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New approaches for managing antiphospholipid syndrome
Nat Clin Pract Rheumatol. 2009 Mar;5(3):160-70. doi: 10.1038/ncprheum1017.ABSTRACTAntiphospholipid antibodies (aPL) are a family of autoantibodies directed against phospholipid-binding plasma proteins, most commonly beta(2)-glycoprotein-I. Primary thrombosis prevention in persistently aPL-positive individuals requires a risk-stratified approach; elimination of reversible thrombosis risk factors and aggressive prophylaxis during high-risk periods are crucial. The effectiveness of aspirin in persistently aPL-positive patients without vascular involvement is not supported by data from prospective, controlled studies. For the ...
Source: Nature Clinical Practice. Rheumatology. - March 3, 2009 Category: Rheumatology Authors: Doruk Erkan Michael D Lockshin Source Type: research
