reservoir; (b) eukaryotic and prokaryotic viruses in cerebrospinal fluid during suppressive antiretroviral therapy; (c) the influence of sex on pathogenesis, including in novel neuropsychiatric biotypes identified by machine learning and ...
Source: Topics in antiviral medicine - September 13, 2023 Category: Infectious Diseases Authors: Albert M Anderson Beau M Ances Scott L Letendre Source Type: research
Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer
Urologie. 2023 Sep 13. doi: 10.1007/s00120-023-02189-z. Online ahead of print.ABSTRACTProstate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens up new diagnostic opportunities. PSMA-PET/CT (PET: positron-emission tomography) is already well established in high-risk PCa for primary staging and tumor localization when biochemical recurrence occurs. Further potential indications for PSMA-...
Source: Nuklearmedizin - September 13, 2023 Category: Radiology Authors: Anna-Sophie Strau ß Christian Bolenz Ambros J Beer Friedemann Zengerling Meinrad Beer Jonathan Miksch Source Type: research
Cerebral arterial flow dynamics during systole and diastole phases in young and older healthy adults
ConclusionOur study provides a novel contribution on the influence of the cardiac cycle phases on cerebral arterial flow. The main contribution in this study concerns the identification of age-related alterations in cerebral blood flow, which occur mainly during the diastolic phase. Specifically, we observed that mean flow significantly decreases with age during diastole, whereas mean flow during systole is consistent.
Source: Fluids and Barriers of the CNS - September 13, 2023 Category: Neuroscience Source Type: research
Femoroacetabular impingement in adolescents
Radiologie (Heidelb). 2023 Sep 12. doi: 10.1007/s00117-023-01197-6. Online ahead of print.ABSTRACTFemoroacetabular impingement syndrome (FAIS) is caused by a repetitive mechanical conflict between the acetabulum and the proximal femur, occurring in flexion and internal rotation. In cam impingement, bony prominences of the femoral head-neck junction induce chondrolabral damage. The acetabular type of FAIS, termed pincer FAIS, may be either due to focal or global retroversion and/or acetabular overcoverage. Combinations of cam and pincer morphology are common. Pathological femoral torsion may aggravate or decrease the mechan...
Source: Nuklearmedizin - September 12, 2023 Category: Radiology Authors: Iris-M Noebauer-Huhmann Felix R M Koenig Catharina Chiari Florian Schmaranzer Source Type: research
Associations Between Cognitive Impairment and Neuroimaging in Patients with Multiple Sclerosis
CONCLUSIONS: These findings demonstrate an independent association between thalamic volumes and processing speed and memory performance, after accounting for demographic, clinical, and other MRI variables, among pwMS.PMID:37699528 | DOI:10.1093/arclin/acad070
Source: Archives of Clinical Neuropsychology - September 12, 2023 Category: Psychiatry & Psychology Authors: Olivia Wilcox Moein Amin Laura Hancock Kunio Nakamura John Lace Daniel Ontaneda Rachel Galioto Source Type: research
The Piano Man: A Case Report of Anterior Thalamic Infarct with Dementia and Preserved Music Ability
CONCLUSIONS: The case has implications for understanding the complex integrative functions of the thalamus, including how profound impairment can simultaneously present with cognitive strengths that may not be captured by performance on neuropsychological testing. This case also suggests that magnetic resonance imaging may be indicated in cases presenting with vascular risk factors and sudden onset cognitive impairment, given that computed tomography may not be sensitive to small subcortical infarcts.PMID:37699427 | DOI:10.1093/arclin/acad069
Source: Archives of Clinical Neuropsychology - September 12, 2023 Category: Psychiatry & Psychology Authors: Ashleigh F Parker Theone S E Paterson Tamara Goranson Jodie R Gawryluk Source Type: research
Femoroacetabular impingement in adolescents
Radiologie (Heidelb). 2023 Sep 12. doi: 10.1007/s00117-023-01197-6. Online ahead of print.ABSTRACTFemoroacetabular impingement syndrome (FAIS) is caused by a repetitive mechanical conflict between the acetabulum and the proximal femur, occurring in flexion and internal rotation. In cam impingement, bony prominences of the femoral head-neck junction induce chondrolabral damage. The acetabular type of FAIS, termed pincer FAIS, may be either due to focal or global retroversion and/or acetabular overcoverage. Combinations of cam and pincer morphology are common. Pathological femoral torsion may aggravate or decrease the mechan...
Source: Nuklearmedizin - September 12, 2023 Category: Radiology Authors: Iris-M Noebauer-Huhmann Felix R M Koenig Catharina Chiari Florian Schmaranzer Source Type: research
GRECCAR 14 - a multicentric, randomized, phase II-III study evaluating the tailored management of locally advanced rectal carcinoma after a favourable response to induction chemotherapy: study protocol
CONCLUSION: If GRECCAR 14 demonstrates the ability to tailor TNT for LARC, this could lead to changes in clinical practice.PMID:37697712 | DOI:10.1111/codi.16740
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Philippe Rouanet Florence Castan Thibault Mazard Claire Lemanski Stephanie Nougaret Emmanuel Deshayes Patrick Chalbos Sophie Gourgou Christophe Taoum GRECCAR, PRODIGE study group Source Type: research
Associations Between Cognitive Impairment and Neuroimaging in Patients with Multiple Sclerosis
CONCLUSIONS: These findings demonstrate an independent association between thalamic volumes and processing speed and memory performance, after accounting for demographic, clinical, and other MRI variables, among pwMS.PMID:37699528 | DOI:10.1093/arclin/acad070
Source: Archives of Clinical Neuropsychology - September 12, 2023 Category: Psychiatry & Psychology Authors: Olivia Wilcox Moein Amin Laura Hancock Kunio Nakamura John Lace Daniel Ontaneda Rachel Galioto Source Type: research
The Piano Man: A Case Report of Anterior Thalamic Infarct with Dementia and Preserved Music Ability
CONCLUSIONS: The case has implications for understanding the complex integrative functions of the thalamus, including how profound impairment can simultaneously present with cognitive strengths that may not be captured by performance on neuropsychological testing. This case also suggests that magnetic resonance imaging may be indicated in cases presenting with vascular risk factors and sudden onset cognitive impairment, given that computed tomography may not be sensitive to small subcortical infarcts.PMID:37699427 | DOI:10.1093/arclin/acad069
Source: Archives of Clinical Neuropsychology - September 12, 2023 Category: Psychiatry & Psychology Authors: Ashleigh F Parker Theone S E Paterson Tamara Goranson Jodie R Gawryluk Source Type: research
Seed correlation analysis based on brain region activation for ADHD diagnosis in a large-scale resting state data set
ConclusionThis preliminary study examines the feasibility of diagnosing ADHD by analyzing the resting-state fMRI data from the ADHD-200 NYU dataset. The data-driven model provides a precise way to find reliable seeds. Data-driven models offer precise methods for finding reliable seeds and are feasible across different datasets. Moreover, this phenomenon may reveal that using a data-driven approach to build a model specific to a single data set may be better than combining several data and creating a general model.
Source: Frontiers in Human Neuroscience - September 12, 2023 Category: Neuroscience Source Type: research
Research on application of radiomics in glioma: a bibliometric and visual analysis
ConclusionIn the past decade, radiomics has received much attention in the medical field and has been widely used in clinical research applications. Cooperation and communication between countries/regions need to be enhanced in future research to promote the development of radiomics in the field of medicine. In addition, the application of radiomics has improved the accuracy of pre-treatment diagnosis, efficacy prediction and prognosis assessment of glioma and helped to promote the development into precision medicine, the future still faces many challenges.
Source: Frontiers in Oncology - September 12, 2023 Category: Cancer & Oncology Source Type: research
Functional Alterations of the Basal Ganglia Are Associated with Voluntary Activation of the Core Stabilizing Muscles in Patients with Chronic Low Back Pain: A Cross-Sectional Study
CONCLUSIONS: Grey matter alterations may be confined to regions responsible for perception, motor control, and emotion regulation in patients with CLBP. The interrupted EC from the basal ganglia to the default mode network might be involved in the impairment of voluntary activation of the core stabilizing muscles.PMID:37693681 | PMC:PMC10484657 | DOI:10.1155/2023/2028379
Source: Pain Research and Management - September 11, 2023 Category: Anesthesiology Authors: Chanjuan Zhang Xi Chen Yi Yin Dongfeng Xie Jing Luo Yinan Ai Wenfeng Zhan Hongjun Kan Shuxian Zhang Guihua Jiang Xiquan Hu Source Type: research
