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Source: Experimental and Therapeutic Medicine
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Total 17866 results found since Jan 2013.
< em > Ginkgo biloba < /em > extract protects human neuroblastoma SH-SY5Y cells against oxidative glutamate toxicity by activating redoxosome-p66Shc
Exp Ther Med. 2021 Sep;22(3):951. doi: 10.3892/etm.2021.10383. Epub 2021 Jul 5.ABSTRACTGinkgo biloba extract (GBE), a traditional Chinese herbal medicine component, is widely used to alleviate symptoms of neurodegenerative diseases. It has been confirmed that GBE exerts its pharmacological effect mainly due to its antioxidant activity; however, the molecular mechanism responsible for this effect remains unclear. The aim of the present study was to investigate the detailed mechanism of GBE, the main component of Gingko biloba dropping medicine, against oxidative glutamate toxicity in human neuroblastoma SH-SY5Y cells. The S...
Source: Experimental and Therapeutic Medicine - August 2, 2021 Category: General Medicine Authors: Ke Wang Jing Ni Xue Zhu Ling Zhu Yue Li Fanfan Zhou Source Type: research
Immunomodulatory effects of < em > Radix isatidis < /em > polysaccharides < em > in vitro < /em > and < em > in vivo < /em >
Exp Ther Med. 2021 Dec;22(6):1405. doi: 10.3892/etm.2021.10841. Epub 2021 Oct 4.ABSTRACTRadix isatidis (R. isatidis) is a commonly used traditional Chinese herbal medicine, which has been used for thousands of years in China and is believed to have the pharmacological properties of heat-clearing and detoxification. Heat-clearing and detoxification are theories of traditional Chinese medicine meaning that R. isatidis could treat febrile disease by clearing heat and reducing swelling. Polysaccharides isolated from R. isatidis by water extraction and alcohol precipitation have exhibited numerous biological activities, includi...
Source: Experimental and Therapeutic Medicine - October 22, 2021 Category: General Medicine Authors: Wei Tao Ting Fu Zhuo-Jing He Han-Peng Zhou Yan Hong Source Type: research
Effects of noni on cellular viability and osteogenic differentiation of gingiva-derived stem cells demonstrated by RNA sequencing and quantitative PCR
Exp Ther Med. 2022 Jan;23(1):32. doi: 10.3892/etm.2021.10954. Epub 2021 Nov 8.ABSTRACTNoni fruit (Morinda citrifolia) has been widely used in traditional medicine across tropical and subtropical regions, and is now being paid more attention in Western medicine. The present study aimed to investigate the effects of noni extract on the change in the cellular morphology, maintenance of cellular viability and enhancement of osteogenic differentiation of stem cells. Stem cells obtained from gingiva were cultured where noni extracts existed at concentrations ranging from 10-200 ng/ml. Evaluations of cell morphology and cellular ...
Source: Experimental and Therapeutic Medicine - November 26, 2021 Category: General Medicine Authors: Young-Min Song Hyun-Jin Lee Sae-Kyung Min Yoon-Hee Park Jae-Kwen Oh Ji-Youn Kim Jun-Beom Park Source Type: research
Life-threatening anemia due to uterine fibroids: A case series
Exp Ther Med. 2022 Sep 12;24(5):669. doi: 10.3892/etm.2022.11605. eCollection 2022 Nov.ABSTRACTUterine fibroids are associated with heavy menstrual bleeding, abdominal discomfort, subfertility and a reduced quality of life. The present study reported a case series of life-threatening anemia with hemoglobin levels <2.0 g/dl caused by uterine fibroids and genital bleeding. Case 1 was of a 34-year-old woman who was transported to the emergency department of the Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University because of a decline in consciousness level. She had been experiencing excessive and p...
Source: Experimental and Therapeutic Medicine - October 14, 2022 Category: General Medicine Authors: Michiko Kawano Mamiko Okamoto Mitsutake Yano Yasushi Kawano Source Type: research
