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Drug: Cipro

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Total 2344 results found since Jan 2013.

Intravenous anti-MRSA phosphatiosomes mediate enhanced affinity to pulmonary surfactants for effective treatment of infectious pneumonia
Publication date: Available online 8 November 2017 Source:Nanomedicine: Nanotechnology, Biology and Medicine Author(s): Ching-Yun Hsu, Calvin T. Sung, Ibrahim A. Aljuffali, Chun-Han Chen, Kai-Yin Hu, Jia-You Fang The aim of this study was to develop PEGylated phosphatidylcholine (PC)-rich nanovesicles (phosphatiosomes) carrying ciprofloxacin (CIPX) for lung targeting to eradicate extracellular and intracellular methicillin-resistant Staphylococcus aureus (MRSA). Soyaethyl morphonium ethosulfate (SME) was intercalated in the nanovesicle surface with the dual goals of achieving strengthened bactericidal activity of CIPX-loa...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - November 9, 2017 Category: Nanotechnology Source Type: research

Antimicrobial resistance and underlying mechanisms in Staphylococcus aureus isolates
Conclusions In conclusion, it was determined that the isolates were resistant to different classes of antimicrobials at varying rates and resistance was mediated by different genetic mechanisms. Therefore, continuous monitoring of resistance in S . aureus strains is necessary to control their resistance for clinically important antimicrobials.
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Model Calculations of Regional Deposition and Disposition for Single Doses of Inhaled Liposomal and Dry Powder Ciprofloxacin
Journal of Aerosol Medicine and Pulmonary Drug Delivery,Volume 31, Issue 1, Page 49-60, February 2018.
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - February 1, 2018 Category: Respiratory Medicine Authors: Andrew R. Martin Warren H. Finlay Source Type: research

Quality Assessment of Some Essential Children's Medicines Sold in Licensed Outlets in Ashanti Region, Ghana.
Authors: Frimpong G, Ofori-Kwakye K, Kuntworbe N, Buabeng KO, Osei YA, Boakye-Gyasi ME, Adi-Dako O Abstract The quality of 68 samples of 15 different essential children's medicines sold in licensed medicine outlets in the Ashanti Region, Ghana, was evaluated. Thirty-two (47.1%) of the medicines were imported, mainly from India (65.6%) and the United Kingdom (28.1%), while 36 (52.9%) were locally manufactured. The quality of the medicines was assessed using content of active pharmaceutical ingredient (API), pH, and microbial limit tests, and the results were compared with pharmacopoeial standards. Twenty-six (38.2%)...
Source: Journal of Tropical Medicine - June 30, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Antibiotic-potentiating activity, phytochemical profile, and cytotoxicity of Acalypha integrifolia Willd. (Euphorbiaceae)
Publication date: March 2018Source: Journal of Herbal Medicine, Volume 11Author(s): Roumita Seebaluck-Sandoram, Namrita Lall, Bianca Fibrich, Analike Blom van Staden, Fawzi MahomoodallyAbstractAcalypha integrifolia Willd. (Euphorbiaceae) (AI), an indigenous medicinal plant of the Mascarene Islands is traditionally used to manage infectious diseases. The authors aimed to evaluate the antimicrobial, antibiotic-potentiating activity and cytotoxicity of AI. Decoction as traditionally used and organic extracts (hexane, dichloromethane, ethyl acetate, and methanol) of AI leaves were screened for their antimicrobial activity agai...
Source: Journal of Herbal Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

The dark side of antibiotic ciprofloxacin
(Baylor College of Medicine) Researchers have found that ciprofloxacin, a widely prescribed antibiotic, increases the risk of tears and rupture on the main artery of the body, the aorta, in a mouse model of human aortic aneurysms and dissections, a disease that carries high risk of death from aortic rupture.
Source: EurekAlert! - Medicine and Health - July 25, 2018 Category: International Medicine & Public Health Source Type: news

Antibiotic susceptibility of wound swab isolates in a tertiary hospital in Southwest Nigeria
Conclusion: Most of the microbial isolates, particularly the Gram-negative isolates demonstrated low sensitivity to commonly used antibiotics and moderate-to-high sensitivity to less commonly used newer antibiotics. Résumé Contexte: Les plaies sont généralement rencontrés dans la pratique clinique. La colonisation et l'infection Microbacterial négatif sur blessure Les résultats. Avec l'augmentation de l'émergence de souches résistantes aux antibiotiques, il est essentiel de d&...
Source: Annals of African Medicine - August 31, 2018 Category: African Health Authors: Eguono Erhinyaye Omoyibo Ayodeji Olarewaju Oladele Muhammad Habib Ibrahim Oluwakayode Temitope Adekunle Source Type: research

Clinical pattern and antibiotic sensitivity of bacterial corneal ulcers in Kano, Northern Nigeria
Conclusion: Ocular trauma was the major predisposing factor to corneal ulcer, and Staphylococcus species was the major bacterial organism isolated. Isolates were found to be sensitive to ciprofloxacin and ofloxacin, while an intermediate sensitivity was seen with chloramphenicol and gentamicin. Résumé But: Le but de cette étude est de déterminer les facteurs de prédisposition, les causes bactériennes courantes, et la sensibilité aux antibiotiques des ulcères de la cornée à l'hôpit...
Source: Annals of African Medicine - August 31, 2018 Category: African Health Authors: Usman Mijinyawa Abubakar Abdu Lawan Isyaku Muhammad Source Type: research

Mycobacterium goodii pneumonia: An unusual presentation of nontuberculous mycobacterial infection requiring a novel multidisciplinary approach to management
ConclusionsThis is an unusual case of organizing pneumonia related to Mycobacterium goodii infection and highlights the importance of mycobacterial culture in unusual and unresolving cases of organizing pneumonia. The importance of controlling symptoms related to gastric dysmotility and aspiration is also addressed.
Source: Respiratory Medicine Case Reports - March 1, 2019 Category: Respiratory Medicine Source Type: research

Ciprofloxacin Dry Powder for Inhalation: Inspiratory Flow in Patients with Non-cystic Fibrosis Bronchiectasis
Journal of Aerosol Medicine and Pulmonary Drug Delivery, Ahead of Print.
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - March 7, 2019 Category: Respiratory Medicine Authors: Heino Stass Johannes Nagelschmitz Dominik Kappeler Knut Sommerer Astrid Patzlaff Boris Weimann Source Type: research

A prospective randomized comparative study of targeted versus empirical prophylactic antibiotics in the prevention of infective complications following transrectal ultrasound-guided prostate biopsy
Conclusion: TA was associated with a decreased risk of infection in TRPB.
Source: Annals of African Medicine - August 13, 2019 Category: African Health Authors: Alaba Fredrich Doherty Stephen Odunayo Ikuerowo Emmanuel Ajibola Jeje Nasiru Akanmu Ibrahim Olumuyiwa Louis Ojongbede Wasiu Bamidele Mutiu Olufunmilade Akinfolarin Omisanjo Abimbola Ayodeji Abolarinwa Source Type: research

Fournier & #39;s gangrene: Presentation and predictors of mortality in Zaria, Nigeria
Conclusion: Fournier's gangrene is a disease of the older men with a higher mortality rate when the FGSI is >9 or anemia requiring blood transfusion is present.
Source: Annals of African Medicine - June 30, 2021 Category: African Health Authors: Nasir Oyelowo Muhammed Ahmed Ahmad Tijani Lawal Abdullahi Sudi Awaisu Mudi Musliu Adetola Tolani Lovely Fidelis Ahmad Bello Husseini Yusuf Maitama Source Type: research

Correlation between Drug Resistance of < em > Klebsiella Pneumonia < /em > and Antimicrobial Drug Usage
Conclusion. The use of antimicrobial drugs is correlated with the resistance rate of Klebsiella pneumoniae. To reduce bacterial drug resistance, the rational use of antimicrobial drugs requires joint control through multiple departments to improve the clinical use of antimicrobial drugs and improve in-hospital control.PMID:35586696 | PMC:PMC9110160 | DOI:10.1155/2022/2691134
Source: Evidence-based Complementary and Alternative Medicine - May 19, 2022 Category: Complementary Medicine Authors: Anyun Liu Jun Dai Ru Shen Feng Zhong Xuehe Sheng Houbao Huang Source Type: research

Pharmacological Management of Inflammatory Bowel Disease: a Century of Expert Opinions in Cecil Textbook of Medicine
Conclusions: The pharmacological management of IBD has been the focus of intense research and development in the past 60 years. The pillars of drug treatment have been 5-aminosalicylates and corticosteroids. Recent pharmacological innovations (immunomodulators and biologicals) constitute an encouraging paradigm shift in the treatment of UC and Crohn disease.
Source: American Journal of Therapeutics - September 1, 2022 Category: Drugs & Pharmacology Tags: Original Investigation Source Type: research