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Specialty: Neurology
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Total 86952 results found since Jan 2013.
Metacognition and sense of agency
Cognition. 2023 Sep 14;241:105622. doi: 10.1016/j.cognition.2023.105622. Online ahead of print.ABSTRACTIntelligent agents need to understand how they can change the world, and how they cannot change it, in order to make rational decisions for their forthcoming actions, and to adapt to their current environment. Previous research on the sense of agency, based largely on subjective ratings, failed to dissociate the sensitivity of sense of agency (i.e., the extent to which individual sense of agency tracks actual instrumental control over external events) from judgment criteria (i.e., the extent to which individuals self-attr...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Wen Wen Lucie Charles Patrick Haggard Source Type: research
Divergences in color perception between deep neural networks and humans
Cognition. 2023 Sep 14;241:105621. doi: 10.1016/j.cognition.2023.105621. Online ahead of print.ABSTRACTDeep neural networks (DNNs) are increasingly proposed as models of human vision, bolstered by their impressive performance on image classification and object recognition tasks. Yet, the extent to which DNNs capture fundamental aspects of human vision such as color perception remains unclear. Here, we develop novel experiments for evaluating the perceptual coherence of color embeddings in DNNs, and we assess how well these algorithms predict human color similarity judgments collected via an online survey. We find that stat...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Ethan O Nadler Elise Darragh-Ford Bhargav Srinivasa Desikan Christian Conaway Mark Chu Tasker Hull Douglas Guilbeault Source Type: research
Multiple predictions during language comprehension: Friends, foes, or indifferent companions?
Cognition. 2023 Sep 14;241:105602. doi: 10.1016/j.cognition.2023.105602. Online ahead of print.ABSTRACTTo comprehend language, we continually use prior context to pre-activate expected upcoming information, resulting in facilitated processing of incoming words that confirm these predictions. But what are the consequences of disconfirming prior predictions? To address this question, most previous studies have examined unpredictable words appearing in contexts that constrain strongly for a single continuation. However, during natural language processing, it is far more common to encounter contexts that constrain for multiple...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Trevor Brothers Emily Morgan Anthony Yacovone Gina Kuperberg Source Type: research
Cognitive function and the longitudinal hippocampal axis in mesial temporal sclerosis
CONCLUSIONS: Ipsilateral hippocampal head and tail seem more vulnerable to injury than the body in both the left and right mTLE. Our study suggests there may be functional differences along the hippocampal longitudinal axis, particularly for the left hippocampal tail with verbal memory. Our findings are consistent with material-specific right-left differences in memory processing.PMID:37716331 | DOI:10.1016/j.yebeh.2023.109413
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: L Reppert L N Sepeta D Panjeti-Moore E Akinsoji C Sherer A Hamidullah-Thiam W H Theodore Source Type: research
Referral odyssey plot to visualize causes of surgical delay in mesial temporal lobe epilepsy with hippocampal sclerosis
Epilepsy Behav. 2023 Sep 14;147:109434. doi: 10.1016/j.yebeh.2023.109434. Online ahead of print.ABSTRACTThe "odyssey plot" was used to visualize referral delays in epilepsy surgery. Participants were 36 patients (19 males; 13-67 years, median 27 years) with mesial temporal lobe epilepsy with hippocampal sclerosis (HS) who underwent resection surgery. The "referral odyssey plot" included five clinical episodes: seizure onset (T1), first visits to a non-epileptologist (T2) and to an epileptologist (T3), first admission to our epilepsy monitoring unit (EMU) (T4), and resection surgery (T5). For each patient, we identified the...
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Kazutoshi Konomatsu Yosuke Kakisaka Makoto Ishida Temma Soga Kazushi Ukishiro Shin-Ichiro Osawa Kazutaka Jin Masashi Aoki Nobukazu Nakasato Source Type: research
Risk of suicide and religious or spiritual beliefs in Brazilian adult patients with epilepsy
DISCUSSION: A high number of patients with epilepsy exhibited suicide risk, with epilepsy-related variables, the presence of anxiety, and perceived lower belongingness and social support from religiosity or spirituality anxiety being associated with a higher risk. The social support provided by religiosity/spirituality may be a non-clinical factor associated with suicidal behavior. Suicide in epilepsy is associated with a complex interaction of multidimensional factors.PMID:37716329 | DOI:10.1016/j.yebeh.2023.109414
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Yasmin Meneguci Petrarca Gl ória M A S Tedrus Source Type: research
Hypothalamic hamartoma surgery in a setting with limited resources
CONCLUSION: Hypothalamic hamartoma surgery is feasible even in centers with limited resources if a close collaboration exists between the epileptology and neurosurgery teams. Careful planning based on the expertise of the team members and the available resources is required to foster success.PMID:37716328 | DOI:10.1016/j.yebeh.2023.109439
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ali A Asadi-Pooya Mohamad S Masoudi Bita Hashemi Seyedarad Mosalamiaghili Masoume Nazeri Khatereh Fazelian Source Type: research
Reliability and validation of the Chinese version of the epilepsy surgery satisfaction questionnaire
CONCLUSIONS: The C-ESSQ-19 has proven to be a reliable and valid self-rated questionnaire for assessing the satisfaction of Chinese mainland epilepsy patients with surgery.PMID:37716327 | DOI:10.1016/j.yebeh.2023.109438
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Qun Yu Yu-Qi Ying Si-Xuan Jiang Zheng-Yan-Ran Xu Mei-Juan Lan Yi Guo Source Type: research
Co-production of online educational resources for adolescent and young adult females with epilepsy
CONCLUSION: Our team utilized co-production with a diverse group of partners to create educational materials that met the interests of adolescent and young adult females with epilepsy. This is a structured and reproducible methodology that could inform future educational intervention development in epilepsy.PMID:37716326 | DOI:10.1016/j.yebeh.2023.109420
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Medha Parulekar Traci M Kazmerski Danielle Gordon Tahniat Syed Janet F R Waters Anne C Van Cott Laura Kirkpatrick Source Type: research
Seizure-related stress and arousal responses mediate a relationship between anxiety trait and state in epilepsy
CONCLUSIONS: These findings elucidate the epilepsy-specific stress and arousal characteristics and their roles in mediating traits and state anxiety. These results may reflect the long-term clinical course and unique emotion recognition tendencies in epilepsy.PMID:37716325 | DOI:10.1016/j.yebeh.2023.109442
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Hironobu Nakamura Genichi Sugihara Keiko Hara Motoki Inaji Masahiro Noha Ichiro Takumi Masako Watanabe Hidehiko Takahashi Taketoshi Maehara Hitoshi Yamamoto Shunsuke Takagi Source Type: research
Prevalence and predictors of vitamin D deficiency among adults with epilepsy: A cross-sectional study
CONCLUSION: Vitamin D deficiency among PWE is prevalent in our local population, suggesting that regular screening should be considered for those at risk. Early identification would allow intervention to reduce the risk of future complications.PMID:37716324 | DOI:10.1016/j.yebeh.2023.109432
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ching Soong Khoo Mohd Fadzli Shukor Juen Kiem Tan Michelle Maryanne Tan Li Ling Yong Siti Zaleha Sahibulddin Siti Hajar Mat Desa Norasyikin A Wahab Rozita Hod Hui Jan Tan Source Type: research
Microvascular blood-brain barrier alterations in isolated brain capillaries of mice over-expressing alpha-synuclein (Thy1-aSyn line 61)
Neurobiol Dis. 2023 Sep 14:106298. doi: 10.1016/j.nbd.2023.106298. Online ahead of print.ABSTRACTDysfunction of the blood-brain barrier (BBB) is suggested to play a critical role in the pathological mechanisms of Parkinson's disease (PD). PD-related pathology such as alpha-synuclein accumulation and inflammatory processes potentially affect the integrity of the BBB early in disease progression, which in turn may alter the crosstalk of the central and peripheral immune response. Importantly, BBB dysfunction could also affect drug response in PD. Here we analyzed microvascular changes in isolated brain capillaries and brain ...
Source: Neurobiology of Disease - September 16, 2023 Category: Neurology Authors: Kristina Lau Lisa T Porschen Franziska Richter Birthe Gericke Source Type: research
Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs
In this study, HTT exon1 production was examined in the HD knock-in (KI) pig model, which more closely recapitulates neuropathology seen in HD patient brains than HD mouse models. The study revealed that aberrant spliced HTT exon1 is also present in the brains of HD pigs, but it is expressed at a much lower level than the normally spliced HTT exon products. These findings suggest that careful consideration is needed when assessing the contribution of aberrantly spliced mHTT exon1 to HD pathogenesis, and further rigorous investigation is required.PMID:37716514 | DOI:10.1016/j.nbd.2023.106291
Source: Neurobiology of Disease - September 16, 2023 Category: Neurology Authors: Huichun Tong Tianqi Yang Li Liu Caijuan Li Yize Sun Qingqing Jia Yiyang Qin Laiqiang Chen Xianxian Zhao Gongke Zhou Sen Yan Xiao-Jiang Li Shihua Li Source Type: research
Elevated CRP and TNF- α levels are associated with blunted neural oscillations serving fluid intelligence
DISCUSSION: Elevated inflammatory markers such as CRP and TNF-α were associated with aberrant neural oscillations in regions important for Gf. Linking inflammatory markers with regional neural oscillations may hold promise in identifying mechanisms of cognitive and psychiatric disorders.PMID:37716379 | DOI:10.1016/j.bbi.2023.09.012
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Sarah M Dietz Mikki Schantell Rachel K Spooner Megan E Sandal Amirsalar Mansouri Yasra Arif Hannah J Okelberry Jason A John Ryan Glesinger Pamela E May Elizabeth Heinrichs-Graham Adam J Case Matthew C Zimmerman Tony W Wilson Source Type: research
P2X < sub > 7 < /sub > R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
Brain Behav Immun. 2023 Sep 14:S0889-1591(23)00275-1. doi: 10.1016/j.bbi.2023.09.011. Online ahead of print.ABSTRACTThe purinoceptor P2X7R is a promising therapeutic target for tauopathies, including Alzheimer's disease (AD). Pharmacological inhibition or genetic knockdown of P2X7R ameliorates cognitive deficits and reduces pathological tau burden in mice that model aspects of tauopathy, including mice expressing mutant human frontotemporal dementia (FTD)-causing forms of tau. However, disagreements remain over which glial cell types express P2X7R and therefore the mechanism of action is unresolved. Here, we show that P2X7...
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Paula Beltran-Lobo Martina M Hughes Claire Troakes Cara L Croft Huzefa Rupawala Daniel Jutzi Marc-David Ruepp Maria Jimenez-Sanchez Michael S Perkinton Michael Kassiou Todd E Golde Diane P Hanger Alexei Verkhratsky Beatriz G Perez-Nievas Wendy Noble Source Type: research
