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Total 56441 results found since Jan 2013.

Vascular tight junction disruption and angiogenesis in spontaneously hypertensive rat with neuroinflammatory white matter injury.
Abstract Vascular cognitive impairment is a major cause of dementia caused by chronic hypoxia, producing progressive damage to white matter (WM) secondary to blood-brain barrier (BBB) opening and vascular dysfunction. Tight junction proteins (TJPs), which maintain BBB integrity, are lost in acute ischemia. Although angiogenesis is critical for neurovascular remodeling, less is known about its role in chronic hypoxia. To study the impact of TJP degradation and angiogenesis during pathological progression of WM damage, we used the spontaneously hypertensive/stroke prone rats with unilateral carotid artery occlusion ...
Source: Neurobiology of Disease - February 24, 2018 Category: Neurology Authors: Yang Y, Kimura-Ohba S, Thompson JF, Salayandia VM, Cosse M, Raz L, Jalal FY, Rosenberg GA Tags: Neurobiol Dis Source Type: research

Advances and Developments in Vascular Access in Japan.
This article describes recent advances and future directions in the field of vascular access in Japan. SUMMARY: In vascular access techniques using patients' own vessels, such as creating an internal shunt and superficialization of the brachial artery, management and monitoring to maintain healthy conditions is crucial. New materials composed of synthetic products, such as artificial blood vessels, catheters, and vessel-enlarging balloon catheters, are continuously under development, and the full range of use of these products as well as their mode of use to maximize their benefits are currently being studied. Key Mess...
Source: Contributions to Nephrology - July 26, 2018 Category: Urology & Nephrology Tags: Contrib Nephrol Source Type: research

Randomized phase II trial of the prophylactic use of celecoxib for the prevention of oxaliplatin-related peripheral vascular pain in Capeox (YCOG1205)
ConclusionsCelecoxib was unable to prevent oxaliplatin-related vascular pain in this study. However, it may be able to decrease the vascular pain that patients already have.
Source: Cancer Chemotherapy and Pharmacology - December 6, 2018 Category: Cancer & Oncology Source Type: research

Successful bailout procedure for acute popliteal artery occlusion associated with EXOSEAL ® vascular closure device: a case report
ConclusionAcute limb ischemia caused by an EXOSEAL vascular closure device is a very rare complication. Balloon angioplasty and stenting are considered to be effective options to deal with the plug dislodgement of an EXOSEAL vascular closure device. We must be prepared for every rare complication during endovascular treatment.
Source: Journal of Medical Case Reports - March 20, 2019 Category: General Medicine Source Type: research

Assessment of macular vascular plexus density using optical coherence tomography angiography in cases of strabismic amblyopia
Conclusion: The superficial retinal vascular plexus density of a 4.5 × 4.5 mm cube centered at the fovea of eyes of cases of strabismic amblyopia is similar to that of normal eyes.
Source: Indian Journal of Ophthalmology - March 21, 2019 Category: Opthalmology Authors: Amar Pujari Rohan Chawla Ritika Mukhija Hameed Obedulla Swati Phuljhele Rohit Saxena Pradeep Sharma Atul Kumar Source Type: research

Arterial Stiffness and Endothelial Function in Young Obese Patients - Vascular Resistance Matters.
CONCLUSION: Our results indicate that both indices used for the detection of early atherosclerotic changes are influenced by vascular tone. Vascular resistance could influence CAVI and RHI results impairing their interpretation. PMID: 30930343 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - April 2, 2019 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Learning Curve Analysis to Determine Operative Requirements for Young Vascular Surgeons Learning Open Abdominal Aortic Aneurysm Repair.
CONCLUSIONS: Young vascular surgeons can safely learn open AAA repair without increasing operation time or complications. Approximately 30 cases would be necessary to gain satisfactory surgical skills. PMID: 31353341 [PubMed - as supplied by publisher]
Source: Circulation Journal - July 26, 2019 Category: Cardiology Authors: Shirasu T, Furuya T, Nagai M, Nomura Y Tags: Circ J Source Type: research

Neuro-vascular Interactions during Neocortical Development-Systematic and Accurate Regulatory Mechanisms of VEGF Signaling.
Abstract Blood vessels supply oxygen and nutrients to all the cells in a living body, and provide essential transport routes for collecting waste products. For these functions, blood vessel networks should be appropriately formed in each tissue. Therefore, blood vessels are one of the earliest organs formed during the developmental process. Development of the blood vessel system promotes tissue differentiation and organ morphogenesis, allowing each organ to maintain its unique functions under changing metabolic conditions. Blood vessels have a relatively simple structure, consisting of endothelial cells covering t...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 4, 2020 Category: Drugs & Pharmacology Authors: Mizutani KI Tags: Yakugaku Zasshi Source Type: research

Clinical and Radiological Comparison of Single and Double Intra-articular Injection of Adipose-Derived Stromal Vascular Fraction for Knee Osteoarthritis
In conclusion, double injections may provide more satisfactory treatment outcomes in patients with severe varus knee alignment. This clinical trial is registered in the Japanese Ministry of Health, Labour and Welfare (URL: https://saiseiiryo.mhlw.go.jp/published_plan/index/2) with the registration name "Cell transplantation therapy for osteoarthritis using autologous subcutaneous adipose tissue-derived regenerative (stem) cells (ADRCs)," and the registration number was "PB5160012."PMID:37551027 | PMC:PMC10411282 | DOI:10.1177/09636897231190175
Source: Cell Transplantation - August 8, 2023 Category: Cytology Authors: Masahiro Fujita Tomoyuki Matsumoto Satoshi Sobajima Masanori Tsubosaka Takehiko Matsushita Hideki Iwaguro Ryosuke Kuroda Source Type: research