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Infectious Disease: Malaria
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Traditional Medicinal Uses, Phytoconstituents, Bioactivities, and Toxicities of < em > Erythrina abyssinica < /em > Lam. ex DC. (Fabaceae): A Systematic Review
CONCLUSION: Erythrina abyssinica is an important ethnomedicinal plant in Africa harboring useful pharmacologically active phytochemicals against various diseases with significant efficacies and minimal toxicity to mammalian cells. Therefore, this plant should be conserved and its potential to provide novel molecules against diseases be explored further. Clinical trials that evaluate the efficacy and safety of extracts and isolated compounds from E. abyssinica are recommended.PMID:33763144 | PMC:PMC7952165 | DOI:10.1155/2021/5513484
Source: Evidence-based Complementary and Alternative Medicine - March 25, 2021 Category: Complementary Medicine Authors: Samuel Baker Obakiro Ambrose Kiprop Elizabeth Kigondu Isaac K'Owino Mark Peter Odero Scolastica Manyim Timothy Omara Jane Namukobe Richard Oriko Owor Yahaya Gavamukulya Lydia Bunalema Source Type: research
A PLOS Medicine Collection on Plasmodium vivax--a neglected cause of malaria
(PLOS) Strenuous efforts to prevent in recent decades have brought great benefits, particularly against disease caused by Plasmodium falciparum in countries in Africa and the Americas. But malaria caused by its " stealthier and more resilient cousin " , P. vivax, now needs to be confronted with high priority, say Lorenz von Seidlein and Nicholas White of the Mahidol Oxford Tropical Medicine Research Unit in Bangkok, Thailand in a Perspective. The piece introduces a Collection on the prevention and treatment of P. vivax malaria in PLOS Medicine.
Source: EurekAlert! - Infectious and Emerging Diseases - April 23, 2021 Category: Infectious Diseases Source Type: news
Drug Shop Intervention to Enhance Knowledge, Attitude, and Practices of Patent Medicine Vendors for the Control of COVID-19 In Southeastern Nigeria
Am J Trop Med Hyg. 2021 Jun 3:tpmd201549. doi: 10.4269/ajtmh.20-1549. Online ahead of print.ABSTRACTDrug shops are the first point of care for most community members in low-resource countries. Because of symptomatic similarities with common illnesses such as malaria, probable coronavirus disease 2019 (COVID-19) cases may seek care at drug shops, where the knowledge and skills required to handle it may be lacking, thereby fostering community spread of the disease. This single-arm study provided an intervention to improve COVID-19-related knowledge, attitude, and practices of patent medicine vendors (PMVs) in 97 participatin...
Source: Am J Trop Med Hyg - June 20, 2021 Category: Infectious Diseases Authors: Uchechukwu Madukaku Chukwuocha Gregory Ndubeze Iwuoha Onyeka Francis Ashinze Princewill Ugochukwu Njoku Chidera Chisom Obasi Evelyn Ifezue Adey Ikechukwu Nosike Simplicius Dozie Source Type: research
Molecules, Vol. 26, Pages 6922: The Future of Carica papaya Leaf Extract as an Herbal Medicine Product
Pandu Hariyono
Carica papaya (papaya) leaf extract has been used for a long time in a traditional medicine to treat fever in some infectious diseases such as dengue, malaria, and chikungunya. The development of science and technology has subsequently made it possible to provide evidence that this plant is not only beneficial as an informal medication, but also that it has scientifically proven pharmacological and toxicological activities, which have led to its formal usage in professional health care systems. The development of formulations for use in nutraceuticals and cosmeceuticals has caused this product to be m...
Source: Molecules - November 17, 2021 Category: Chemistry Authors: Maywan Hariono Jeffry Julianus Ipang Djunarko Irwan Hidayat Lintang Adelya Friska Indayani Zerlinda Auw Gabriel Namba Pandu Hariyono Tags: Review Source Type: research
Common childhood illnesses: a cross-sectional study of commodity stocking patterns and management knowledge among patent and proprietary medicine vendors in Nigeria
ConclusionThe relative constant availability of medicines and commodities for managing childhood illnesses positions PPMVs as a preferred source of care for these illnesses. There is a need to complement steady stock availability with provision of quality services by exposing PPMVs to trainings on integrated community case management of childhood illnesses and implementation of robust supervision mechanism to monitor them.
Source: Archives of Public Health - March 22, 2022 Category: International Medicine & Public Health Source Type: research
Discovery and repurposing of artemisinin
AbstractMalaria is an ancient infectious disease that threatens millions of lives globally even today. The discovery of artemisinin, inspired by traditional Chinese medicine (TCM), has brought in a paradigm shift and been recognized as the “best hope for the treatment of malaria” by World Health Organization. With its high potency and low toxicity, the wide use of artemisinin effectively treats the otherwise drug-resistant parasites and helps many countries, including China, to eventually eradicate malaria. Here, we will first rev iew the initial discovery of artemisinin, an extraordinary journey that was in stark cont...
Source: Frontiers of Medicine - March 15, 2022 Category: General Medicine Source Type: research
A Strategic Partnership for Medicine Creation and Access to Medicine for Neglected Tropical Diseases
Yakugaku Zasshi. 2022;142(7):703-708. doi: 10.1248/yakushi.21-00210-4.ABSTRACTNeglected tropical diseases (NTDs) are communicable diseases that are uncommon in developed countries but epidemic in developing countries of the tropical and subtropical regions around the world. One of the important contributions expected of pharmaceutical companies is the development and provision of drugs effective against NTDs. Firstly, Eisai has distributed at price zero to endemic countries worldwide diethylcarbamazine (DEC) tablets for patients suffering with lymphatic filariasis (LF). Eisai's efforts toward improving global health have r...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 5, 2022 Category: Drugs & Pharmacology Authors: Katsura Hata Source Type: research
The Antiplasmodial Potential of Medicinal Plants Used in the Cameroonian Pharmacopoeia: An Updated Systematic Review and Meta-Analysis
Evid Based Complement Alternat Med. 2022 Oct 8;2022:4661753. doi: 10.1155/2022/4661753. eCollection 2022.ABSTRACTMalaria is a real public health problem. It is the leading cause of morbidity and mortality in the world. Research in herbal medicine has so far shown that the use of plants against malaria is not to be neglected. This review aims to highlight the antiplasmodial potential of Cameroonian plants. In order to achieve this objective, we conducted a bibliographic search in April 2022 using the PubMed search engine. This research included both the published and unpublished studies. A narrative approach was used to des...
Source: Evidence-based Complementary and Alternative Medicine - October 18, 2022 Category: Complementary Medicine Authors: Arnaud Gabin N Tepa Panthaleon Ambassa Lawrence S Ayong Prosper Cabral Biapa Nya Constant Anatole Pieme Source Type: research
Women in Acupuncture Research: Interviews with Leaders of the Field
Med Acupunct. 2022 Oct 1;34(5):285-293. doi: 10.1089/acu.2022.29217.int. Epub 2022 Oct 17.ABSTRACTWhen Tu Youyou was awarded the Nobel Prize for her discovery of artemisinin (qīnghāosù) extract to treat malaria, she became the first female scientist from the Peoples Republic of China to win the Nobel Prize, and her prize was the first awarded for a Traditional Chinese Medicine preparation. Inspired by Tu's accomplishment, this special issue in Medical Acupuncture aims to highlight the great contributions of women in the development of acupuncture and Chinese herbal medicine evidence base. We sought to interview some of ...
Source: Acupuncture in Medicine - October 31, 2022 Category: Complementary Medicine Authors: Lisa Taylor-Swanson Jennifer A Stone Source Type: research
Capacity Building in Pediatric Critical Care-Global Health Research and Education: The Blantyre Experience
Am J Trop Med Hyg. 2023 Jun 12:tpmd220445. doi: 10.4269/ajtmh.22-0445. Online ahead of print.ABSTRACTPediatric critical care medicine (PCCM), as it is practiced in high-income countries, is focused on specialized medical care for the most vulnerable pediatric patient populations. However, best practices for provision of that care globally are lacking. Thus, PCCM research and education programming can potentially fill significant knowledge gaps by facilitating the development of evidence-based clinical guidelines that reduce child mortality on a global scale. Malaria remains a leading cause of pediatric mortality worldwide....
Source: The American Journal of Tropical Medicine and Hygiene - June 12, 2023 Category: Tropical Medicine Authors: Madiha Q Raees Yamikani Chimalizeni Alice W Muiruri Liomba Paul Pensulo Montfort Benard Gushu Andrew Tebulo Albert Malenga Michael J Sikorski Adrian J Holloway Adnan T Bhutta Allan Doctor Kenneth E Remy Nicole F O'Brien Douglas G Postels Terrie E Taylor Source Type: research
