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Drug: Metformin
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In vitro and in vivo antidiabetic effect of extracts of Melia azedarach, Zanthoxylum alatum, and Tanacetum nubigenum
ConclusionThis study demonstrated that these plants have a significant therapeutic value in type-2-diabetes mellitus and related complications thus supporting their traditional uses in Indian traditional system of medicine.Graphical abstract
Source: Integrative Medicine Research - July 10, 2018 Category: Complementary Medicine Source Type: research
A nutraceutical combination of Cinnamomum cassia & Nigella sativa for Type 1 diabetes mellitus
ConclusionThis study generates evidence to support Nigella sativa & Cinnamomum cassia as an adjunctive in diabetes treatment protocols.
Source: Journal of Ayurveda and Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Metformin reduces prostate cancer risk among men with benign prostatic hyperplasia: A nationwide population ‐based cohort study
In conclusion, both metformin medication and TCM use could be associated with reduced risk of prostate cancer for men with BPH and diabetes.
Source: Cancer Medicine - April 8, 2019 Category: Cancer & Oncology Authors: Yu ‐Jui Kuo,
Fung‐Chang Sung,
Po‐Fan Hsieh,
Hui‐Ping Chang,
Kun‐Ling Wu,
Hsi‐Chin Wu Tags: ORIGINAL RESEARCH Source Type: research
Comparative Antidiabetic Activity of Aqueous, Ethanol, and Methanol Leaf Extracts of Persea americana and Their Effectiveness in Type 2 Diabetic Rats.
Authors: Kouamé NM, Koffi C, N'Zoué KS, Yao NAR, Doukouré B, Kamagaté M
Abstract
Native to Mexico, Persea americana Mill. (avocado) is a fruit tree whose different parts (leaf, bark, roots, and stone) are used in traditional medicine especially against diabetes mellitus. The aim of this study was to investigate the beneficial effects of 28-day treatment with aqueous, ethanolic, and methanolic leaf extracts on glucose homeostasis in type 2 diabetic mellitus using Wistar rats. Type 2 diabetes was induced with nicotinamide (120 mg/kg, i.p.) and streptozotocin (65 mg/kg, i.p.). After 28 days of treatment, histo...
Source: Evidence-based Complementary and Alternative Medicine - November 20, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Clinical effects of Shou-Wu Jiang-Qi Decoction combined acupuncture on the treatment of Polycystic Ovarian Syndrome with kidney deficiency, phlegm and blood stasisness: Study protocol clinical trial (SPIRIT Compliant)
This study aims to examine the efficacy and safety of the combination of SWJQD and acupuncture in the treatment of PCOS.
Methods:
This randomized controlled trial will be conducted with a total of 81 participants diagnosed with PCOS. The participants will be randomly divided into 3 treatment groups: group A will receive SWJQD combined with acupuncture; group B, SWJQD combined with sham acupuncture; and group C, metformin. Each treatment will last 3 months. The primary outcomes include the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) index and the Oral Glucose Tolerance Test. The secondary outcome measure...
Source: Medicine - March 1, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Use of Common Meds Tied to Lower Lung Cancer Mortality
Combined use of aspirin, statins, metformin tied to lower lung cancer risk and mortality
Source: Pulmonary Medicine News - Doctors Lounge - October 17, 2020 Category: Respiratory Medicine Tags: Cardiology, Endocrinology, Family Medicine, Internal Medicine, Oncology, Pharmacy, Pulmonology, Journal, Source Type: news
Metformin Use May Reduce Mortality in Women With COVID - 19
In overall sample of men and women, metformin use was not linked to significantly reduced mortality
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Endocrinology, Gynecology, Infections, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pharmacy, Pulmonology, Journal, Source Type: news
Metformin Use for T2DM May Reduce COVID - 19 Mortality
Odds of contracting COVID - 19, COVID - 19 - related mortality higher for individuals with diabetes
Source: Pulmonary Medicine News - Doctors Lounge - January 27, 2021 Category: Respiratory Medicine Tags: Endocrinology, Family Medicine, Geriatrics, Gynecology, Infections, Internal Medicine, Critical Care, Nursing, Pharmacy, Pulmonology, Journal, Source Type: news
Predictors of Death, Discharge ID ’ d for Diabetes Patients With COVID - 19
Younger age, routine metformin therapy, and longer symptom duration on admission positively linked to discharge
Source: Pulmonary Medicine News - Doctors Lounge - February 23, 2021 Category: Respiratory Medicine Tags: Endocrinology, Infections, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pharmacy, Pulmonology, Geriatrics, Journal, Source Type: news
Sodium-Glucose Cotransporter 2 Inhibitors vs Sulfonylureas —The Price of Prevention
The number of different medications available to treat patients with type 2 diabetes has increased dramatically over the past 2 decades. While metformin remains the mainstay of initial treatment, there is ongoing debate regarding the optimal choice when adding a second oral agent. In this issue of JAMA Internal Medicine, Xie et al examine the comparative effectiveness of sodium-glucose cotransporter 2 (SGLT2) inhibitors vs sulfonylureas on all-cause mortality among metformin users. This high-dimensional propensity score –matched cohort study observed patients enrolled in the Veterans Affairs health system who were receiv...
Source: JAMA Internal Medicine - June 28, 2021 Category: Internal Medicine Source Type: research
Corrigendum Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel ‑7402/5‑fluorouracil cells
Mol Med Rep. 2022 May;25(5):175. doi: 10.3892/mmr.2022.12691. Epub 2022 Mar 22.ABSTRACTSubsequently to the publication of the above paper, the authors have reviewed its content and the primary data, and have realized that the western blots selected to show the β‑actin experiments featured in Fig. 4A and Fig. 3C were the same blot, albeit with a different exposure time. The control blots correctly presented for Fig. 3C were inadvertently copied into Fig. 4A owing to an error made during the figure compilation process. The revised version of Fig. 4, containing the correct β‑actin blots for Fig. 4A, is shown below. Note...
Source: Molecular Medicine - March 22, 2022 Category: Molecular Biology Authors: Sunbin Ling Yu Tian Haiquan Zhang Kaiqi Jia Tingting Feng Deguang Sun Zhenming Gao Fei Xu Zhaoyuan Hou Yan Li Liming Wang Source Type: research
Tangshen Decoction Enhances Podocytes Autophagy to Relieve Diabetic Nephropathy through Modulation of p-AMPK/p-ULK1 Signaling
Evid Based Complement Alternat Med. 2022 Apr 11;2022:3110854. doi: 10.1155/2022/3110854. eCollection 2022.ABSTRACTTraditional Chinese medicine has certain advantages in the prevention and treatment of diabetic nephropathy (DN); thus, Chinese medicine therapy is considered as a promising strategy for treating DN. Here, the diabetic nephropathy model was established and intervened with Tangshen Decoction to explore its repair effect on diabetic kidney injury and the mechanism of autophagy. Different doses (10, 20 g·kg-1) of Tangshen Decoction (so-called Tangshen Jian, TSJ) or metformin were used to intervene for 16 weeks. T...
Source: Evidence-based Complementary and Alternative Medicine - April 22, 2022 Category: Complementary Medicine Authors: Ling Yan Xiaoxiao Xu Yanbo Fan Lifang Zhang Xiaojing Niu Aimin Hu Source Type: research
