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Total 4434 results found since Jan 2013.
Defining an Opioid Sparing Treatment Pathway for Chronic Abdominal Pain of Somatic and Visceral Origin: A Case Series.
We present a treatment algorithm for chronic abdominal pain using a combination of interventional therapy using transversus abdominis plane (TAP) blocks along with post injection medical management for treatment of somatic and visceral pain. This is a case series of 4 patients presenting with diverse causes of chronic abdominal pain were treated with the treatment algorithm defined below. Patients received either bilateral or unilateral TAP blocks based on pain location using a combination of 0.25% bupivicaine 10ml, 40mg triamcinolone, and clonidine 50 mcg by a single physician upon admission to our acute care hospital. Fo...
Source: Journal of Pain and Palliative Care Pharmacotherapy - October 25, 2020 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Patient-Controlled Intravenous Analgesia for Advanced Cancer Patients with Pain: A Retrospective Series Study.
Conclusion: PCIA provided timely, safe, and satisfactory analgesia for advanced cancer patients with pain and may be useful for titration of opioids, management of severe breakthrough pain, and conversion to oral analgesia. There was no significant difference of analgesic effect and side effect among the hydromorphone, sufentanil, and oxycodone.
PMID: 29849846 [PubMed - in process]
Source: Pain Research and Management - June 1, 2018 Category: Anesthesiology Authors: Peng Z, Zhang Y, Guo J, Guo X, Feng Z Tags: Pain Res Manag Source Type: research
Perceptions of Community-Dwelling Patients and Their Physicians on OxyContin ® Discontinuation and the Impact on Chronic Pain Management.
Perceptions of Community-Dwelling Patients and Their Physicians on OxyContin® Discontinuation and the Impact on Chronic Pain Management.
Pain Res Manag. 2017;2017:5402915
Authors: Chang F, Ibrahim S
Abstract
OxyContin, formerly one of the most commonly prescribed medications for chronic pain in Canada, was discontinued, delisted from the Ontario Drug Formulary, and replaced by a tamper-resistant formulation in 2012. The impact of discontinuing OxyContin on patients formerly prescribed it to treat chronic pain was unreported. Patients with chronic pain aged 45 years and over (n = 13) were recruited fr...
Source: Pain Physician - March 3, 2017 Category: Anesthesiology Authors: Chang F, Ibrahim S Tags: Pain Res Manag Source Type: research
Pain Management of Malignant Psoas Syndrome Under Epidural Analgesia During Palliative Radiotherapy.
Authors: Ota T, Makihara M, Tsukuda H, Kajikawa R, Inamori M, Miyatake N, Tanaka N, Tokunaga M, Hasegawa Y, Tada T, Fukuoka M
Abstract
Malignant psoas syndrome is a rare malignant condition presenting as lumbosacral plexopathy and painful fixed flexion of the hip. Metastasis to the psoas muscle is observed, which damages the nerve bundles in the lumbosacral plexuses. The syndrome presents as refractory lower back pain with several other neurological symptoms. The pain is difficult to control because it is a mixture of nociceptive and neuropathic pain, which indicates that treatment requires a versatile approach. Th...
Source: Journal of Pain and Palliative Care Pharmacotherapy - April 6, 2017 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain.
Abstract
Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radiotherapy-induced side effects such as radiation esophagitis, enteritis, and mucositis. Pain control is reported to be inadequate during the whole course of radiotherapy (before, during, and after radiotherapy), and quality of life is seriously affected. Hence, radiotherapy is suggested to be ...
Source: Pain Research and Management - February 25, 2020 Category: Anesthesiology Authors: Wang Y, Xing L Tags: Pain Res Manag Source Type: research
A Comprehensive Review of Over the Counter Treatment for Chronic Low Back Pain.
Abstract
PURPOSE OF THE REVIEW: Chronic low back pain (CLBP) is a major contributor to societal disease burden and years lived with disability. Nonspecific low back pain (LBP) is attributed to physical and psychosocial factors, including lifestyle factors, obesity, and depression. Mechanical low back pain occurs related to repeated trauma to or overuse of the spine, intervertebral disks, and surrounding tissues. This causes disc herniation, vertebral compression fractures, lumbar spondylosis, spondylolisthesis, and lumbosacral muscle strain.
RECENT FINDINGS: A systematic review of relevant literature was cond...
Source: Pain Physician - November 4, 2020 Category: Anesthesiology Authors: Peck J, Urits I, Peoples S, Foster L, Malla A, Berger AA, Cornett EM, Kassem H, Herman J, Kaye AD, Viswanath O Tags: Pain Ther Source Type: research
Controlled-release oxycodone and naloxone in the treatment of chronic low back pain: A placebo-controlled, randomized study.
CONCLUSIONS: <⁄span> In patients complying with treatment as per protocol, CR oxycodone⁄CR naloxone was effective for the management of chronic low back pain of moderate or severe intensity.
PMID: 23662289 [PubMed - in process]
Source: Pain Research and Management - March 1, 2013 Category: Anesthesiology Authors: Cloutier C, Taliano J, O'Mahony W, Csanadi M, Cohen G, Sutton I, Sinclair D, Awde M, Henein S, Robinson L, Eisenhoffer J, Piraino PS, Harsanyi Z, Michalko KJ Tags: Pain Res Manag Source Type: research
Chronic opioid pain management for chronic kidney disease.
Authors: Nagar VR, Birthi P
Abstract
Questions from patients about pain conditions, pain treatment, and responses from authors are presented to help educate patients and make them effective self-advocates. The topics addressed in this issue are renal or kidney failure and chronic pain management with opioids, morphine, and oxycodone effect in the body over a period of time. This includes process of absorption, distribution, localization in tissues, biotransformation and excretion in chronic kidney disease, expected side effects and recommendations.
PMID: 25558925 [PubMed - in process]
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Pharmacokinetics of oxycodone after intravenous and subcutaneous administration in Japanese patients with cancer pain.
Authors: Kokubun H, Yoshimoto T, Hojo M, Fukumura K, Matoba M
Abstract
ABSTRACT In Japan, Oxycodone hydrochloride injection formulation has been approved in 2012. However, its pharmacokinetics has been poorly studied. The aim of this study is to evaluate the pharmacokinetics of oxycodone after intravenous and subcutaneous administration of oxycodone hydrochloride injection in Japanese patients with cancer pain. Noncompartmental analysis and population pharmacokinetic analysis were performed. We conducted a multicenter open-label study of oxycodone hydrochloride administered as constant infusion with the dose titrat...
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Comparative Analgesic Efficacy of Oxycodone/Acetaminophen vs Codeine/Acetaminophen for Short ‐Term Pain Management Following ED Discharge
ConclusionOur hypothesis that oxycodone/acetaminophen provides analgesia superior to codeine/acetaminophen was rejected. Although pain within each group was reduced by more than half, the between‐group difference was not significant. Pending independent validation, these unexpected findings suggest that codeine/acetaminophen, a Schedule III agent, may be a clinically reasonable outpatient opioid alternative to oxycodone/acetaminophen, a more tightly restricted Schedule II agent thought to be more prone to misuse.
Source: Pain Medicine - July 13, 2015 Category: Anesthesiology Authors: Andrew K. Chang, Polly E. Bijur, Jason B. Lupow, E. John Gallagher Tags: ACUTE & PERIOPERATIVE PAIN SECTION Source Type: research
Fentanyl tolerance in the treatment of cancer pain: a case of successful opioid switching from fentanyl to oxycodone at a reduced equivalent dose.
Authors: Sutou I, Nakatani T, Hashimoto T, Saito Y
Abstract
Opioids are not generally deemed to have an analgesic ceiling effect on cancer pain. However, there have been occasional reports of tolerance to opioid development induced by multiple doses of fentanyl. The authors report a case of suspected tolerance to the analgesic effect of opioid, in which an increasing dose of fentanyl failed to relieve the patient's cancer pain symptoms, but opioid switching to oxycodone injections enabled a dose reduction to below the equivalent dose conversion ratio. The patient was a 60-year-old man diagnosed with pancreatic body...
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Laxative Use in Inpatients on Oxycodone/Naloxone Prolonged Release and Oxycodone Prolonged Release for Cancer and Non-cancer Pain.
CONCLUSION: This retrospective study of hospital inpatients with cancer and non-cancer pain found that laxative use was not reduced in those on combined oxycodone/naloxone compared to oxycodone alone, suggesting that despite the interpretations of the clinical trials in the phase IV setting, the addition of naloxone had no effect on reducing laxative use.
PMID: 30735070 [PubMed - as supplied by publisher]
Source: Journal of Pain and Palliative Care Pharmacotherapy - February 10, 2019 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Roger Chou ’s Undisclosed Conflicts of Interest: How the CDC’s 2016 Guideline for Prescribing Opioids for Chronic Pain Lost Its Clinical and Professional Integrity
by Chad D. Kollas MD, Terri A. Lewis PhD, Beverly Schechtman and Carrie Judy“I ' m present. Uh … I do have a conflict. I receive funding to conduct reviews on opioids, and I ' ll be recusing myself after the um, director ' s, uh, um, um, uh … update.”- Dr. Roger Chou, Center for Disease Control and Prevention (CDC) National Center for Injury Prevention and Control (NCIPC) Board of Scientific Counselors (BSC) Meeting Friday, July 16, 2021.IntroductionFor those familiar with the controversial relationship between the anti-opioid advocacy group, Physicians for Responsible Opioid Prescribing (PROP, recently renamed, He...
Source: Pallimed: A Hospice and Palliative Medicine Blog - September 17, 2021 Category: Palliative Care Tags: CDC judy kollas lewis opioid pain schechtman Source Type: blogs
Roger Chou s Undisclosed Conflicts of Interest: How the CDCs 2016 Guideline for Prescribing Opioids for Chronic Pain Lost Its Clinical and Professional Integrity
by Chad D. Kollas MD, Terri A. Lewis PhD, Beverly Schechtman and Carrie JudyI ' m present. Uh I do have a conflict. I receive funding to conduct reviews on opioids, and I ' ll be recusing myself after the um, director ' s, uh, um, um, uh update.- Dr. Roger Chou, Center for Disease Control and Prevention (CDC) National Center for Injury Prevention and Control (NCIPC) Board of Scientific Counselors (BSC) Meeting Friday, July 16, 2021.IntroductionFor those familiar with the controversial relationship between the anti-opioid advocacy group, Physicians for Responsible Opioid Prescribing (PROP, recently renamed, Health Pro...
Source: Pallimed: A Hospice and Palliative Medicine Blog - September 17, 2021 Category: Palliative Care Tags: CDC judy kollas lewis opioid pain schechtman Source Type: blogs
Beyond the Basics: How Should We Manage Acute Pain in Hospitalized Patients with OUD?
Case
A 23-year-old male with opioid use disorder (OUD) with intravenous use is hospitalized with a fever and several weeks of back pain. He is diagnosed with methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis of the cervical spine. He desires medication treatment for OUD (MOUD) but is afraid of inadequate pain management while hospitalized. During previous admissions, untreated pain and withdrawal led to in-hospital substance use.
Brief overview of issue
The opioid epidemic is increasing hospitalizations and inpatient mortality related to OUD.1 Patients with injection use can experience painful, lif...
Source: The Hospitalist - November 1, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Clinical Guidelines Key Clinical Questions Pain Source Type: research
