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Drug: Metformin

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Total 2318 results found since Jan 2013.

Visualizing the effects of metformin on tumor growth, vascularity, and metabolism in head and neck cancer
Journal of Oral Pathology&Medicine, EarlyView.
Source: Journal of Oral Pathology and Medicine - April 10, 2018 Category: Pathology Authors: Aparajita Verma , Laurie J. Rich , Vui King Vincent ‐Chong , Mukund Seshadri Source Type: research

Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial
Diabetic Medicine, EarlyView.
Source: Diabetic Medicine - May 2, 2018 Category: Endocrinology Authors: N. Safai , T. Suvitaival , A. Ali , P. Sp égel , M. Al‐Majdoub , B. Carstensen , H. Vestergaard , M. Ridderstråle , on behalf of , L. Lundby‐Christensen , L. Tarnow , T. W. Boesgaard , S. S. Lund , N. Wiinberg , H. Source Type: research

Metformin's antitumour and anti ‐angiogenic activities are mediated by skewing macrophage polarization
Journal of Cellular and Molecular Medicine, EarlyView.
Source: Journal of Cellular and Molecular Medicine - May 4, 2018 Category: Molecular Biology Authors: Ji ‐Chang Wang , Xin Sun , Qiang Ma , Gui‐Feng Fu , Long‐Long Cong , Hong Zhang , De‐Fu Fan , Jun Feng , Shao‐Ying Lu , Jian‐Lin Liu , Guang‐Yue Li , Pei‐Jun Liu Source Type: research

The AMPK agonist 5 ‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting
EMBO Molecular Medicine, EarlyView.
Source: EMBO Molecular Medicine - May 29, 2018 Category: Molecular Biology Authors: Derek T Hall , Takla Griss , Jennifer F Ma , Brenda Janice Sanchez , Jason Sadek , Anne Marie K Tremblay , Souad Mubaid , Amr Omer , Rebecca J Ford , Nathalie Bedard , Arnim Pause , Simon S Wing , Sergio Di Marco , Gregory R Stei Source Type: research

Perioperative management of adult diabetic patients. Preoperative period
Publication date: June 2018 Source:Anaesthesia Critical Care & Pain Medicine, Volume 37, Supplement 1 Author(s): Gaëlle Cheisson, Sophie Jacqueminet, Emmanuel Cosson, Carole Ichai, Anne-Marie Leguerrier, Bogdan Nicolescu-Catargi, Alexandre Ouattara, Igor Tauveron, Paul Valensi, Dan Benhamou In diabetic patients undergoing surgery, we recommend assessing glycaemic control preoperatively by assessing glycated haemoglobin (HbA1c) levels and recent capillary blood sugar (glucose) levels, and to adjust any treatments accordingly before surgery, paying particular attention to specific complications of diabetes. Gastrop...
Source: Anaesthesia, Critical Care and Pain Medicine - June 19, 2018 Category: Anesthesiology Source Type: research

In vitro and in vivo investigation of PLA/PCL scaffold coated with metformin-loaded gelatin nanocarriers in regeneration of critical-sized bone defects
Publication date: Available online 28 June 2018 Source:Nanomedicine: Nanotechnology, Biology and Medicine Author(s): Mostafa Shahrezaee, Majid Salehi, Sara Keshtkari, Ahmad Oryan, Amir Kamali, Babak Shekarchi Large bone defects constitute a major challenge in bone tissue engineering and usually fail to heal due to the incomplete differentiation of recruited mesenchymal stem cells (MSCs) into osteogenic precursor cells. As previously proposed, metformin (MET) induces differentiation of MSCs into osteoblastic lineages in vitro. We fabricated a Poly (lactic acid) and Polycaprolactone (PLA/PCL) scaffold to deliver metformin l...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - June 29, 2018 Category: Nanotechnology Source Type: research

Pharmacological therapy selection of type 2 diabetes based on the SWARA and modified MULTIMOORA methods under a fuzzy environment
Publication date: May 2018Source: Artificial Intelligence in Medicine, Volume 87Author(s): M. Eghbali-Zarch, R. Tavakkoli-Moghaddam, F. Esfahanian, M.M. Sepehri, A. AzaronAbstractMedication selection for Type 2 Diabetes (T2D) is a challenging medical decision-making problem involving multiple medications that can be prescribed to control the patient’s blood glucose. The wide range of hyperglycemia lowering agents with varying effects and various side effects makes the decision quite difficult. This paper presents computer-aided medical decision support using a fuzzy Multi-Criteria Decision-Making (MCDM) model that hybrid...
Source: Artificial Intelligence in Medicine - July 5, 2018 Category: Bioinformatics Source Type: research

Punica granatum improves renal function in gentamicin-induced nephropathy in rats via attenuation of oxidative stress
ConclusionData suggests that MPGL attenuated oxidative stress associated renal injury by preserving antioxidant enzymes, reducing lipid peroxidation and inhibiting inflammatory mediators such as TNF-α.Graphical abstract
Source: Journal of Ayurveda and Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Pharmacological therapy selection of type 2 diabetes based on the SWARA and modified MULTIMOORA methods under a fuzzy environment
Publication date: May 2018Source: Artificial Intelligence in Medicine, Volume 87Author(s): M. Eghbali-Zarch, R. Tavakkoli-Moghaddam, F. Esfahanian, M.M. Sepehri, A. AzaronAbstractMedication selection for Type 2 Diabetes (T2D) is a challenging medical decision-making problem involving multiple medications that can be prescribed to control the patient’s blood glucose. The wide range of hyperglycemia lowering agents with varying effects and various side effects makes the decision quite difficult. This paper presents computer-aided medical decision support using a fuzzy Multi-Criteria Decision-Making (MCDM) model that hybrid...
Source: Artificial Intelligence in Medicine - July 10, 2018 Category: Bioinformatics Source Type: research

Punica granatum improves renal function in gentamicin-induced nephropathy in rats via attenuation of oxidative stress
ConclusionData suggests that MPGL attenuated oxidative stress associated renal injury by preserving antioxidant enzymes, reducing lipid peroxidation and inhibiting inflammatory mediators such as TNF-α.Graphical abstract
Source: Journal of Ayurveda and Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research

Medicines for Treatment Intensification in Type 2 Diabetes and Type of Insulin in Type 1 and Type 2 Diabetes in Low-Resource Settings: Synopsis of the World Health Organization Guidelines on Second- and Third-Line Medicines and Type of Insulin for the Control of Blood Glucose Levels in Nonpregnant Adults With Diabetes Mellitus.
Abstract Description: The World Health Organization developed these guidelines to provide guidance on selection of medicines for treatment intensification in type 2 diabetes and on use of insulin (human or analogue) in type 1 and 2 diabetes. The target audience includes clinicians, policymakers, national diabetes program managers, and medicine procurement officers. The target population is adults with type 1 or 2 diabetes in low-resource settings in low- or high-income countries. The guidelines also apply to disadvantaged populations in high-income countries. Methods: The recommendations were formulated by a ...
Source: Annals of Internal Medicine - September 4, 2018 Category: Internal Medicine Authors: Roglic G, Norris SL Tags: Ann Intern Med Source Type: research

Review of Metformin Use for Type 2 Diabetes Prevention
Publication date: October 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 4Author(s): Tannaz Moin, Julie A. Schmittdiel, James H. Flory, Jessica Yeh, Andrew J. Karter, Lydia E. Kruge, Dean Schillinger, Carol M. Mangione, William H. Herman, Elizabeth A. Walker
Source: American Journal of Preventive Medicine - September 18, 2018 Category: International Medicine & Public Health Source Type: research

"Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018": Antihyperglycemic Activity of Hamelia patens Jacq. Extracts.
Authors: Rugerio-Escalona C, Ordaz-Pichardo C, Becerra-Martinez E, Cruz-López MDC, López-Y-López VE, Mendieta-Moctezuma A, Maldonado-Mendoza IE, Jiménez-Montejo FE Abstract Diabetes is one the world's most widespread diseases, affecting over 327 million people and causing about 300,000 deaths annually. Despite great advances in prevention and therapy, existing treatments for this disorder have serious side effects. Plants used in traditional medicine represent a valuable source in the search for new medicinal compounds. Hamelia patens Jacq. has been used for treating diabetes and, so far, no reports have been m...
Source: Evidence-based Complementary and Alternative Medicine - September 20, 2018 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Information for CME Credit-Review of Metformin Use for Type 2 Diabetes Prevention
Publication date: October 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 4Author(s):
Source: American Journal of Preventive Medicine - September 22, 2018 Category: International Medicine & Public Health Source Type: research

Metformin as an Antineoplastic Drug in Oral Squamous Cell Carcinoma Cultures in Vitro
Publication date: September 2018Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 126, Issue 3Author(s): Alexandre Scremin Czezacki, Marcelo Sperandio, Pollyanna Montaldi, Vera Cavalcanti De Araújo, Marcelo Napimoga, Paulo De Camargo Moraes, Victor Angelo Martins Montalli
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - October 5, 2018 Category: ENT & OMF Source Type: research