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Berberine ：A Review of Its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases
Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications. Vascular diseases affecting vasculature in the heart, cerebrovascular disease, atherosclerosis, and diabetic complications have compromise quality of life for affected individuals and increase the burden on health care services. Berberine, a naturally occurring isoquinoline alkaloid form Rhizoma coptidis, is widely used in China as a folk medicine for its anti-bacterial and anti-inflammatory properties. Promisingly, an increasing number of studies have identified sever...
Source: Frontiers in Pharmacology - November 3, 2021 Category: Drugs & Pharmacology Source Type: research

Two closely spaced missense COL3A1 variants in cis cause vascular Ehlers-Danlos syndrome in one large Chinese family
J Cell Mol Med. 2021 Nov 29. doi: 10.1111/jcmm.17063. Online ahead of print.ABSTRACTVascular Ehlers-Danlos syndrome (vEDS) is a rare and severe hereditary connective tissue disease arising from a mutation in the type III collagen alpha I chain (COL3A1) gene, with a poor prognosis due to exceptional vascular ruptures and premature death. Herein, starting from a 36-year-old Chinese male patient with a complaint of upper abdominal pain, we collected clinical data of and performed a genetic analysis of a total of 20 family members. We identified two closely spaced COL3A1 missense variants in cis, p.Leu734Phe (c.2199_2200TC>...
Source: J Cell Mol Med - November 30, 2021 Category: Molecular Biology Authors: Mei Liang Chong Chen Yan Dai Yunbing Chang Yushun Gao Source Type: research

Impact of a health campaign on Chinese public awareness of stroke: evidence from internet search data
Conclusions The WSD campaign increased internet search activity. These research techniques can be applied to evaluation of other health campaigns. Advancing understanding of public demand will enable tailoring of the campaign and strengthen health management.
Source: BMJ Open - December 14, 2021 Category: General Medicine Authors: Cao, M., Guan, T., Han, X., Shen, B., Chao, B., Liu, Y. Tags: Open access, Public health Source Type: research

Upper Facial Anastomoses Between the External and Internal Carotid Vascular Territories - A 3D Computed Tomographic Investigation
CONCLUSIONS: Adverse events following facial minimally invasive soft tissue filler injections for aesthetic purposes are not frequent but devastating if they occur. Anatomic knowledge as presented in this study can help to increase awareness of 3-dimensional vascular anastomotic pathways and to identify safer injection zones and safer fascial planes. Evidence-based injection techniques should be followed, and safety aspects should be placed over the aesthetic outcome.PMID:35305018 | DOI:10.1093/asj/sjac060
Source: Hand Surgery - March 19, 2022 Category: Surgery Authors: Zhen-Hao Li Michael Alfertshofer Wei-Jin Hong Xin-Rui Li You-Liang Zhang Nicholas Moellhoff Konstantin Frank Sheng-Kang Luo Sebastian Cotofana Source Type: research

Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial
This study indicated that vitamin C supplementation may protect vascular vessels against PM exposure among healthy young adults in China.PMID:35689890 | DOI:10.1016/j.ecoenv.2022.113735
Source: Ecotoxicology and Environmental Safety - June 11, 2022 Category: Environmental Health Authors: Jingyi Ren Jufeng Liang Jiaqi Wang Bowen Yin Fan Zhang Xiang Li Siqi Zhu Hao Tian Qiqi Cui Jianshi Song Gang Liu Wenhua Ling Yuxia Ma Source Type: research

Molecules, Vol. 27, Pages 5628: Effects of Lycium barbarum L. Polysaccharides on Vascular Retinopathy: An Insight Review
Xianrong Lai Vascular retinopathy is a pathological change in the retina caused by ocular or systemic vascular diseases that can lead to blurred vision and the risk of blindness. Lycium barbarum polysaccharides (LBPs) are extracted from the fruit of traditional Chinese medicine, L. barbarum. They have strong biological activities, including immune regulation, antioxidation, and neuroprotection, and have been shown to improve vision in numerous studies. At present, there is no systematic literature review of LBPs on vascular retinal prevention and treatment. We review the structural characterization and extraction meth...
Source: Molecules - August 31, 2022 Category: Chemistry Authors: Chunhong Yang Qi Zhao Shiling Li Lili Pu Liqiong Yu Yaqin Liu Xianrong Lai Tags: Review Source Type: research

Risk factors of dementia in patients with cerebral vascular diseases based on Taiwan National Health Insurance data
CONCLUSION: Depression, osteoporosis and the use of enalapril were associated with a higher risk of dementia, while nitroglycerin might be a protecting factor for dementia, in subjects with cerebrovascular diseases without mention of cerebral infarction.PMID:36948166 | DOI:10.1159/000530102
Source: Atherosclerosis - March 22, 2023 Category: Cardiology Authors: Bin Zhou Cheng-Li Lin Shinsuke Kojima Masanori Fukushima Chung Y Hsu Source Type: research

Long-Term Exposure to Fine Particulate Constituents and Vascular Damage in a Population with Metabolic Abnormality in China
CONCLUSION: Chronic exposure to PM2.5 and PM2.5 constituents was related to vascular damage in the abnormal metabolic population in China. The heterogeneous contribution of different PM2.5 constituents to vessel bed damage is worthy of attention when developing targeted strategies.PMID:37032101 | DOI:10.5551/jat.64062
Source: Journal of Atherosclerosis and Thrombosis - April 9, 2023 Category: Cardiology Authors: Lijin Lin Huxiang Huang Fang Lei Tao Sun Ze Chen Kun Qin Manyao Li Yingying Hu Xuewei Huang Xingyuan Zhang Peng Zhang Xiao-Jing Zhang Zhi-Gang She Jingjing Cai Shujuan Yang Peng Jia Hongliang Li Source Type: research

Dietary Evodiamine Inhibits Atherosclerosis-Associated Changes in Vascular Smooth Muscle Cells
In conclusion, our findings reveal a role for evodiamine in the regulation of vascular smooth muscle cells in atherosclerosis, highlighting a potential future role for the compound as an anti-atherosclerotic agent.PMID:37047626 | DOI:10.3390/ijms24076653
Source: Atherosclerosis - April 13, 2023 Category: Cardiology Authors: Yiwen Zha Yongqi Yang Yue Zhou Bingqian Ye Hongliang Li Jingyan Liang Source Type: research