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Source: Jornal Brasileiro de Nefrologia
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Total 2173 results found since Jan 2013.
Chronic Hypertension: so much to learn.
Authors: Rodrigues CI
PMID: 27438967 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - July 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Increasing violent deaths and organ transplantation in Brazil: is there a parallel?
Authors: Oliveira JG, Oliveira MR, Vieira LJ, Silva GB
Abstract
Mortality from violent causes has significantly increased in Brazil, as well as the number of deceased-donor organ transplantation. Although the increase in the number of transplants correlates with higher organ availability, through the increase in potential donors, this is not the unique aspect to be considered. The effective and articulated action of transplantation network seems to be decisive to this outcome. Resumo A mortalidade por causas violentas tem aumentado de modo significativo no Brasil, bem como o número de transplantes de órgãos com ...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Outcome of renal transplantation from a donor with polycystic kidney disease.
This report of two cases of transplants performed from a donor with polycystic kidneys showed promising results, and the receptors evolved with good renal function, serum creatinine measurements within the normal range and with adequate glomerular filtration rate, evaluated over a period of four years post transplant. This fact confirms that the option of using donors with polycystic kidneys is safe and gives good results. Resumo Diante da longa fila de espera por um transplante renal, a utilização de doadores com critério expandido, a exemplo de rins policÃsticos, torna-se uma opção que visa aumentar a oferta de rin...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Acute tubulointerstitial nephritis with severe renal impairment associated with multisystem IgG4-related disease.
We describe the clinical presentation and evolution of a patient with acute tubulointerstitial nephritis, severe kidney failure and systemic manifestations such as lymphadenomegaly and chronic pancreatitis. The diagnosis was confirmed by the clinical picture and kidney and lymph node histopathology, in which immunohistochemistry of the lymphoid tissue showed policlonality and increased expression of IgG4, with a IgG4/total IgG ratio > 80%. The patient was treated with prednisone at a dose of 60 mg/day, followed by mycophenolate mofetil, and showed clinical and renal function improvement at 6 months of follow-up. The hig...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Rare case of nephrotic syndrome: Schimke syndrome.
The objective of this study was to report a case of Schimke syndrome, diagnostic investigation and management of the case. Resumo A sÃndrome Schimke corresponde à displasia imuno-óssea, associada à doença renal progressiva secundária à sÃndrome nefrótica córtico-resistente, podendo haver outras anormalidades como hipotireoidismo e aplasia de medula óssea. Trata-se de uma patologia genética rara, com poucos relatos na literatura. O acometimento renal mais frequente é uma sÃndrome nefrótica por glomeruloesclerose segmentar e focal e falência renal progressiva. O objetivo deste estudo foi relatar um caso de sÃ...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Hypertriglyceridemia: Is there a role for prophylactic apheresis? A case report.
We report a case of a 64 year-old woman with hypertrophic cardiomyopathy and metabolic syndrome with triglyceride level of 3260 mg/dL. Plasma exchange was performed with simultaneous medical treatment to achieve a rapid and effective lowering of triglycerides in order to prevent clinical complications. After three plasmapheresis sessions a marked reduction in triglyceride and total cholesterol levels was observed. Several cases have shown the importance of plasmapheresis in the treatment of acute pancreatitis. We intend to demonstrate the applicability of this technique as primary prophylaxis in the presence of extremely h...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Transient hyperphosphatemia: a benign laboratory disorder in a boy with Gitelman syndrome.
We present a three year old boy with genetically confirmed Gitelman syndrome where THI was detected accidentally during periodic check-up. S-ALP peaked to 41.8 µkat/L, there were neither laboratory or clinical signs of liver or bone disease; the S-ALP dropped to normal value of 4 µkat/L 60 days later. Therefore, the patient fulfilled the criteria for THI. There were no further increases in S-ALP. Resumo A hiperfosfatasemia transitória benigna da infância (HTBI) é caracterizada por elevação transitória da atividade da fosfatase alcalina sérica (S-ALP), predominantemente em sua isoforma óssea ou hepática, em crian...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Hepcidin: an important iron metabolism regulator in chronic kidney disease.
Authors: Antunes SA, Canziani ME
Abstract
Anemia is a common complication and its impact on morbimortality in patients with chronic kidney disease (CKD) is well known. The discovery of hepcidin and its functions has contributed to a better understanding of iron metabolism disorders in CKD anemia. Hepcidin is a peptide mainly produced by hepatocytes and, through a connection with ferroportin, it regulates iron absorption in the duodenum and its release of stock cells. High hepcidin concentrations described in patients with CKD, especially in more advanced stages are attributed to decreased renal excretion and increa...
Source: Jornal Brasileiro de Nefrologia - October 14, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Purple urine bag syndrome: case report for Streptoccocus agalactiae and literature review.
We report a case of purple urine bag syndrome, associated to Streptococcus agalactiae urinary tract infection, progressing to septic shock and death. We present a review of the literature on the subject and take the opportunity to attend readers about increasing incidence with population aging and its potential bad outcome.
PMID: 28001191 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
An update on pathology of IgA nephropathy.
Authors: Soares MF
Abstract
IgA Nephropathy (IgAN) is the commonest of the glomerular diseases in the world. Its progression rate of 30-40% of the cases em 20-30 years makes IgAN an important healthcare issue in Nephrology. Diagnosis of IgAN depends on biopsy findings, particularly at immunofluorescence microscopy. The frequence of IgAN diagnosis is variable in different populations and depends on screening and biopsy indication policies. IgAN pathogenesis is considered multifactorial; its primordial defect is the production of galactosis-deficient IgA molecules. This review paper discusses the most uptodate aspect...
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Acute myeloid leukemia after kidney transplantation: a case report and literature review.
We report the case of a 33-year-old man who presented with fever, pancytopenia and acute worsening of his renal allograft function 9 years after a living unrelated kidney transplant. After initial negative infectious work-up, a kidney biopsy revealed C4d-positive antibody-mediated rejection in combination with scattered atypical inflammatory cells. A subsequent bone marrow biopsy confirmed AML. He underwent successful induction chemotherapy with daunorubucin and cytarabine and ultimately achieved a complete remission. However, he developed a Page kidney with worsening renal function and abdominal pain three weeks after bio...
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Author's response.
Authors: Peres LA
PMID: 28001188 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Treatment of idiopathic light chain deposition disease: complete remission with bortezomib and dexamethasone.
Authors: Souto Filho JT, Monteiro JM, Andrade IB
Abstract
Light chain deposition disease (LCDD) is a rare clinical entity characterized by the deposition of light chain immunoglobulins in different tissues and primarily affects the kidneys, followed by the liver and heart. This disease often manifests as nephrotic syndrome with marked proteinuria and rapid deterioration of renal function. More than 50% of cases are secondary to multiple myeloma or other lymphoproliferative diseases, with a well-established treatment aimed at controlling the underlying disease. In rare cases, there is no detection of an associated h...
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Hypercalcemia and renal function impairment associated with vitamin D toxicity: case report.
We report a case of a 70 year old diabetic male with chronic renal disease (blood creatinine of 1.6 mg/dL) who progressed suddenly to acute kidney injury (blood creatinine of 5.7 mg/dL) associated with hypercalcemia and high blood levels of vitamin D. Vitamin D and calcitriol were discontinued and hypercalcemia was managed by hydration followed by furosemide. Thereafter, disodium pamidronate was administered and the patient did not undergo on dialysis. It took approximately 14 months to normalize 25-OHD levels and blood creatinine returned to basal levels only after 24 months. The indicated labeling dosage was 2000 IU, but...
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Serum uric acid and its association with hypertension, early nephropathy and chronic kidney disease in type 2 diabetic patients.
CONCLUSION: Even high normal SUA level, was associated with the risk of hypertension, early nephropathy and decline of eGFR. Moreover SUA level may identify the onset of hypertension, early nephropathy and progression of CKD in T2DM.
PMID: 28001185 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
