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Infectious Disease: Endemics
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Total 16640 results found since Jan 2013.
Epidemiology of Crimean-Congo Hemorrhagic Fever (CCHF) in Africa-Underestimated for Decades
Am J Trop Med Hyg. 2021 Apr 26:tpmd201413. doi: 10.4269/ajtmh.20-1413. Online ahead of print.ABSTRACTCrimean-Congo hemorrhagic fever (CCHF) is endemic in Africa, but the epidemiology remains to be defined. Using a broad database search, we reviewed the literature to better define CCHF evidence in Africa. We used a One Health approach to define the impact of CCHF by reviewing case reports, human and animal serology, and records of CCHF virus (CCHFV) isolations (1956-mid-2020). In addition, published and unpublished collection data were used to estimate the geographic distribution of Hyalomma ticks and infection vectors. We ...
Source: The American Journal of Tropical Medicine and Hygiene - April 26, 2021 Category: Tropical Medicine Authors: Ahmet Irfan Temur Jens H Kuhn David B Pecor Dmitry A Apanaskevich Maryam Keshtkar-Jahromi Source Type: research
Chemotherapy Treatments for Burkitt Lymphoma: Systematic Review of Interventional Studies
CONCLUSION: Selecting chemotherapy protocols for BL should be grounded in its epidemiologic variants. Further studies with greater methodological quality are needed to strengthen the evidence.PMID:33947633 | DOI:10.1016/j.clml.2021.03.012
Source: Clinical Lymphoma and Myeloma - May 5, 2021 Category: Cancer & Oncology Authors: Ana M Della Rocca Let ícia P Leonart Vinicius L Ferreira Fernanda S Tonin Giovanna Steffenello-Durigon Joanita A G Del Moral Fernando Fernandez-Llimos Roberto Pontarolo Source Type: research
Effect of mass deworming with antihelminthics for soil-transmitted helminths during pregnancy
CONCLUSIONS: The evidence suggests that administration of a single dose of antihelminthics in the second trimester of pregnancy may reduce maternal anaemia and worm prevalence when used in settings with high prevalence of maternal helminthiasis. Further data is needed to establish the benefit of antihelminthic treatment on other maternal and pregnancy outcomes. Future research should focus on evaluating the effect of these antihelminthics among various subgroups in order to assess whether the effect varies. Future studies could also assess the effectiveness of co-interventions and health education along with antihelminthic...
Source: Cochrane Database of Systematic Reviews - May 17, 2021 Category: General Medicine Authors: Rehana A Salam Jai K Das Zulfiqar A Bhutta Source Type: research
Relationship of fluoride in drinking water with blood pressure and essential hypertension prevalence: a systematic review and meta-analysis
ConclusionThe risk of elevated blood pressure increases in the general population of fluoride endemic areas. However, more research is needed to make a firm conclusion about the adverse effects of excess fluoride intake on the cardiovascular system at the individual level.
Source: International Archives of Occupational and Environmental Health - May 20, 2021 Category: Occupational Health Source Type: research
Macrovipera lebetina obtusa Snake Venom as a Modulator of Antitumor Effect in S-180 Sarcoma Mouse Model
Mol Biol (Mosk). 2021 May-Jun;55(3):468-477. doi: 10.31857/S0026898421030071.ABSTRACTMacrovipera lebetina obtusa (MLO) is a venomous snake endemic to Middle East. Here we describe the therapeutic potential of the MLO snake venom. In S-180 sarcoma-bearing mouse model, we showed that the MLO snake venom inhibits tumour growth by 50%. In human dermal microvascular endothelial cells (HMVEC-D), treatment with the MLO snake venom lead to an increase of expression levels of the vascular endothelial growth factor (VEGF), while the level of the expression of caspase 8 did not change. In HMVEC-D cells MLO snake venom induces necropt...
Source: Molekuliarnaia Biologiia - June 7, 2021 Category: Molecular Biology Authors: N Ghazaryan N Movsisyan J C Macedo S Vaz N Ayvazyan L Pardo E Logarinho Source Type: research
