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Total 18422 results found since Jan 2013.

Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate‐photodynamic therapy
ConclusionsMAL‐PDT is safe and effective in patients with Gorlin syndrome. Utilization of these recommendations may improve efficacy and clearance rates in this population.
Source: Journal of the European Academy of Dermatology and Venereology - April 13, 2013 Category: Dermatology Authors: N. Basset‐Seguin, R. Bissonnette, C. Girard, M. Haedersdal, J.T. Lear, C. Paul, S. Piaserico Tags: Original Article Source Type: research

How are physicians treating patients with Gorlin syndrome in the real world? Data from the RegiSONIC disease registry
We describe clinical characteristics, first-line treatment patterns, and preliminary outcomes in pts with Gorlin syndrome from RegiSONIC (NCT01604252), a prospective, multicenter, observational study.
Source: Journal of the American Academy of Dermatology - May 31, 2017 Category: Dermatology Source Type: research

Correction for Sear et al., Human settlement of East Polynesia earlier, incremental, and coincident with prolonged South Pacific drought Correction
ENVIRONMENTAL SCIENCES Correction for “Human settlement of East Polynesia earlier, incremental, and coincident with prolonged South Pacific drought,” by David A. Sear, Melinda S. Allen, Jonathan D. Hassall, Ashley E. Maloney, Peter G. Langdon, Alex E. Morrison, Andrew C. G. Henderson, Helen Mackay, Ian W. Croudace, Charlotte Clarke, Julian P....
Source: Proceedings of the National Academy of Sciences - June 15, 2020 Category: Science Tags: Corrections Source Type: research

Gorlin-Goltz syndrome: Case report and the importance of familiar tracking
Fundamentals: Gorlin-Goltz syndrome is a rare dominant autosomal genodermatosis, with high penetrance and variable expressivity.
Source: Journal of the American Academy of Dermatology - May 31, 2017 Category: Dermatology Source Type: research

26991 A decade to diagnose, a lifetime to treat: The time burden associated with basal cell carcinoma in patients with Gorlin syndrome
Gorlin syndrome (GS) is a rare autosomal dominant disorder that can affect every organ system. Patients have lifelong risk of multiple basal cell carcinomas (BCCs) appearing as early as the first decade. Physical and emotional burdens of current treatments, such as surgical excision, Mohs surgery, topicals, and oral agents, over a person ’s lifetime, are tremendous and include time lost from work, school, social, and athletic activities. The burden of time required for treatments is one of issues examined in a 58-question survey administered by the GS advocacy communities (US and UK), which had 246 respondents.
Source: Journal of the American Academy of Dermatology - August 8, 2021 Category: Dermatology Authors: Julie Breneiser, Alix Alderman, Srikanth Pendyala, S øren Holm Source Type: research

Differences of Search Engine Digital Footprints Between Podiatrists and Foot and Ankle Orthopaedic Surgeons: A Need to Join the Digital Era
DISCUSSION: Foot and ankle-related Internet search terms results are overwhelmingly composed of podiatry-oriented sites. Per provider, regional differences are demonstrated, with FAOS having more sites in urban areas only. FAOS scope-of-practice terms such as "ankle replacement" still retain greater engagement by FAOSs. Search engine optimization and saturation strategies should be considered.LEVEL OF EVIDENCE: Level 3 (observational study).PMID:36067461 | DOI:10.5435/JAAOS-D-22-00189
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 6, 2022 Category: Orthopaedics Authors: Benjamin J Chiang Zeeshan Malik Logan Laubach Prem Minchu Alex Gu Marc D Chodos Source Type: research

Levy flights do not always optimize random search Biophysics and Computational Biology
It is generally believed that random search processes based on scale-free, Lévy stable jump length distributions (Lévy flights) optimize the search for sparse targets. Here we show that this popular search advantage is less universal than commonly assumed. We study the efficiency of a minimalist search model based on Lévy...
Source: Proceedings of the National Academy of Sciences - February 25, 2014 Category: Science Authors: Palyulin, V. V., Chechkin, A. V., Metzler, R. Tags: Physical Sciences Source Type: research

The role of memory for visual search in scenes
Many daily activities involve looking for something. The ease with which these searches are performed often allows one to forget that searching represents complex interactions between visual attention and memory. Although a clear understanding exists of how search efficiency will be influenced by visual features of targets and their surrounding distractors or by the number of items in the display, the role of memory in search is less well understood. Contextual cueing studies have shown that implicit memory for repeated item configurations can facilitate search in artificial displays. When searching more naturalistic envir...
Source: Annals of the New York Academy of Sciences - February 12, 2015 Category: Science Authors: Melissa Le‐Hoa Võ, Jeremy M. Wolfe Tags: Original Article Source Type: research

43.5 depression-related internet search volume as a correlate of future child and adolescent suicides: a cross-correlational study of monthly google search volume and suicide rate of young individuals in the united states
This study examined whether the trends in MGSVs of any suicide-related search term preceded the variations in MSRs of young people in the United States.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2020 Category: Psychiatry Authors: Joo-Young Lee Source Type: research

Battling the Matthew Effect: Can Search Results be Fair?
Search engines are mediators between producers and consumers of information, and the order in which an engine presents its results affects both stakeholder groups in significant ways (e.g., economic livelihood). Top-ranked items provide their producers with much more exposure to the consumer than do lower-ranked items. If a search engine repeatedly returns comparably relevant items in the same order, the rich (more exposed) items will keep getting richer while lower-ranked items will get less and less relative exposure. The Text REtrieval Conference (TREC, trec.nist.gov) project at NIST contained a Fair Ranking track from...
Source: Videocast - All Events - August 30, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Attention does not search uniformly Neuroscience
Difficult search tasks are known to involve attentional resources, but the spatiotemporal behavior of attention remains unknown. Are multiple search targets processed in sequence or in parallel? We developed an innovative methodology to solve this notoriously difficult problem. Observers performed a difficult search task during which two probes were flashed...
Source: Proceedings of the National Academy of Sciences - December 8, 2015 Category: Science Authors: Dugue, L., McLelland, D., Laȷous, M., VanRullen, R. Tags: Biological Sciences Source Type: research

Data Flash: RIP PubMed Health
This is not exactly a data post, but, the loss of a trusted source for clinical effectiveness research will have its effects on the dataverse.  PubMed Health is being discontinued as of this coming Wednesday.  As any of my colleagues can tell you, I’m taking the loss of PubMed Health hard– I loved showing it to people at various conferences, and using it myself– I found it a wonderful mid-point between MedlinePlus.gov and PubMed.gov, and it also had some great methodology resources and a glossary.  All of its content will be findable in other ways though! In thinking about how to proceed in future with...
Source: Dragonfly - October 28, 2018 Category: Databases & Libraries Authors: Ann Glusker Tags: Data Science Public Health clinical effectiveness PubMed Health PubMed.gov search skills Source Type: news

Intrinsic motivation and attentional capture from gamelike features in a visual search task.
Abstract In psychology research studies, the goals of the experimenter and the goals of the participants often do not align. Researchers are interested in having participants who take the experimental task seriously, whereas participants are interested in earning their incentive (e.g., money or course credit) as quickly as possible. Creating experimental methods that are pleasant for participants and that reward them for effortful and accurate data generation, while not compromising the scientific integrity of the experiment, would benefit both experimenters and participants alike. Here, we explored a gamelike sys...
Source: Behavior Research Methods - July 9, 2013 Category: Psychiatry & Psychology Authors: Miranda AT, Palmer EM Tags: Behav Res Methods Source Type: research

Multimodal neuroimaging evidence linking memory and attention systems during visual search cued by context
Visual search can be facilitated by the learning of spatial configurations that predict the location of a target among distractors. Neuropsychological and functional magnetic resonance imaging (fMRI) evidence implicates the medial temporal lobe (MTL) memory system in this contextual cueing effect, and electroencephalography (EEG) studies have identified the involvement of visual cortical regions related to attention. This work investigated two questions: (1) how memory and attention systems are related in contextual cueing; and (2) how these systems are involved in both short‐ and long‐term contextual learning. In one ...
Source: Annals of the New York Academy of Sciences - January 13, 2015 Category: Science Authors: Ryan W. Kasper, Scott T. Grafton, Miguel P. Eckstein, Barry Giesbrecht Tags: Original Article Source Type: research