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Drug: Insulin
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Total 13136 results found since Jan 2013.
Practice of complementary and alternative medicine use in North Indian children with type 1 diabetes: an exploratory study
ConclusionCAM, mostly herbal, is frequently used among children with T1DM in North India and has detrimental effects on glycemic control. This information should be used during diabetes education to avoid medical emergencies related to sub-optimal insulin dosing.
Source: Diabetology International - September 22, 2023 Category: Endocrinology Source Type: research
South Africa: Aspen's Covid Vaccine Facility in Gqeberha Switches to Making Insulin for Africa
[Daily Maverick] Aspen South Africa will soon deliver millions of vials of human insulin to patients in Africa at a low cost after reaching an agreement with Novo Nordisk.
Source: AllAfrica News: Health and Medicine - September 21, 2023 Category: African Health Tags: Coronavirus Health and Medicine South Africa Southern Africa Source Type: news
The role of autophagy in the treatment of type II diabetes and its complications: a review
Type II diabetes mellitus (T2DM) is a chronic metabolic disease characterized by prolonged hyperglycemia and insulin resistance (IR). Its incidence is increasing annually, posing a significant threat to human life and health. Consequently, there is an urgent requirement to discover effective drugs and investigate the pathogenesis of T2DM. Autophagy plays a crucial role in maintaining normal islet structure. However, in a state of high glucose, autophagy is inhibited, resulting in impaired islet function, insulin resistance, and complications. Studies have shown that modulating autophagy through activation or inhibition can...
Source: Frontiers in Endocrinology - September 21, 2023 Category: Endocrinology Source Type: research
South Africa: Government Welcomes Novo Nordisk Announcement to Produce Insulin in SA
[SAnews.gov.za] The South African government welcomes the announcement by the global pharmaceutical company, Novo Nordisk, that it will produce insulin in South Africa.
Source: AllAfrica News: Health and Medicine - September 20, 2023 Category: African Health Tags: Health and Medicine South Africa Southern Africa Source Type: news
Africa: WHO Director-General's Opening Remarks At the UN General Assembly Side-Event - Empowering Lives: Bridging the Gap for Insulin Access in Africa - 19 September 2023
[WHO] Your Excellency Minister Nicolai Wammen,
Source: AllAfrica News: Health and Medicine - September 20, 2023 Category: African Health Tags: Africa External Relations Health and Medicine International Organizations and Africa Source Type: news
In vitro oxygen imaging of acellular and cell-loaded beta cell replacement devices
This article aims to establish the protocols and demonstrate a few examples of in vitro oxygen imaging of BAP devices using EPROI. All pO2 measurements were performed using a recently introduced 720 MHz/25 mT preclinical oxygen imager instrument, JIVA-25™. We began by performing pO2 calibration of the biomaterials used in BAPs at 25 mT magnetic field since no such data exist. We compared the EPROI pO2 measurement with a single-point probe for a few selected materials. We also performed trityl OX071 toxicity studies with fibroblasts, as well as insulin-producing cells (beta TC6, MIN6, and human islet cells). Finally, we p...
Source: Cancer Control - September 20, 2023 Category: Cancer & Oncology Authors: Mrignayani Kotecha Longhai Wang Safa Hameed Navin Viswakarma Minglin Ma Cherie Stabler Corinne A Hoesli Boris Epel Source Type: research
How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you…
Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China.
I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1
We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004.
Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news
Himalayan Mushroom Increases Sexual Stamina
In this study, the men received a dose of 250 mg.11
Look for wild-harvested cordyceps from Tibet
When choosing a supplement, always check the source. Some Cordyceps supplements come from harvested sources that are 50 times weaker than natural, wild sources.
As a supplement, I recommend wild Cordyceps from Tibet. Take 2 to 5 grams twice daily for best results.
You can also brew a cup of Cordyceps tea. I add peppermint to enhance the flavor. Here’s a simple recipe I use:
Boil 2 cups of filtered water in a small saucepan.
Add one gram of dried cordyceps to water. Boil vigorously for one minute.
Turn down the heat and simme...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Source Type: news
The Effect of Garlic (Allium Sativum) on Polycystic Ovary Syndrome Related Hormones and Glycemic Parameters: A Randomized, Double ‑Blinded Clinical Trial
Conclusions: Present study indicates that garlic supplementation could be beneficial for FPG and insulin resistance improvement. However, garlic supplementation does not show remarkable efficacy on androgens. Further studies are warranted to confirm the results.
Source: International Journal of Preventive Medicine - September 19, 2023 Category: International Medicine & Public Health Source Type: research
Monoamines' role in islet cell function and type 2 diabetes risk
Trends Mol Med. 2023 Sep 16:S1471-4914(23)00194-6. doi: 10.1016/j.molmed.2023.08.009. Online ahead of print.ABSTRACTThe two monoamines serotonin and melatonin have recently been highlighted as potent regulators of islet hormone secretion and overall glucose homeostasis in the body. In fact, dysregulated signaling of both amines are implicated in β-cell dysfunction and development of type 2 diabetes mellitus (T2DM). Serotonin is a key player in β-cell physiology and plays a role in expansion of β-cell mass. Melatonin regulates circadian rhythm and nutrient metabolism and reduces insulin release in human and rodent islets...
Source: Trends in Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Fiona Louise Roberts Luis Rodrigo Cataldo Malin Fex Source Type: research
Identification of quality markers for < em > Cyanotis arachnoidea < /em > and analysis of its physiological mechanism based on chemical pattern recognition, network pharmacology, and experimental validation
In this study, ultra-high-performance liquid chromatography (UHPLC) fingerprint combined with chemical pattern recognition were performed, and four differential components were screened out as quality markers, including 20-Hydroxyecdysone, 3-O-acetyl-20-hydroxyecdysone, Ajugasterone C, and 2-O-acetyl-20-hydroxyecdysone. Network pharmacology analysis revealed 107 therapeutic target genes of Cyanotis arachnoidea in DM treatment, and the key targets were Akt1, TNF, IL-6, MAPK3, and JUN. The hypoglycemic mode of action of Cyanotis arachnoidea may be mediated by tumor necrosis factor (TNF) signaling, cancer, insulin resistance,...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Jingnan Hu Yu Feng Baolin Li Fengxia Wang Qi Qian Wei Tian Liying Niu Xinguo Wang Source Type: research
Monoamines' role in islet cell function and type 2 diabetes risk
Trends Mol Med. 2023 Sep 16:S1471-4914(23)00194-6. doi: 10.1016/j.molmed.2023.08.009. Online ahead of print.ABSTRACTThe two monoamines serotonin and melatonin have recently been highlighted as potent regulators of islet hormone secretion and overall glucose homeostasis in the body. In fact, dysregulated signaling of both amines are implicated in β-cell dysfunction and development of type 2 diabetes mellitus (T2DM). Serotonin is a key player in β-cell physiology and plays a role in expansion of β-cell mass. Melatonin regulates circadian rhythm and nutrient metabolism and reduces insulin release in human and rodent islets...
Source: Trends in Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Fiona Louise Roberts Luis Rodrigo Cataldo Malin Fex Source Type: research
Comprehensive Search for GPCR Compounds which Can Enhance MafA and/or PDX-1 Expression Levels Using a Small Molecule Compound Library
In conclusion, fulvestrant and dexmedetomidine hydrochloride increased MafA, PDX-1, or insulin expression levels in MIN6 cells and islets from nondiabetic mice and obese type 2 diabetic db/db mice. To the best of our knowledge, this is the first report showing some molecule which can enhance MafA and/or PDX-1 expression levels. Therefore, although further extensive study is necessary, we think that the information in this study could be, at least in part, useful at some point such as in the development of new antidiabetes medicine based on the molecular mechanism of β-cell glucose toxicity in the future.PMID:37720599 | PM...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Hideaki Kaneto Atsushi Obata Masashi Shimoda Tomohiko Kimura Yoshiyuki Obata Tomoko Ikeda Saeko Moriuchi Shuhei Nakanishi Tomoatsu Mune Kohei Kaku Source Type: research
The Association between Circulating Adipocytokine Omentin Levels and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis
CONCLUSION: Additional well-designed studies with more sample sizes are essential to clarify the potential role of Omentin as a risk marker of NAFLD.PMID:37711002 | DOI:10.2174/1566524023666230913105910
Source: Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Rozita Khodashahi Mohsen Aliakbarian Gordon A Ferns Mohammad-Hassan Arjmand Source Type: research
