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Total 2344 results found since Jan 2013.

Antimicrobial activity of Eucalyptus camaldulensis essential oils and their interactions with conventional antimicrobial agents against multi-drug resistant Acinetobacter baumannii
Conclusions The detected anti-A. baumannii activity of E. camaldulensis essential oils justifies traditional use of this plant. The proven E. camaldulensis essential oil synergistic interactions with conventional antibiotics could lead to the development of new treatment strategies of infections caused by MDR A. baumannii strains in the term of antibiotic dose reduction. Graphical abstract
Source: Journal of Ethnopharmacology - December 15, 2015 Category: Drugs & Pharmacology Source Type: research

Multidrug resistance and extended-spectrum β-lactamases genes among Escherichia coli from patients with urinary tract infections in Northwestern Libya.
CONCLUSION: The isolation of MDR ESBL-producing uropathogens undoubtedly will limit the choices clinicians have to treat their patients with UTIs. Therefore, there is an urgent need for surveillance studies on antimicrobial resistance and prevalence of ESBLs among uropathogens to guide the clinical treatment of UTIs in Libya in the future. PMID: 25651907 [PubMed - indexed for MEDLINE]
Source: Libyan Journal of Medicine - December 20, 2015 Category: Journals (General) Tags: Libyan J Med Source Type: research

Prevalence of the bla CTX-M-1 group and their transferability in resistant clinical isolates of Salmonella serogroups from several hospitals of Tehran.
CONCLUSION: This study demonstrates the predominant presence of the gene encoding CTX-M-1 group among ESBLs producing of Salmonella spp. They can transmit to bacteria of this genus or even other genera of enteric bacteria. PMID: 26697159 [PubMed]
Source: Iranian Journal of Microbiology - December 24, 2015 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Molecular characterization of virulence and antimicrobial susceptibility profiles of uropathogenic escherichia coli from patients in a tertiary hospital, southern thailand.
MOLECULAR CHARACTERIZATION OF VIRULENCE AND ANTIMICROBIAL SUSCEPTIBILITY PROFILES OF UROPATHOGENIC ESCHERICHIA COLI FROM PATIENTS IN A TERTIARY HOSPITAL, SOUTHERN THAILAND. Southeast Asian J Trop Med Public Health. 2015 Nov;46(6):1021-30 Authors: Themphachanal M, Kongpheng S, Rattanachuay P, Khianngam S, Singkhamanan K, Sukhumungoon P Abstract Among uropathogens, uropathogenic Escherichia coli (UPEC) is the most common cause of urinary tract infection (UTI) worldwide, but clinical aspects due to this bacterial species is not fully understood in southern Thailand. Two hundred fifty-four UPEC isolates fr...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - February 13, 2016 Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research

Extremely High Prevalence of Metronidazole-Resistant Helicobacter pylori Strains in Mountain People (Karen and Hmong) in Thailand.
This study aimed to survey the prevalence, patterns of antibiotic resistance, and clinical factors associated with antibiotic resistance in Helicobacter pylori among the Karen and Hmong mountain people of Thailand. We recruited dyspeptic patients in the Maesod district, Tak Province, Thailand. All subjects underwent upper gastrointestinal endoscopy, and three antral gastric biopsies were obtained for rapid urease tests and culture. An epsilometer was used to determine the minimum inhibitory concentrations of amoxicillin (AMX), clarithromycin (CLR), metronidazole (MNZ), levofloxacin (LVX), ciprofloxacin (CIP), and tetracycl...
Source: The American Journal of Tropical Medicine and Hygiene - February 15, 2016 Category: Tropical Medicine Authors: Vilaichone RK, Ratanachu-Ek T, Gamnarai P, Chaithongrat S, Uchida T, Yamaoka Y, Mahachai V Tags: Am J Trop Med Hyg Source Type: research

Properties and antimicrobial susceptibility of Trueperella pyogenes isolated from bovine mastitis in China.
Abstract Trueperella (T.) pyogenes is an opportunistic pathogen that causes suppurative diseases in domestic animals. In this work, the properties, pathogenesis and phenotypic diversity of T. pyogenes isolates from bovine mastitis were studied. Both pyolysin (plo) and collagen-binding protein (cbp) virulence factor genes were detected by PCR in all T. pyogenes isolates (n = 50). Using the tissue culture plate method, 90% of T. pyogenes isolates were able to form biofilms. The minimum inhibitory concentrations (MICs) of 13 antimicrobials against T. pyogenes isolates were determined. High susceptibility was observed...
Source: Acta Veterinaria Hungarica - February 28, 2016 Category: Veterinary Research Authors: Alkasir R, Wang J, Gao J, Ali T, Zhang L, Szenci O, Bajcsy ÁC, Han B Tags: Acta Vet Hung Source Type: research

Septicemia Caused by Neisseria meningitidis With Decreased Ciprofloxacin Susceptibility: The First Case Report in Korea.
Authors: Ahn JY, Min JK, Kim MH, Moon SY, Park KH, Lee MS, Son JS PMID: 26915621 [PubMed - in process]
Source: Annals of Laboratory Medicine - February 29, 2016 Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research

32nd International Austrian Winter Symposium
Table of contents A1 68Ga-PSMA PET/CT in staging and restaging of Prostate Cancer Patients: comparative study with 18F-Choline PET/CT W Langsteger, A Rezaee, W Loidl, HS Geinitz, F Fitz, M Steinmair, G Broinger, L Pallwien-Prettner, M Beheshti A2 F18 Choline PET – CT: an accurate diagnostic tool for the detection of parathyroid adenoma? L Imamovic, M Beheshti, G Rendl, D Hackl, O Tsybrovsky, M Steinmair, K Emmanuel, F Moinfar, C Pirich, W Langsteger A3 [18F]Fluoro-DOPA-PET/CT in the primary diagnosis of medullary thyroid carcinoma A Bytyqi, G Karanikas, M Mayerh...
Source: EJNMMI Research - April 17, 2016 Category: Radiology Source Type: research

Pharmacokinetic and pharmacodynamic evaluations of a 10 mg/kg enrofloxacin intramuscular administration in bearded dragons (Pogona vitticeps): a preliminary assessment
Enrofloxacin (E) is commonly used in veterinary medicine. It is necessary to perform pharmacokinetic/dynamic studies to minimize the selection of resistant mutants of bacteria and extend the efficacy of antimicrobial agents. Eight healthy adult Pogona vitticeps were assigned into two groups of equal size and treated with a single intramuscular injection of E at 10 mg/kg. Blood samples were withdrawn at different scheduled times for each group, and rectal swabs were collected. E and ciprofloxacin (active metabolite) blood concentrations were quantified by an HPLC validated method, while the in vitro antimicrobial suscepti...
Source: Journal of Veterinary Pharmacology and Therapeutics - April 28, 2016 Category: Veterinary Research Authors: M. Salvadori, C. Vercelli, V. De Vito, D. Dezzutto, S. Bergagna, G. Re, M. Giorgi Tags: Scientific Paper Source Type: research

Oral Fluoroquinolones and the Risk Of Uveitis
Previous studies have demonstrates that fluoroquinolones, and most notably ciprofloxacin and moxifloxacin may be associated with an increased risk of uveitis. The purpose of this study was to determine the association between oral fluoroquinolone and the risk of uveitis.
Source: The Journal of Emergency Medicine - April 30, 2016 Category: Emergency Medicine Authors: Jacob Nacht Source Type: research

Investigation of fluoroquinolone resistance mechanisms in clinical Acinetobacter baumannii isolates.
Authors: Güler G, Eraç B Abstract Acinetobacter baumannii is an opportunistic pathogen which is one of the most important agents of nosocomial infections. Being resistant to many antibiotics, complicates the treatment of the infections caused. Fluoroquinolones are used in the treatment of nosocomial and community-acquired infections and it is important to determine the mechanisms of resistance to these antibiotics. The aims of this study were to investigate ciprofloxacin (CIP) and levofloxacin (LEV) minimum inhibitor concentrations (MIC), clonal relationships, mutations that occur in DNA gyrase and topoisomerase ...
Source: Mikrobiyoloji Bulteni - May 17, 2016 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research

Investigation of plasmid-mediated quinolone resistance genes in quinolone-resistant Escherichia coli and Klebsiella spp. isolates from bloodstream infections.
Authors: Buruk CK, Öztel Ocak H, Bayramoğlu G, Aydın F Abstract One of the treatment options of Escherichia coli and Klebsiella spp. infections which are the most common opportunistic pathogens of gram-negative sepsis is quinolones. Resistance to quinolones which act by disrupting DNA synthesis has been increasing. Horizontal transfer of plasmid-mediated quinolone resistance (PMQR) genes play an important role in the spread of resistance. The data about the prevalence of PMQR genes in our country is quite limited. The aim of this study was to investigate the presence of known PMQR genes namely qnrA, qnrB, qnrC, ...
Source: Mikrobiyoloji Bulteni - May 17, 2016 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research

Combined Therapy With Adipose-Derived Mesenchymal Stem Cells and Ciprofloxacin Against Acute Urogenital Organ Damage in Rat Sepsis Syndrome Induced by Intrapelvic Injection of Cecal Bacteria
In conclusion, ADMSC-assisted ciprofloxacin therapy offered an additional benefit by reducing acute urogenital organ damage in rat. Significance Autologous adipose-derived mesenchymal stem cell-assisted ciprofloxacin therapy offered an additional benefit by reducing acute urogenital organ damage in rats.
Source: Stem Cells Translational Medicine - May 23, 2016 Category: Stem Cells Authors: Sung, P.-H., Chiang, H.-J., Chen, C.-H., Chen, Y.-L., Huang, T.-H., Zhen, Y.-Y., Chang, M.-W., Liu, C.-F., Chung, S.-Y., Chen, Y.-L., Chai, H.-T., Sun, C.-K., Yip, H.-K. Tags: Adipose-Derived Stem Cells, Standards, Policies, Protocols, and Regulations for Cell-Based Therapies Source Type: research

Hypersensitivity to fluoroquinolones: The expression of basophil activation markers depends on the clinical entity and the culprit fluoroquinolone
The objective of this study was to evaluate the influence of 2 different activations markers, CD63 and CD203c, on the sensitivity of BAT to FQ. We studied 17 patients with immediate allergic reactions to FQ. BAT was performed with moxifloxacin and ciprofloxacin using CD193 (CCR3) for basophil selection and CD203c or CD63 as activation markers. Stimulation with ciprofloxacin induced a significantly higher expression of CD63 in ciprofloxacin-allergic patients compared to moxifloxacin-allergic patients (P = 0.002). In patients allergic to moxifloxacin with anaphylactic shock, we have observed an increase in the percentage of ...
Source: Medicine - June 1, 2016 Category: Internal Medicine Tags: Research Article: Diagnostic Accuracy Study Source Type: research

Primary cellulitis and cutaneous abscess caused by Yersinia enterocolitica in an immunocompetent host: A case report and literature review
We report a case of primary cellulitis and cutaneous abscess caused by Y enterocolitica in an immunocompetent 70-year-old woman with keratodermia tylodes palmaris progressiva. She presented to an outpatient clinic with redness, swelling, and pain of the left ring finger and left upper arm without fever or gastrointestinal symptoms 3 days before admission. One day later, ulceration of the skin with exposed bone of the proximal interphalangeal joint of the left ring finger developed, and cefditoren pivoxil was described. However, she was admitted to our hospital due to deterioration of symptoms involving the left finger and ...
Source: Medicine - June 1, 2016 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research