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Infectious Disease: Malaria

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Total 6951 results found since Jan 2013.

The Usefulness of Serum C-Reactive Protein and Total Bilirubin Levels for Distinguishing Between Dengue Fever and Malaria in Returned Travelers.
Abstract The clinical manifestations of dengue fever (DF) and malaria are similar. Specific diagnostic tests are not always available. A retrospective study to compare the laboratory results of malaria and DF was conducted at the National Center for Global Health and Medicine in Japan from January of 2005 to March of 2013. Febrile returned travelers from overseas diagnosed with malaria or DF were included; 86 malaria and 85 DF cases were identified. C-reactive protein (CRP) and total bilirubin (T-bil) had high area under the receiver operating characteristic curves (> 0.9). A cutoff value of CRP > 2.4 mg/dL ...
Source: The American Journal of Tropical Medicine and Hygiene - January 13, 2014 Category: Tropical Medicine Authors: Kutsuna S, Hayakawa K, Kato Y, Fujiya Y, Mawatari M, Takeshita N, Kanagawa S, Ohmagari N Tags: Am J Trop Med Hyg Source Type: research

Mefloquine restrictions, anti-malarial drug safety and the new Italian recommendations for malaria prophylaxis
The paper by Schneider et al. published in this issue of Travel Medicine and Infectious Disease (TMAID) investigates a relatively little explored potential toxicity of antimalarial prophylaxis, that is, eye toxicity. The authors conclude that the incidence of eye disorders is in fact slightly higher in users of any malaria prophylaxis regimen compared to non users of antimalarial prophylaxis, irrespective of the regimen used, and in particular not higher for mefloquine users than for subjects on other regimens. The authors rightly acknowledge the limitations of this observational study, on a relatively limited sample and ...
Source: Travel Medicine and Infectious Disease - December 12, 2013 Category: Infectious Diseases Authors: Zeno Bisoffi, Federico Gobbi, Guido Calleri Tags: Editorials Source Type: research

Saving Cameroonians from Ill Health
The Cameroon government says that the uncontrolled number of health clinics and training institutions are responsible for the death and worsening medical conditions of many here. Credit: Monde Kingsley Nfor/IPSBy Monde Kingsley NforYAOUNDE, Jan 23 2014 (IPS) The Cameroonian government has begun a crackdown on illegal medical facilities and plans to shut down more than 524 medical training centres and 600 private clinics operating unlawfully in this Central African nation.  “We are starting activities to bring order to the medical sector that has gone out of control. Most of [the illegal medical institutions] lack the tr...
Source: IPS Inter Press Service - Health - January 23, 2014 Category: Global & Universal Authors: Monde Kingsley Nfor Tags: Africa Bitter Pill: Obstacles to Affordable Medicine Development & Aid Editors' Choice Featured Headlines Health Human Rights Poverty & MDGs Projects Regional Categories TerraViva United Nations Cameroon Hospitals Medical Stand Source Type: news

Beyond Malaria — Causes of Fever in Outpatient Tanzanian Children
New England Journal of Medicine, Volume 370, Issue 9, Page 809-817, February 2014.
Source: New England Journal of Medicine - February 26, 2014 Category: Internal Medicine Tags: article Source Type: research

In vivo antimalarial activity of the crude leaf extract and solvent fractions of Croton macrostachyus Hocsht. (Euphorbiaceae) against Plasmodium berghei in mice
Conclusions: The results collectively indicate that the plant has a promising antiplasmodial activity against Plasmodium berghei, which upholds the earlier in vitro findings as well as its folkloric use. Thus, it could be considred as a potential source to develop new antimalarial agents.
Source: BMC Complementary and Alternative Medicine - March 1, 2014 Category: Complementary Medicine Authors: Laychiluh BantieSolomon AssefaTilahun TeklehaimanotEphrem Engidawork Source Type: research

Malarial liver parasites awaken in culture
Nature Medicine 20, 237 (2014). doi:10.1038/nm.3498 Authors: John W Barnwell & Mary R Galinski The cure and elimination of malaria caused by Plasmodium vivax is hindered by the threat of relapse infections from undetectable dormant forms of the parasite in the liver. In a new breakthrough, using a related parasite, Plasmodium cynomolgi, it has been shown that the small nongrowing forms of the parasite, termed hypnozoites, can be reactivated in primary simian hepatocytes that have been infected and maintained in culture for 40 days, providing a system to study this parasite form with the development of potential...
Source: Nature Medicine - March 4, 2014 Category: Journals (General) Authors: John W BarnwellMary R Galinski Tags: News and Views Source Type: research

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures
Nature Medicine 20, 307 (2014). doi:10.1038/nm.3461 Authors: Laurent Dembélé, Jean-François Franetich, Audrey Lorthiois, Audrey Gego, Anne-Marie Zeeman, Clemens H M Kocken, Roger Le Grand, Nathalie Dereuddre-Bosquet, Geert-Jan van Gemert, Robert Sauerwein, Jean-Christophe Vaillant, Laurent Hannoun, Matthew J Fuchter, Thierry T Diagana, Nicholas A Malmquist, Artur Scherf, Georges Snounou & Dominique Mazier
Source: Nature Medicine - February 9, 2014 Category: Journals (General) Authors: Laurent DembéléJean-François FranetichAudrey LorthioisAudrey GegoAnne-Marie ZeemanClemens H M KockenRoger Le GrandNathalie Dereuddre-BosquetGeert-Jan van GemertRobert SauerweinJean-Christophe VaillantLaurent HannounMatthew J FuchterThierry T DiaganaNic Tags: Technical Report Source Type: research

Combined efforts in immunology and vaccinology will lead to effective vaccines against HIV, tuberculosis and malaria
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - March 17, 2014 Category: Internal Medicine Authors: Francesca Chiodi, Stefan H. E. Kaufmann Tags: Introduction Source Type: research

Travel to Brazil: Analysis of Data From the Boston Area Travel Medicine Network (BATMN) and Relevance to Travelers Attending World Cup and Olympics
We describe travelers who were evaluated pre‐travel to Brazil from March 2008 through July 2010 in the Boston area. Of 599 Brazil travelers, 71%, 58%, and 50% received vaccines for yellow fever (YF), typhoid, and hepatitis A, respectively. Fewer received influenza and hepatitis B vaccines (14%, 11%). A total of 60% traveled during Brazil's peak influenza season, and one fourth visited during peak dengue transmission. The 2014 World Cup and 2016 Olympics include events throughout Brazil. Travelers should seek pre‐travel assessment including YF and malaria risk; travelers should be vaccinated against influenza, be up to ...
Source: Journal of Travel Medicine - March 1, 2014 Category: Infectious Diseases Authors: Eirini Iliaki, Lin H. Chen, Davidson H. Hamer, William B. Macleod, Emily S. Jentes, Elizabeth D. Barnett, Mary E. Wilson, Tags: BRIEF COMMUNICATION Source Type: research

Global Health: Even a Few Pills Can Put a Dent in the Malaria Rate
Doctors Without Borders finds that small, cheap doses of medicine helped children significantly during the rainy season in West Africa.
Source: NYT - April 28, 2014 Category: American Health Authors: By DONALD G. McNEIL Jr. Tags: Malaria Medicine and Health Source Type: news

Parasite Burden and Severity of Malaria in Tanzanian Children
New England Journal of Medicine, Volume 370, Issue 19, Page 1799-1808, May 2014.
Source: New England Journal of Medicine - May 7, 2014 Category: Internal Medicine Tags: article Source Type: research

Curious association between Plasmodium vivax malaria and nontraumatic acute subdural hematoma
Supradip GhoshIndian Journal of Critical Care Medicine 2014 18(5):335-336
Source: Indian Journal of Critical Care Medicine - May 14, 2014 Category: Intensive Care Authors: Supradip Ghosh Source Type: research

Cochrane review on use of rectal artesunate for severe malaria
(Liverpool School of Tropical Medicine) Researchers from the Cochrane Infectious Diseases Group, hosted at LSTM, conducted an independent review of the effects of pre-referral rectal artesunate for people with severe malaria, published in the Cochrane Library today. The review follows a large trial of rectal artesunate in 2009 which led the World Health Organization to recommend its use.
Source: EurekAlert! - Medicine and Health - May 30, 2014 Category: Global & Universal Source Type: news

The medically immunocompromised adult traveler and pre-travel counseling: Status quo 2014
Summary: International travel is increasing among a growing number of medically immunosuppressed patients regaining life-activity due to efficient drugs. Adequate pre-travel advice for this group of patients requires not only a travel-medicine expert but a relevant specialist as well, so that a personalized plan can be made concerning vaccinations and other prophylaxis. Inactivated vaccines can generally be prescribed during immunosuppressive therapy; the risk of inducing an exacerbation of the underlying disease is minimal and even though the post-vaccination antibody response will often be impaired, it will possibly bene...
Source: Travel Medicine and Infectious Disease - May 12, 2014 Category: Infectious Diseases Authors: Helena H. Askling, Virgil A.S.H. Dalm Tags: Reviews Source Type: research

Cochrane Review on primaquine to prevent malaria transmission
(Liverpool School of Tropical Medicine) Researchers from the Cochrane Infectious Diseases Group, hosted at LSTM, conducted an independent review of the effects of adding a single dose of primaquine to malaria treatment to prevent the transmission of the disease.
Source: EurekAlert! - Medicine and Health - July 3, 2014 Category: Global & Universal Source Type: news