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Total 2344 results found since Jan 2013.
A suggested protocol for value assignment using isotope-dilution-LC-MS/MS in reference measurement procedures - exemplary application for ciprofloxacin in serum
CONCLUSION: A standardized, detailed procedure for the application of isotope dilution LC-MS/MS in reference measurement procedures can complement the ISO 15193 standard with respect to this particular analytical technique, which is now widely used in the context of metrological traceability in laboratory medicine.PMID:37709112 | DOI:10.1016/j.cca.2023.117556
Source: International Journal of Clinical Chemistry - September 14, 2023 Category: Chemistry Authors: Judith Sch äffler Katharina Habler Michael Vogeser Source Type: research
Antimicrobial Potential of Cocos nucifera (Coconut) Oil on Bacterial Isolates
This study investigates the in vitro antibacterial activity of coconut oil on selected clinical and pure bacterial isolates. Clinical samples were isolated from the people of Ras Al Khaimah, United Arab Emirates. Biochemical examination of the microorganisms was done according to standard methods. Pure bacterial cultures were provided from LTA srl Italia. In this research work, an effort has been made to highlight the valuable properties of Cocos nucifera oil, in order to rationalize the use of coconut oil against bacteria. Experiments were performed by agar well diffusion method. Ciprofloxacin was used as a standard antib...
Source: Advances in Experimental Medicine and Biology - August 18, 2023 Category: Research Authors: Vibha Bhardwaj Source Type: research
What are Common Pitfalls in Measuring the QTc in Hospitalized Adult Patients?
Case
Ms. S. is a 60-year-old woman admitted with gastroenteritis and hypovolemia in the setting of three days of nausea and diarrhea. She was also found to have atrial fibrillation with rapid ventricular response. Her tachycardia improved after intravenous fluids. The following morning, nausea prompted her nurse to request antiemetic medications. You inspect the admission electrocardiogram (ECG) (Figure 1). Are QT-prolonging antiemetics safe to administer?
In this review, we provide background and practical guidance regarding QT interval (QTc) interpretation for the internist caring for hospitalized adults.
Accurate meas...
Source: The Hospitalist - August 1, 2023 Category: Hospital Management Authors: Ronda Whitaker Tags: Clinical Guidelines Key Clinical Questions Source Type: research
Paediatric medicine issues and gaps from healthcare workers point of view: survey results and a narrative review from the global accelerator for paediatric formulations project
The WHO Model List of Essential Medicines for Children (EMLc) has not been systematically revised in the last few years. We conducted a survey addressed to healthcare professionals prescribing, preparing, or administering medicines to children and a narrative review to identify problematic paediatric formulations or missing medicines in all therapeutic fields to inform the review of the EMLc in 2023. A total of 285 physicians (63%), 28 nurses (6%) and 142 pharmacists (31%), mostly working in the hospital setting, reported at least one problematic medicine. 290 medicines were reported as missing (completely or the child-app...
Source: Frontiers in Pharmacology - July 17, 2023 Category: Drugs & Pharmacology Source Type: research
Vaccination Is the Best Bet Against Drug-Resistant Superbugs — Experts
Experts encourage parents to vaccinate their children against typhoid to ensure that the child has access to clean drinking water. Credit: Zofeen Ebrahim/IPS By Zofeen EbrahimKARACHI, Jul 6 2023 (IPS) The first thing you notice about eight-month-old Manahil Zeeshan is how tiny she looks on the adult-size hospital bed at the government-run Sindh Institute of Child Health and Neonatology (SICHN) in Korangi, a neighbourhood in Karachi.
Her right foot is taped with a cannula, and she whimpers incessantly. “I have been in and out of the hospital for the last seven days,” said Uzma Mohammad, Zeeshan’s mom, with worry lines...
Source: IPS Inter Press Service - Health - July 6, 2023 Category: International Medicine & Public Health Authors: Zofeen Ebrahim Tags: Africa Civil Society Development & Aid Editors' Choice Featured Headlines Health Humanitarian Emergencies Inequality Poverty & SDGs TerraViva United Nations IPS UN Bureau IPS UN Bureau Report Pakistan Source Type: news
Case Report: Cedecea lapagei Infection: Report of a Case in Peru and Review of the Literature
This study aimed to describe a case report of C. lapagei in Peru and systematically review the documented case reports of individuals infected with C. lapagei. A 59-year-old man who had become bedridden with Parkinson's disease and had epilepsy presented with a 1-week history of fever and sore throat and was admitted. Physical examination revealed an obtundation state and abolished vesicular murmur in the right hemithorax. During hospitalization, the patient was diagnosed with various infections, including tuberculosis, for which he received broad-spectrum antibiotics. In the absence of clinical improvement, a urine cultur...
Source: The American Journal of Tropical Medicine and Hygiene - June 20, 2023 Category: Tropical Medicine Authors: Ali Al-Kassab-C órdova Patricia Valdiviezo-Polo Juan R Ulloque-Badaracco Carlos L Honorio-Arroyo Miguel Hueda-Zavaleta Vicente A Benites-Zapata Source Type: research
Experimentally exposed toxic effects of long-term exposure to environmentally relevant concentrations of CIP in males and females of the silver catfish Rhamdia quelen
This study aimed to evaluate the effects of long-term exposure to environmental CIP concentrations (1, 10, and 100 μg.L-1) in males and females of Rhamdia quelen. After 28 days of exposure, we collected the blood for the analysis of hematological and genotoxic biomarkers. Additionally, we measured 17 β-estradiol and 11 keto-testosterone levels. After the euthanasia, we collected the brain and the hypothalamus to analyze acetylcholinesterase (AChE) activity and neurotransmitters, respectively. The liver and gonads were assessed for biochemical, genotoxic, and histopathological biomarkers. At 100 μg.L-1 CIP, we observed g...
Source: Chemosphere - June 15, 2023 Category: Chemistry Authors: Lucicleide Ângelo Silva Jungles de Carvalho La ís Fernanda Oya-Silva Maiara Carolina Perussolo Gisele de Oliveira Guaita J úlio César Moreira Brito Allan Arnold Evans Maritana Mela Prodocimo Marta Margarete Cestari Tarcio Teodoro Bragah Helena Cristin Source Type: research
