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Infectious Disease: Endemics

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Total 16640 results found since Jan 2013.

Cardiovascular Involvement in Beh çet Disease: Clinical Implications
We present two male patients from the Mediterranean Basin with BD. The first was diagnosed early as a BD patient. The second was diagnosed at the time of cardiovascular (CV) involvement. We recommend that patients who are diagnosed, or even suspected of suffering from BD, especially in endemic areas along the Silk Route pathway, should be followed up routinely for CV involvement, even if rare, obscure, or with a bizarre presentation.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  Full text
Source: International Journal of Angiology - June 4, 2015 Category: Cardiology Authors: Yahalom, Malka Bloch, Lev Suleiman, Khaled Rosh, Bar Turgeman, Yoav Tags: Original Article Source Type: research

Cutaneous fistulization of the hydatid disease: A PRISMA-compliant systematic review
Conclusion: Cutaneous fistulization is a rare complication of HD. Complicated HD should be considered in the differential diagnosis of cases presenting with cutaneous fistulization, particularly in regions where HD is endemic.
Source: Medicine - September 1, 2016 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Risk factors for Gleason score upgrading following radical prostatectomy: a review of the current literature.
CONCLUSIONS: The various studies found that Gleason score upgrading remains highly prevalent, and that some association can be seen with greater percent positive cores, longer biopsy core lengths, smaller prostate glands, higher percent tumour volume per gland, PSA density and visible lesions on mp-MRI. PMID: 28008754 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - December 24, 2016 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Histopathological assessment of chronic Corynebacterium pseudotuberculosis infection in the reproductive tract and iliac lymph node of Katjang does
This study shows the time dependent effect ofC. pseudotuberculosis infection on lesion severity in the reproductive system of goats, which necessitates the need for prompt diagnosis in order to prevent infertility and abortion in goat herds.
Source: Comparative Clinical Pathology - December 31, 2016 Category: Pathology Source Type: research

Cutaneous larva migrans.
CONCLUSION: The pruritic serpiginous track is pathognomonic. Oral ivermectin is the treatment of choice. PMID: 28078983 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - January 14, 2017 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Research Articles Fingolimod treatment abrogates chikungunya virus-induced arthralgia
Chikungunya virus (CHIKV) is one of the many rheumatic arthropod-borne alphaviruses responsible for debilitating joint inflammation in humans. Despite the severity in many endemic regions, clinically approved intervention targeting the virus remains unavailable. CD4+ T cells have been shown to mediate CHIKV-induced joint inflammation in mice. We demonstrate here that transfer of splenic CD4+ T cells from virus-infected C57BL/6 mice into virus-infected T cell receptor–deficient (TCR–/–) mice recapitulated severe joint pathology including inflammation, vascular leakages, subcutaneous edema, and skeletal mus...
Source: Science Translational Medicine - January 31, 2017 Category: Biomedical Science Authors: Teo, T.-H., Chan, Y.-H., Lee, W. W. L., Lum, F.-M., Amrun, S. N., Her, Z., Rajarethinam, R., Merits, A., Rötzschke, O., Renia, L., Ng, L. F. P. Tags: Research Articles Source Type: research

The Child Sexual Abuse Conspiracy
BY DAVID INTROCASO (After this essay was submitted to THCB the Senate Judiciary Committee held a hearing on March 28th titled, “Protecting Young Athletes From Sexual Abuse.” USA Gymnastics refused to appear and provide testimony likely, in part, because USA Gymnastics’ President, Steve Penny, was forced to resign on March 16th. The issue was framed by Committee Chairman Chuck Grassley as a “heinous crime,” no health care or public health expert testified and the hearing and was reported in sports pages of the The New York Times and The Washington Post.) If you do not read the sports page you ...
Source: The Health Care Blog - March 31, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

Why highly effective drugs are not enough: the need for an affordable solution to eliminating HCV.
Authors: Hayes CN, Chayama K Abstract INTRODUCTION: Because of the rapid pace of development of new direct-acting antiviral (DAA) drugs, chronic hepatitis C virus (HCV) infection is now increasingly considered curable. However, the emphasis on DAA therapies disregards key issues related to cost, availability, and antiviral resistance. Areas covered: This perspective provides an overview of current HCV therapies and the development of DAAs, followed by a discussion of the limitations of DAA therapy. A literature search was used to select relevant studies, and a web search for relevant news articles and press release...
Source: Expert Review of Clinical Pharmacology - April 5, 2017 Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research

Atypical presentations of cutaneous leishmaniasis: a systematic review.
ATYPICAL PRESENTATIONS OF CUTANEOUS LEISHMANIASIS: A SYSTEMATIC REVIEW. Acta Trop. 2017 May 16;: Authors: Meireles CB, Maia LC, Soares GC, Teodoro IPP, do Socorro Vieira Gadelha M, da Silva CGL, de Lima MAP Abstract Cutaneous Leishmaniasis (CL) is endemic in 88 countries, showing relevant prevalences. The aim of this study was to perform a systematic review on atypical lesions of CL around the world, addressing clinico-epidemiological, immunological and therapeutic aspects. A search of the literature was conducted via electronic databases Scopus and PubMed for articles published between 2010 and 2015....
Source: Acta Tropica - May 16, 2017 Category: Infectious Diseases Authors: Meireles CB, Maia LC, Soares GC, Teodoro IPP, do Socorro Vieira Gadelha M, da Silva CGL, de Lima MAP Tags: Acta Trop Source Type: research

The Use of Mobile Apps and SMS Messaging as Physical and Mental Health Interventions: Systematic Review
Conclusions: The review shows the promising and emerging efficacy of using mobile apps and SMS text messaging as mHealth interventions.
Source: Journal of Medical Internet Research - August 24, 2017 Category: General Medicine Authors: Amy Leigh Rathbone Julie Prescott Source Type: research

Renal effects of Bunodosoma caissarum crude extract: Prostaglandin and endothelin involvement.
Abstract Sea anemones contain a variety of interesting biologically active compounds, including some potent toxins. PLA2 from Bunodosoma caissarum, a sea anemone endemic in the Brazilian southern coast, has shown renal alterations on isolated kidney. The aim of this study was to evaluate the renal and vascular effects of B. caissarum crude extract (BcE) on isolated perfused kidney and arteriolar mesenteric bed, as well the involvement of prostaglandins and endothelin. BcE did not show any effect on arteriolar mesenteric bed, but increased perfusion pressure, renal vascular resistance, urinary flow, glomerular fil...
Source: Toxicon - August 23, 2017 Category: Toxicology Authors: Martins RD, Jorge RJB, Alves RS, Silva Neto AGD, Barbosa PSF, Costa Martins AM, Toyama MH, Monteiro HSA Tags: Toxicon Source Type: research

Considerations of potential vectors and animal reservoirs in an emerging cutaneous leishmaniasis area in S ão Domingos ranch, Paraná State in Southearn Brazil.
Considerations of potential vectors and animal reservoirs in an emerging cutaneous leishmaniasis area in São Domingos ranch, Paraná State in Southearn Brazil. Rev Inst Med Trop Sao Paulo. 2017 Sep 04;59:e64 Authors: Membrive NA, Hisatugo F, Silveira TGV, Teixeira JJV, Reinhold-Castro KR, Teodoro U Abstract The aim of this study was to better understand the dynamics of Leishmania sand flies and reservoirs in São Domingos ranch, Arapongas municipality, Paraná State, an anthropic environment in an endemic area of cutaneous leishmaniasis (CL). Sand flies were collected in wild animal burrows, residenc...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 4, 2017 Category: Tropical Medicine Authors: Membrive NA, Hisatugo F, Silveira TGV, Teixeira JJV, Reinhold-Castro KR, Teodoro U Tags: Rev Inst Med Trop Sao Paulo Source Type: research

Prevalence of hepatitis D virus infection in sub-Saharan Africa: a systematic review and meta-analysis
Publication date: October 2017 Source:The Lancet Global Health, Volume 5, Issue 10 Author(s): Alexander J Stockdale, Mas Chaponda, Apostolos Beloukas, Richard Odame Phillips, Philippa C Matthews, Athanasios Papadimitropoulos, Simon King, Laura Bonnett, Anna Maria Geretti Background Hepatitis D virus (also known as hepatitis delta virus) can establish a persistent infection in people with chronic hepatitis B, leading to accelerated progression of liver disease. In sub-Saharan Africa, where HBsAg prevalence is higher than 8%, hepatitis D virus might represent an important additive cause of chronic liver disease. We aimed to...
Source: The Lancet Global Health - September 12, 2017 Category: International Medicine & Public Health Source Type: research

Larvivorous fish for preventing malaria transmission.
CONCLUSIONS: We do not know whether introducing larvivorous fish reduces malaria transmission or the density of adult anopheline mosquito populations.In research studies that examined the effects on immature anopheline stages of introducing fish to potential malaria vector larval habitats, high stocking levels of fish may reduce the density or presence of immature anopheline mosquitoes in the short term. We do not know whether this translates into impact on malaria transmission. Our interpretation of the current evidence is that countries should not invest in fish stocking as a stand alone or supplementary larval control m...
Source: Cochrane Database of Systematic Reviews - December 11, 2017 Category: General Medicine Authors: Walshe DP, Garner P, Adeel AA, Pyke GH, Burkot TR Tags: Cochrane Database Syst Rev Source Type: research

Hepatitis B virus infection in the Democratic Republic of Congo: a systematic review of prevalence studies (2000 –2016)
ConclusionThis review suggests that DRC is a country characterized by an intermediate level of HBV infection endemicity rate. It remains however an important public health problem and efforts should continue in prevention and in policy to control this viral disease.
Source: Journal of Public Health - January 19, 2018 Category: Health Management Source Type: research