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P38. Automatic segmentation of dura for quantitative analysis of lumbar stenosis: a deep learning study with 518 CT myelograms
The diagnosis of lumbar spinal stenosis (LSS) could be challenging, as radicular pain was not often presented for culprit level localization. Accurate segmentation and quantitative analysis of lumbar dura on radiographic images is key to the differential diagnosis of LSS.
Source: The Spine Journal - August 22, 2023 Category: Orthopaedics Authors: Guoxin Fan, Xiang Liao Source Type: research
Exploring Psychedelic Microdosing
Recently I’ve taken an interest in microdosing, specifically with magic mushrooms. I began learning about it a few months ago and then learned even more at the Psychedelic Science conference in June. I’ve also had some recent conversations with people I know who’ve been microdosing, all of them reporting positive long-term effects. Most use mushrooms for microdosing, although one prefers microdosing with LSD.
The point of microdosing is to take a very small amount of a psychedelic substance in order to access some neurological gains without any obvious psychedelic effects or impairments. Those gains can be both sh...
Source: Steve Pavlina's Personal Development Blog - August 21, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Emotions Health Lifestyle Productivity Source Type: blogs
Nearly 900,000 Learn to Prevent Tooth Decay Through America ' s ToothFairy HERO Education Program
The nationwide program is possible with support from Align Technology.Staff from Sonrisas Dental Health use the ToothFairy 101 ® Community Education Kit to teach youngsters at their school in San Mateo, CA about the importance of healthy dental hygiene habits. Sonrisas Dental Health receives free educational resources from America’s ToothFairy to help them serve more children in marginalized communities each year.(Charlotte, NC, August 15, 2023) – More than 69 million people live in dental care health professional shortage areas, where on average only 31.75% of the population have their dental needs m...
Source: Dental Technology Blog - August 21, 2023 Category: Dentistry Source Type: news
What Are Underlying Risk Factors for Liver Abscesses?
This study specific excluded patients with ALA or candidemia.
LA treatment is usually antibiotics and less invasive surgical techniques such as aspiration or percutaneous catheter drainage, but other treatment including resection is sometimes needed Overall mortality from LA has decreased from 15-40% to as low as 0.8% in the pediatric populations as noted above.
Learning Point
LA can occur solely because of exposure to infectious organisms but is also commonly associated with hepatobiliary pathology as well.
In Northern India study, the “[m]ajority of …children had no predisposing factors for development of LA ...
Source: PediatricEducation.org - August 21, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Animal Welfare Noncompliance: Data and Process
Brent C. Morse, DVM, DACLAM, Director, OLAW Division of Compliance Oversight Office of Extramural Research, NIH
As part of proper stewardship of taxpayer funds, we at NIH are obligated, both legally and ethically, to ensure the welfare and reduce risks for those involved in our supported research activities. This obligation includes research animals. Their humane care and use is something we take very seriously. We appreciate that Congress, the research community, interest groups, and other members of the public look towards us to observe this commitment. Today we are taking some time to touch upon our policies to protec...
Source: NIH Extramural Nexus - August 17, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Animal Welfare Grants policy Source Type: funding
Is robotic ventral mesh rectopexy for pelvic floor disorders better than laparoscopic approach at the beginning of the experience? A retrospective single-center study
ConclusionDespite longer operative time at the beginning of the learning curve, robotic ventral mesh rectopexy was associated with similar or better perioperative results than laparoscopic ventral mesh rectopexy.
Source: International Journal of Colorectal Disease - August 17, 2023 Category: Gastroenterology Source Type: research
Study Courses Supercharge Anatomy & Physiology Success | TAPP 141
Get ready for a mind-bending 😲 rendezvous with Kevin Patton inEpisode 141, where he continues to spill the beans on histop-secret recipe for student triumph. 🏆 Brace yourself for this next adventure on his whirlwind tour of revolutionizing A&P 1 education, as we dissect the art of identifyingstudent pain points, personalizing preparation, and serving up the kind ofmentorship they ' ve been yearning for!0:00:00 | Introduction0:00:45 | One of Two Success Courses0:09:48 | Setting Up the Supplement Course0:18:44 | Structure of Class Sessions0:40:17 | Grading0:42:45 | Does an A&P Sup...
Source: The A and P Professor - August 17, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs
Is robotic ventral mesh rectopexy for pelvic floor disorders better than laparoscopic approach at the beginning of the experience? A retrospective single-center study
ConclusionDespite longer operative time at the beginning of the learning curve, robotic ventral mesh rectopexy was associated with similar or better perioperative results than laparoscopic ventral mesh rectopexy.
Source: International Journal of Colorectal Disease - August 17, 2023 Category: Gastroenterology Source Type: research
Presentation of new onset type 1 diabetes with diabetic ketoacidosis and hyperosmolar hyperglycaemia after a single dose of nivolumab and ipilimumab
Endocrinol Diabetes Metab Case Rep. 2023 Aug 16;2023(3):22-0389. doi: 10.1530/EDM-22-0389. Print 2023 Aug 1.ABSTRACTSUMMARY: A Caucasian man in his 60s with recent diagnosis of metastatic renal cell carcinoma presented to the emergency department with a 5-day history of severe polyuria, polydipsia and fatigue and 1-day history of confusion, abdominal pain, nausea and vomiting. Investigations revealed an overlap of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic state (HHS). He had received the first dose of immunotherapy with nivolumab and ipilimumab 3 weeks prior to this attendance. New-onset type 1 diabetes (...
Source: Cancer Control - August 16, 2023 Category: Cancer & Oncology Authors: Dimitra Stathi Sufyan Hussain Danielle Crawley Janaka Karalliedde Source Type: research
Persistent pain management in an oncology population through pain neuroscience education, a multimodal program: PaiNEd randomized clinical trial protocol
DISCUSSION: The proposed study may help BC patients with persistent pain improve their pain experience, quality of life and provide for more adaptive pain-coping strategies. This protocol could propose an action guide to implement different integral approaches for the treatment of sequelae. This treatment option could be offered to this patient profile and it could be easily implemented in the healthcare systems due to its low costs.TRIAL REGISTRATION: ClinicalTrials.gov, NCT04877860. (February18, 2022).PMID:37582097 | PMC:PMC10426993 | DOI:10.1371/journal.pone.0290096
Source: Cancer Control - August 15, 2023 Category: Cancer & Oncology Authors: Miguel Ángel Fernández-Gualda Patrocinio Ariza-Vega Mario Lozano-Lozano Irene Cantarero-Villanueva Lydia Mart ín-Martín Eduardo Castro-Mart ín Manuel Arroyo-Morales Isabel Tovar-Mart ín Maria Lopez-Garzon Paula Postigo-Martin Ángela González-Santo Source Type: research
Content validation of a daily patient-reported outcome measure for assessing symptoms in patients with Small Intestinal Bacterial Overgrowth
ConclusionsThis study provides evidence supporting the content validity of the new PRO. Comprehensive patient input ensures that the SSM is a well-defined measure of SIBO, ready for psychometric validation studies.
Source: Quality of Life Research - August 14, 2023 Category: Health Management Source Type: research
Can ’ t You Just Do a Hydrogen Breath Test?
Discussion
Lactose is a sugar that is commonly found in dairy products. It is digested by the enzyme lactase mainly found on the brush border of the small bowel. Lactase production varies by age and genetics, with infants and young children having a generally higher amount than older children and adults, presumably as they have a more dairy-based diet. There is decreased production starting around 2-3 years of age (i.e. lactase non-persistence). Some people continue to produce lactase at the same levels as infants (i.e. lactase-persistence. “Lactase persistence (lactose tolerance) is seen predominantly in individuals...
Source: PediatricEducation.org - August 14, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Prediction of opioid-related outcomes in a medicaid surgical population: Evidence to guide postoperative opiate therapy and monitoring
ConclusionsA machine learning models to predict risk of OR-AE following surgery performed well in external validation. This work could be used to assist pain management following surgery for Medicaid beneficiaries and supports a precision medicine approach to opioid prescribing.
Source: PLoS Computational Biology - August 14, 2023 Category: Biology Authors: Oualid El Hajouji Source Type: research
Novel object recognition test as an alternative approach to assessing the pharmacological profile of sigma-1 receptor ligands
CONCLUSIONS: The nonlinear dose-response effect of PRE-084 in this assay does not justify its use for routine assessment of the functional activity of σ1R ligands.PMID:37572216 | DOI:10.1007/s43440-023-00516-x
Source: Pharmacological Reports - August 12, 2023 Category: Drugs & Pharmacology Authors: Katarzyna Szczepa ńska Andrzej J Bojarski Piotr Popik Natalia Malikowska-Racia Source Type: research
