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Effect of cholecalciferol supplementation on urine podocyte-associated messenger RNAs in patients with chronic kidney disease.
CONCLUSION: Six months of cholecalciferol supplementation had no effect on urine podocyte-associated mRNA profile of patients with advanced CKD. The protective effect of vitamin D or its analogues on the glomerular podocyte should be investigated in early stages of CKD with a longer treatment period. PMID: 27438972 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - July 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Patient in chronic hemodialysis with right atrial mass: thrombus, fungal endocarditis or atrial myxoma?
We present the case report of a 19-year-old patient with chronic kidney disease due to chronic glomerulonephritis, in hemodialysis (HD) by central catheter, with the incidental finding of a mass of 28x16 mm in right atrium (RA). The diagnosis of thrombus, infective endocarditis or myxoma were considered. Given the context of immunosuppression and difficult access vascular therapeutic practice has proved complex. Although Doppler echocardiography suggested thrombus in RA, nuclear magnetic resonance imaging (MRI) indicated for the diagnosis of myxoma in RA. In both conditions, the proposed surgical approach was limited by in...
Source: Jornal Brasileiro de Nefrologia - December 22, 2016 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Budd-Chiari syndrome secondary to catheter-associated inferior vena cava thrombosis.
CONCLUSION: Assessment of catheter dialysis tip location with radiological image seems to be a prudent measure after each procedure even if the tunneled dialysis catheter has been introduced with fluoroscopy image. PMID: 28355402 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - March 30, 2017 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Brazilian Chronic Dialysis Survey 2016.
CONCLUSION: The absolute number and the prevalence and incidence rates of patients on dialysis continue to rise steadily; the gross mortality rate remained stable. Regional inequities are evident in these rates. PMID: 29044335 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - October 19, 2017 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Renal artery pseudoaneurysm.
This report is a case of a patient submitted a right percutaneous renal biopsy and that, after the procedure started with macroscopic haematuria, urinary tenesmus and hypogastric pain. The diagnosis of pseudoaneurysm was given after one week of evolution when the patient was hospitalized because gross haematuria, tachycardia, hypotension and hypochondrium pain. In the angiotomography revealed a focal dilation of the accessory right renal inferior polar artery, dilation of renal pelvis and all the ureteral course with presence hyperdenso material (clots) inside the middle third of the ureter. The treatment for the majority ...
Source: Jornal Brasileiro de Nefrologia - January 11, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Peritoneal dialysis as the first dialysis treatment option initially unplanned.
Authors: Mendes ML, Alves CA, Bucuvic EM, Dias DB, Ponce D Abstract Most patients with stage 5 CKD start RRT of unplanned manner. Unplanned dialysis, also known as urgent start, may be defined as hemodialysis (HD) started without permanent vascular access, i.e., using a central venous catheter (CVC), or as peritoneal dialysis (PD) started within seven days after implantation of the catheter, without family training. Although few studies have evaluated the PD as an immediate treatment option for patients starting urgent RRT, theirs results suggest that it is a feasible and safe alternative, with infectious complicat...
Source: Jornal Brasileiro de Nefrologia - January 11, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Complement System and C4d expression in cases of Membranous nephropathy.
CONCLUSION: C4d was associated with increased interstitial fibrosis, but not with clinical markers of poor prognosis. Through the deposition of C4d and C1q we demonstrated that all complement pathways may be involved in MN, highlighting the lectin pathway. The presence of C4d has been associated with severe tubulointerstitial lesions, but not with clinical markers, or can be taken as a universal marker of all cases of MN. PMID: 29319762 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - January 11, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Prior intake of Brazil nuts attenuates renal injury induced by ischemia and reperfusion.
CONCLUSION: Low intake of BN prior to IR-induced kidney injury improves renal function by inhibition of macrophage infiltration and oxidative stress. PMID: 29738035 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - May 10, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Renal oncocytoma in a kidney transplant patient: the imaging features on contrast-enhanced ultrasonography (CEUS): a case report.
We present a case report of an asymptomatic renal oncocytoma in a kidney transplant recipient presenting persistent hematuria. The features of computed tomography and contrast-enhanced ultrasound (CEUS) are presented. This was the first time we used CEUS in a transplant kidney recipient presenting a renal mass, allowing the real-time visualization of contrast-enhancement patterns during all vascular phases for the differential diagnosis of renal tumors. Although the pattern of intense vascularization could mislead to an early judgment as a malignant lesion, it could help to exclude other renal lesions without inducing neph...
Source: Jornal Brasileiro de Nefrologia - May 10, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Prior intake of Brazil nuts attenuates renal injury induced by ischemia and reperfusion.
CONCLUSION: Low intake of BN prior to IR-induced kidney injury improves renal function by inhibition of macrophage infiltration and oxidative stress. PMID: 29796584 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - May 30, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Renal oncocytoma in a kidney transplant patient: the imaging features on contrast-enhanced ultrasonography (CEUS): a case report.
We present a case report of an asymptomatic renal oncocytoma in a kidney transplant recipient presenting persistent hematuria. The features of computed tomography and contrast-enhanced ultrasound (CEUS) are presented. This was the first time we used CEUS in a transplant kidney recipient presenting a renal mass, allowing the real-time visualization of contrast-enhancement patterns during all vascular phases for the differential diagnosis of renal tumors. Although the pattern of intense vascularization could mislead to an early judgment as a malignant lesion, it could help to exclude other renal lesions without inducing neph...
Source: Jornal Brasileiro de Nefrologia - May 30, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Polymorphism related to cardiovascular risk in hemodialysis subjects: a systematic review.
Authors: Balbino KP, Hermsdorff HHM, Bressan J Abstract Cardiovascular disease (CVD) is one of the leading causes of mortality in hemodialysis (HD) subjects. In addition to the traditional risk factors that are common in these individuals, genetic factors are also involved, with emphasis on single nucleotide polymorphs (SNPs). In this context, the present study aims to systematically review the studies that investigated the polymorphisms associated with cardiovascular risk in this population. In general, the SNPs present in HD individuals are those of genes related to inflammation, oxidative stress and vascular cal...
Source: Jornal Brasileiro de Nefrologia - June 29, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Inflammation and kidney injury attenuated by prior intake of Brazil nuts in the process of ischemia and reperfusion.
CONCLUSION: In experimental IR, the damage can be minimized with a prior low-dose intake of BN, improving inflammation, injury, and cell death. PMID: 30118536 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - August 19, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Salvage of thrombosed arteriovenous fistulae of patients on hemodialysis: report on the experience of a Brazilian center.
CONCLUSION: The majority of thrombosed accesses can be successfully treated, maintaining its long-term patency. The need of repeated intervention is frequent. PMID: 30207374 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - September 14, 2018 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis.
We report a case of SRC in a patient with scleroderma-dermatomyositis overlap syndrome, which also showed clinical and histopathological data of TMA. On fundus examination, a severe acute hypertensive retinopathy was found. The kidney biopsy showed severe endothelial damage with widening of mucoid cells at the level of the intima, focal concentric proliferation on most small arterioles, and C3, C4d, and IgM deposits along the capillary walls. The genetic study of complement only showed the presence of membrane cofactor protein (MCP) risk haplotypes, without other genetic complement disorders. We understand that in a patien...
Source: Jornal Brasileiro de Nefrologia - February 27, 2019 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

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