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Drug: Amitriptyline
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Total 68 results found since Jan 2013.
Fibromyalgia: Diagnosis and Management
Am Fam Physician. 2023 Feb;107(2):137-144.ABSTRACTFibromyalgia is a chronic, centralized pain syndrome characterized by disordered processing of painful stimuli. Fibromyalgia is diagnosed more frequently in women and occurs globally, affecting 2% of people in the United States. Patients with fibromyalgia have diffuse chronic pain, poor sleep, fatigue, cognitive dysfunction, and mood disturbances. Comorbid conditions, such as functional somatic syndromes, psychiatric diagnoses, and rheumatologic conditions may be present. The Fibromyalgia Rapid Screening Tool is a helpful screening method for patients with diffuse chronic p...
Source: American Family Physician - February 15, 2023 Category: Primary Care Authors: Bradford T Winslow Carmen Vandal Laurel Dang Source Type: research
Analgesic Medication in Fibromyalgia Patients: A Cross-Sectional Study
Pain Res Manag. 2022 Sep 22;2022:1217717. doi: 10.1155/2022/1217717. eCollection 2022.ABSTRACTThere is no approved drug for fibromyalgia syndrome (FMS) in Europe. In the German S3 guideline, amitriptyline, duloxetine, and pregabalin are recommended for temporary use. The aim of this study was to cross-sectionally investigate the current practice of medication in FMS patients in Germany. We systematically interviewed 156 patients with FMS, while they were participating in a larger study. The patients had been stratified into subgroups with and without a decrease in intraepidermal nerve fiber density. The drugs most commonly...
Source: Pain Research and Management - October 17, 2022 Category: Anesthesiology Authors: H-C Aster D Evdokimov A Braun N Üçeyler C Sommer Source Type: research
In fibromyalgia, amitriptyline is comparable to FDA-approved drugs for symptoms and acceptability
Ann Intern Med. 2022 Oct 4. doi: 10.7326/J22-0071. Online ahead of print.ABSTRACTFarag HM, Yunusa I, Goswami H, et al. Comparison of amitriptyline and US Food and Drug Administration-approved treatments for fibromyalgia: a systematic review and network meta-analysis. JAMA Netw Open. 2022;5:e2212939. 35587348.PMID:36191311 | DOI:10.7326/J22-0071
Source: Annals of Internal Medicine - October 3, 2022 Category: Internal Medicine Authors: Roland Staud Source Type: research
Systematic Review and Meta-analysis Seem to Indicate that Cannabinoids for Chronic Primary Pain Treatment Have Limited Benefit
ConclusionCannabinoid treatment in patients with CPP had limited benefit on pain relief; however, it might improve pain with long-term administration.
Source: Pain and Therapy - September 21, 2022 Category: Anesthesiology Source Type: research
Comparative efficacy of amitriptyline, duloxetine and pregabalin for treating fibromyalgia in adults: an overview with network meta-analysis
This study included systematic reviews (SR) of randomized clinical trials (RCTs) targeting adult patients over 18 years of age diagnosed with fibromyalgia according to the criteria of scientific societies, which include the basic clinical diagnosis characterized by the presence of pressure sensitivity in at least 11 of the 18 tender points, in addition to the presence of widespread musculoskeletal pain for a period longer than 3 months and a general assessment of the patient’s health status. Pregnant women and children or adolescents were excluded. The Rob 2.0 tool from the Cochrane Collaboration was used to assess th...
Source: Clinical Rheumatology - June 18, 2022 Category: Rheumatology Source Type: research
Pharmacological management of fibromyalgia: a Bayesian network meta-analysis
Expert Rev Clin Pharmacol. 2022 Feb 19. doi: 10.1080/17512433.2022.2044792. Online ahead of print.ABSTRACTINTRODUCTION: The identification of the most effective therapy for patients with fibromyalgia (FM) remains controversial. Thus, we conducted a Bayesian network meta-analysis to compare several drugs employed as pharmacological management for FM.AREAS COVERED: The following databases were accessed in October 2021: PubMed, Google Scholar, Embase, and Scopus. All the randomized clinical trials (RCTs) that compare two or more pharmacological management for fibromyalgia were accessed. Only studies involving a minimum of 10 ...
Source: Pharmacological Reviews - February 21, 2022 Category: Drugs & Pharmacology Authors: Filippo Migliorini Nicola Maffulli J örg Eschweiler Matthias Knobe Markus Tingart Giorgia Colarossi Source Type: research
