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Total 130538 results found since Jan 2013.

Efficacy and safety of ginkgo preparation in patients with vascular dementia: A protocol for systematic review and meta-analysis
Conclusion: This systematic review will explore whether ginkgo preparation is an effective and safe intervention for vascular dementia. Ethics and dissemination: Ethical approval are not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and will be shared on social media platforms. This review will be disseminated in a peer-reviewed journal or conference presentation. PROSPERO registration number: PROSPERO CRD42020167851.
Source: Medicine - September 11, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Laparoscopic Pancreaticoduodenectomy with Superior Mesenteric Vein Resection and Artificial Vascular Graft Reconstruction for Borderline Resectable Pancreatic Cancer
ConclusionsThis study demonstrated the feasibility of total laparoscopic pancreaticoduodenectomy combined with vascular resection and artificial vascular graft reconstruction in properly selected cases of pancreatic cancer with vein involvement after neoadjuvant chemotherapy. It is worth noting that skilled laparoscopic technicians and effective teamwork are necessities for safe completion of the procedure.
Source: Journal of Gastrointestinal Surgery - October 9, 2020 Category: Surgery Source Type: research

Elevated Serum Levels of Progranulin and Soluble Vascular Cell Adhesion Molecule-1 in Patients with COVID-19
CONCLUSION: The present study demonstrates elevated serum PGRN and sVCAM-1 levels in patients with COVID-19, which may provide clues as to the mechanisms underlying the pathogenesis of COVID-19. Further studies are warranted to evaluate the potential of PGRN and sVCAM-1 as biomarkers and investigate their role in the pathogenesis of COVID-19.PMID:34584437 | PMC:PMC8464378 | DOI:10.2147/JIR.S330356
Source: Cell Research - September 29, 2021 Category: Cytology Authors: Shifei Yao Nanning Luo Jiaoyang Liu He Zha Yuanhang Ai Juan Luo Shi Shi Kaifeng Wu Source Type: research

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases
Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications. Vascular diseases affecting vasculature in the heart, cerebrovascular disease, atherosclerosis, and diabetic complications have compromised quality of life for affected individuals and increase the burden on health care services. Berberine, a naturally occurring isoquinoline alkaloid form Rhizoma coptidis, is widely used in China as a folk medicine for its antibacterial and anti-inflammatory properties. Promisingly, an increasing number of studies have identified sever...
Source: Frontiers in Pharmacology - March 14, 2022 Category: Drugs & Pharmacology Source Type: research

Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model
In this study, we investigated the therapeutic effects of ICS-Ⅱ on vascular remodeling with a rat’s balloon injury model in vivo. The label-free proteomic analysis was further implemented to identify the differentially expressed proteins (DEPs) after ICS-II intervention. Gene ontology and the pathway enrichment analysis were performed based on DEPs. Moreover, platelet-derived growth factor (PDGF-BB)-induced primary rat VSMC was implemented to verify the restoration effects of ICS-II on the VSMC contractile phenotype. Results showed that ICS-II could effectively attenuate the vascular remodeling process, promote SMA-α ...
Source: Frontiers in Pharmacology - June 13, 2022 Category: Drugs & Pharmacology Source Type: research

Icariside II Attenuates Vascular Remodeling Via Wnt7b/CCND1 Axis
In conclusion, our findings demonstrate that ICS-II possesses significant antiproliferative qualities that counteracts aberrant vascular neointimal hyperplasia. This phenomenon most likely occurs due to the suppression of the Wnt7b/CCND1 axis.
Source: Journal of Cardiovascular Pharmacology - July 1, 2022 Category: Cardiology Tags: Original Article Source Type: research

Interaction Between Vascular Endothelial Growth Factor Gene Polymorphism and Smoking on Gastric Cancer Risk in Chinese Han Population
Conclusion: We found that rs10434 -G and rs833061-T alleles, gene- environment interaction between rs10434, and current smoking were all related to increased GC risk.PMID:36091938 | PMC:PMC9454397 | DOI:10.3389/pore.2022.1610495
Source: Pathology Oncology Research - September 12, 2022 Category: Pathology Authors: Longyue Wang Shuaishuai Xiao Yiming Zheng Zefeng Gao Source Type: research

Danlou Tablet May Alleviate Vascular Injury Caused by Chronic Intermittent Hypoxia through Regulating FIH-1, HIF-1, and Angptl4
CONCLUSIONS: DLT improved vascular damage by improving the increase in blood lipids induced by CIH, potentially by upregulating FIH-1 and downregulating HIF-1 and Angptl4 in adipose tissue. Therefore, DLT may be a promising agent for the prevention and treatment of CIH-induced vascular injury.PMID:36285165 | PMC:PMC9588356 | DOI:10.1155/2022/4463108
Source: Evidence-based Complementary and Alternative Medicine - October 26, 2022 Category: Complementary Medicine Authors: Yi Rong Qian Wu Jingjing Tang Zhiguo Liu Qianyu Lv Xuejiao Ye Yu Dong Yuebo Zhang Guangxi Li Shihan Wang Source Type: research

Cost-effectiveness analysis of autogenous arteriovenous fistula, arteriovenous graft, and tunneled-cuffed catheter for hemodialysis in patients with end-stage kidney disease in Southern China
CONCLUSION: These findings illustrate the value of AVF given its relative cost-effectiveness to other hemodialysis modalities. Although AVG costs much more than TCC for slightly higher QALYs than TCC, AVG still has a greater advantage over TCC for patients with longer life expectancy due to its lower probability of death.PMID:36540049 | DOI:10.1177/11297298221143010
Source: The Journal of Vascular Access - December 21, 2022 Category: Surgery Authors: Tak-Sui Wong Qian Chen Qiongqiong Zhong Bo Hu Guanrui Feng Fengqiu Huang Jian Lu Lianghong Yin Zongchao Yu Babatunde O Akinwunmi Jian Huang Casper Jp Zhang Wai-Kit Ming Source Type: research

Use of the Vascular Overload Index to Predict Cardiovascular Disease in a Rural Population of China
CONCLUSION: Analyses showed that VOI was significantly associated with CVD. VOI is a simple and accurate prognostic marker of CVD risk, which has the potential ability to improve the risk stratification of CVD.PMID:36567914 | PMC:PMC9771649 | DOI:10.1155/2022/5289122
Source: Biomed Res - December 26, 2022 Category: Research Authors: Chang Wang Chuning Shi Songyue Liu Danxi Geng Yingxian Sun Source Type: research

Cost-effectiveness analysis of autogenous arteriovenous fistula, arteriovenous graft, and tunneled-cuffed catheter for hemodialysis in patients with end-stage kidney disease in Southern China
CONCLUSION: These findings illustrate the value of AVF given its relative cost-effectiveness to other hemodialysis modalities. Although AVG costs much more than TCC for slightly higher QALYs than TCC, AVG still has a greater advantage over TCC for patients with longer life expectancy due to its lower probability of death.PMID:36540049 | DOI:10.1177/11297298221143010
Source: The Journal of Vascular Access - December 21, 2022 Category: Surgery Authors: Tak-Sui Wong Qian Chen Qiongqiong Zhong Bo Hu Guanrui Feng Fengqiu Huang Jian Lu Lianghong Yin Zongchao Yu Babatunde O Akinwunmi Jian Huang Casper Jp Zhang Wai-Kit Ming Source Type: research

Use of the Vascular Overload Index to Predict Cardiovascular Disease in a Rural Population of China
CONCLUSION: Analyses showed that VOI was significantly associated with CVD. VOI is a simple and accurate prognostic marker of CVD risk, which has the potential ability to improve the risk stratification of CVD.PMID:36567914 | PMC:PMC9771649 | DOI:10.1155/2022/5289122
Source: Biomed Res - December 26, 2022 Category: Research Authors: Chang Wang Chuning Shi Songyue Liu Danxi Geng Yingxian Sun Source Type: research