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Development of Prediction Model Using Machine-Learning Algorithms for Nonsteroidal Anti-inflammatory Drug-Induced Gastric Ulcer in Osteoarthritis Patients: Retrospective Cohort Study of a Nationwide South Korean Cohort
CONCLUSIONS: We obtained a prediction model for NSAID-induced gastric ulcers using the GBM method. Since personal prescription period and the severity of comorbidities were considered numerically, individual patients' risk could be well reflected. The prediction model showed high performance and interpretability, so it is meaningful to both clinicians and NSAID users.PMID:37529187 | PMC:PMC10375806 | DOI:10.4055/cios22240
Source: Clinics in Orthopedic Surgery - August 2, 2023 Category: Orthopaedics Authors: Jaehan Jeong Hyein Han Du Hyun Ro Hyuk-Soo Han Sungho Won Source Type: research

Content validation of a daily patient-reported outcome measure for assessing symptoms in patients with Small Intestinal Bacterial Overgrowth
ConclusionsThis study provides evidence supporting the content validity of the new PRO. Comprehensive patient input ensures that the SSM is a well-defined measure of SIBO, ready for psychometric validation studies.
Source: Quality of Life Research - August 1, 2023 Category: Health Management Source Type: research

Prediction of knee joint pain in Tai Chi practitioners: a cross-sectional machine learning approach
Conclusion CatBoost-based machine learning classifier accurately predicts knee pain symptoms after practicing Tai Chi. This study provides an essential reference for practicing Tai Chi scientifically to avoid knee pain.
Source: BMJ Open - August 1, 2023 Category: General Medicine Authors: Xing, H., Su, X., Liu, Y., Chen, Y., Ju, Y., Kang, Z., Sun, W., Yao, F., Yao, L., Gong, L. Tags: Open access, Sports and exercise medicine Source Type: research

Acupoint Catgut Embedding Diminishes Fibromyalgia Pain through TRPV1 in the Mouse Brain
CONCLUSIONS: These novel findings suggest that chronic FM pain can be modulated by ACE or TRPV1 gene deletion. The analgesic effect of ACE through the TRPV1 pathway may reflect its potential as a therapeutic target for FM treatment.PMID:37519181 | DOI:10.31083/j.jin2204097
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Po-Chih Lai Chia-Ming Yen I-Han Hsiao Yung-Hsiang Chen Yi-Wen Lin Source Type: research