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Drug: Metformin

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Total 2318 results found since Jan 2013.

Discontinuing Metformin: The Crowdsourced View Discontinuing Metformin: The Crowdsourced View
Readers were divided on the decision to stop an elderly woman ' s metformin and reduce her pill burden.Medscape Family Medicine
Source: Medscape FamilyMedicine Headlines - June 23, 2021 Category: Primary Care Tags: Family Medicine/Primary Care Article Source Type: news

Effects of Berberine on Diabetes and Cognitive Impairment in an Animal Model: The Mechanisms of Action
In this study, a STZ diabetes rat model feeding with a high-fat diet was used to test the effects of berberine compared with metformin. Oral glucose tolerance and hyperinsulinemic-euglycemic clamp were used for glucose metabolism and insulin resistance. The Morris water maze was used to observe the compound effects on cognitive impairment. Serum and hippocampal [Formula: see text]-amyloid peptide (A[Formula: see text], Tau and phosphorylated Tau protein deposition in the hippocampi were measured. The TUNEL assay was used to detect the neuronal apoptosis, supported by histomorphological changes and transmissional electron m...
Source: The American Journal of Chinese Medicine - June 17, 2021 Category: Complementary Medicine Authors: Jing-Hua Zhang Jin-Feng Zhang Jun Song Yu Bai Lan Deng Chun-Peng Feng Xin-Yao Xu Hong-Xia Guo Yi Wang Xin Gao Yan Gu Chuan Jin Jun-Fu Zheng Zhong Zhen Hao Su Source Type: research

Development and Validation of a Simple and Sensitive LC-MS/MS Method for Quantification of Metformin in Dried Blood Spot Its Application as an Indicator for Medication Adherence
Source: International Journal of General Medicine - July 8, 2021 Category: General Medicine Tags: International Journal of General Medicine Source Type: research

Pharmacological Management of Diabetes Mellitus: A Century of Expert Opinions in Cecil Textbook of Medicine
Conclusions: The pharmacological management of DM has progressed unevenly, with a long latency period in the second half of the last century followed by highly encouraging advances in the first 2 decades of the 21st century. In chronological order, the major advances were synthetic insulins obtained through DNA recombinant technology, adoption of metformin as first line therapy, and introduction of antidiabetic medication classes that also promote weight reduction and cardiovascular health.
Source: American Journal of Therapeutics - July 1, 2021 Category: Drugs & Pharmacology Tags: Original Investigations Source Type: research

The Effects of < em > Berberis integerrima < /em > Fruit Extract on Glycemic Control Parameters in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Clinical Trial
CONCLUSION: Consumption of B. integerrima Bunge fruit extract at a dosage of 1000 mg daily decreases FBS and HbA1c but does not affect HOMA-IR in patients with type 2 diabetes mellitus.PMID:34285701 | PMC:PMC8275404 | DOI:10.1155/2021/5583691
Source: Evidence-based Complementary and Alternative Medicine - July 21, 2021 Category: Complementary Medicine Authors: Rasool Soltani Syed Mustafa Ghanadian Bijan Iraj Alireza Homayouni Tanin Shahmiveh Esfahani Mojtaba Akbari Source Type: research

Diabetes Monotherapies versus Metformin-Based Combination Therapy for the Treatment of Type 2 Diabetes
Source: International Journal of General Medicine - July 23, 2021 Category: General Medicine Tags: International Journal of General Medicine Source Type: research