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Total 26889 results found since Jan 2013.
Beta-blockers in pulmonary arterial hypertension: Time for a second thought?
Vascul Pharmacol. 2022 Mar 4;144:106974. doi: 10.1016/j.vph.2022.106974. Online ahead of print.ABSTRACTPulmonary arterial hypertension (PAH) is a heart failure syndrome characterized by right ventricular (RV) to pulmonary circulation uncoupling, counteracted by the sympathetic nervous system activation leading to β1-receptors and α-myosin heavy chain downregulation, downregulation of the sarcoplasmic reticulum Ca2+ATPase, and β-myosin heavy chain upregulation. Increased ventilation (VE) associated with VE inefficiency further characterizes PAH, as shown by an elevated VE versus carbon dioxide relationship slope during e...
Source: Vascular Pharmacology - March 6, 2022 Category: Drugs & Pharmacology Authors: R Badagliacca V Mercurio E Romeo M Correale D Masarone S Papa C G Tocchetti P Agostoni Members of the Study Group on Right and Left Heart Failure of the Italian Society of Cardiology Source Type: research
Correction
In the March 2022 issue of the Journal of Vascular Surgery, the article by Arbabi et al (Arbabi CN, DuBose J, Starnes BW, Saqib N, Quiroga E, Miller C, et al. Outcomes of thoracic endovascular aortic repair in patients with concomitant blunt thoracic aortic injury and traumatic brain injury from the Aortic Trauma Foundation global registry. J Vasc Surg 2022;75:930-8) omitted two collaborators from the original published version. The two additional collaborators are Mario D'Oria, MD, and Sandro Lepidi, MD, from University Hospital of Trieste, Italy.
Source: Journal of Vascular Surgery - May 19, 2022 Category: Surgery Tags: Correction Source Type: research
Guidelines on the management of abdominal aortic aneurysms: updates from the Italian Society of Vascular and Endovascular Surgery (SICVE)
The objective of these Guidelines was to revise and update the previous 2016 Italian Guidelines on Abdominal Aortic Aneurysm Disease, in accordance with the National Guidelines System (SNLG), to guide every practitioner toward the most correct management pathway for this pathology. The methodology applied in this update was the GRADE-SIGN version methodology, following the instructions of the AGREE quality of reporting checklist as well. The first methodological step was the formulation of clinical questions structured according to the PICO (Population, Intervention, Comparison, Outcome) model according to which the Recomm...
Source: The Journal of Cardiovascular Surgery - June 6, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Carlo Pratesi Davide Esposito Dimitrios Apostolou Luca Attisani Raffaello Bellosta Filippo Benedetto Ilaria Blangetti Stefano Bonardelli Andrea Casini Aaron T Fargion Elisabetta Favaretto Antonio Freyrie Edoardo Frola Vittorio Miele Raffaella Niola Claudi Source Type: research
Telehealth: A winning weapon to face the COVID-19 outbreak for patients with pulmonary arterial hypertension
CONCLUSION: Italy was found unprepared to manage the dramatic effects caused by COVID-19 on healthcare systems. In this emergency situation telemedicine represented a promising tool especially in rare diseases as PAH, but was limited by its scattered availability and legal and ethical issues. Cohesive partnership of health care providers with regional public health officials is needed to prioritize PAH patients for telemedicine by dedicated tools.PMID:35716991 | DOI:10.1016/j.vph.2022.107024
Source: Vascular Pharmacology - June 18, 2022 Category: Drugs & Pharmacology Authors: Giovanna Manzi Silvia Papa Marco Valerio Mariani Gianmarco Scoccia Domenico Filomena Claudia Malerba Francesca Adamo Annalisa Caputo Claudio De Lazzari Beatrice De Lazzari Nadia Cedrone Rosalinda Madonna Tommaso Recchioni Giorgia Serino Carmine Dario Vizz Source Type: research
Risk of intraocular pressure increase with intravitreal injections of Vascular Endothelial Growth Factor Inhibitors: a cohort study
Intraocular pressure increase (IOPi) after intravitreal injections of vascular endothelial growth factor inhibitors (VEGFis) might be different between different VEGFi (bevacizumab, aflibercept, ranibizumab). The purpose of this study was to evaluate the risk of IOPi among new users of bevacizumab, ranibizumab, and aflibercept in non-diabetic patients in Tuscany, Italy.
Source: American Journal of Ophthalmology - November 17, 2022 Category: Opthalmology Authors: Andrea Spini, Sabrina Giometto, Sandra Donnini, Matteo Posarelli, Francesco Dotta, Marina Ziche, Gian Marco Tosi, Anna Girardi, Ersilia Lucenteforte, Rosa Gini, Mahyar Etminan, Gianni Virgili Tags: Original Articles Source Type: research
Use of bempedoic acid for LDL cholesterol lowering and cardiovascular risk reduction: a consensus document from the Italian study group on atherosclerosis, thrombosis and vascular biology
Vascul Pharmacol. 2022 Dec 1:107137. doi: 10.1016/j.vph.2022.107137. Online ahead of print.NO ABSTRACTPMID:36464086 | DOI:10.1016/j.vph.2022.107137
Source: Atherosclerosis - December 4, 2022 Category: Cardiology Authors: Giuseppe Patti Ilaria Cavallari Arturo Cesaro Felice Gragnano Letizia Riva Fabio Fimiani Claudio Cuccia Claudio Fresco Paolo Calabr ò Sergio Leonardi Rossella Marcucci Andrea Rubboli Source Type: research
Occupational accidents among search and rescue providers during mountain rescue operations and training events - Milani M, Roveri G, Falla M, Dal Cappello T, Strapazzon G.
STUDY OBJECTIVE: We analyzed occupational accidents reported among Corpo Nazionale Soccorso Alpino e Speleologico (CNSAS) providers during mountain search and rescue operations and training events in Italy (1999 to 2019). METHODS: We extracted anon...
Source: SafetyLit - January 23, 2023 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Long term respiratory morbidity in patients with vascular rings: a review
Abnormalities in position and/or branching of the aortic arch can lead to vascular rings that may cause narrowing of the tracheal lumen due to external compression, or constriction of the oesophagus, causing s...
Source: Italian Journal of Pediatrics - February 17, 2023 Category: Pediatrics Authors: Federica Porcaro, Paolo Ciliberti, Francesca Petreschi, Aurelio Secinaro, Annalisa Allegorico, Antonella Coretti and Renato Cutrera Tags: Review Source Type: research
Associations of a biopsychosocial frailty phenotype with all-cause dementia, Alzheimer ’s disease, vascular dementia, and other dementias: the Italian PRoject on the Epidemiology of Alzheimer’s disease (IPREA)
In conclusion, in a large cohort of Italian older individuals, a biopsychosocial frailty model was associated to all-cause dementia, probable AD, and probable and possible VaD. In the next future, other large and prospective population-based studies evaluating the association between the biopsychosocial frailty phenotype and incident all-cause dementia, AD, and VaD are needed, addressing also potential bias and confounding sources.
Source: AGE - April 4, 2023 Category: Geriatrics Source Type: research
Sacubitril/valsartan effects on arrhythmias and left ventricular remodelling in heart failure: An observational study
CONCLUSION: Sacubitril/valsartan reduced the number of premature ventricular complexes and increased the percentage of biventricular pacing in a cohort of HFrEF patients already on optimal medical therapy. PVC reduction did not correlate with reverse left ventricular remodelling. Whether sacubitril/valsartan has any direct antiarrhythmic effects is an issue to be better explored in future studies.PMID:37467909 | DOI:10.1016/j.vph.2023.107196
Source: Vascular Pharmacology - July 19, 2023 Category: Drugs & Pharmacology Authors: Mauro Acquaro Laura Scelsi Beatrice Pasotti Alessandro Seganti Marcello Spolverini Alessandra Greco Sandra Schirinzi Annalisa Turco Antonio Sanzo Simone Savastano Roberto Rordorf Stefano Ghio Source Type: research
