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Infectious Disease: Osteomyelitis
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Total 1575 results found since Jan 2013.
Complex Case of Skull Base Osteomyelitis Secondary to Chronic Otitis Media
We present a case of a 58-year-old male with type II diabetes managed with metformin and insulin, who presented to the clinic with left chronic otitis media, persistent drainage, a stenotic meatus, and a prior history of 3 canal wall-down mastoidectomies and antibiotic therapy. A revision tympanoplasty with mastoidectomy was performed, and during the postoperative period, the patient had persistent pain and otorrhea, which were managed with opioids and several courses of antibiotic therapy. After symptoms persisted, imaging and culture ultimately led to the diagnosis of fungal skull base osteomyelitis, which was eventually...
Source: Ear, Nose and Throat Journal - July 29, 2023 Category: ENT & OMF Authors: Masa Petrovic Hannah G Landsberger Kevin A Peng Source Type: research
Diagnostic and therapeutic practices in adult chronic nonbacterial osteomyelitis (CNO)
CONCLUSIONS: Following from our survey data, adult CNO is a broad and insufficiently characterized disease spectrum, including extra-osseous features. MRI is the favoured imaging diagnostic, and management strategies vary significantly. Overall, pamidronate and anti-TNFα are regarded most successful. The results lay out current practices for adult CNO, which may serve as backbone for a future consensus clinical guideline.PMID:37480122 | PMC:PMC10362746 | DOI:10.1186/s13023-023-02831-1
Source: Pain Physician - July 21, 2023 Category: Anesthesiology Authors: A T Leerling G Clunie E Koutrouba O M Dekkers N M Appelman-Dijkstra E M Winter Source Type: research
Osteomyelitis caused by Streptococcus intermedius in immunocompetent adults — a case report and systematic literature review
AbstractHematogenous osteomyelitis caused byStreptococcus intermedius is rare, particularly in immunocompetent adults. The aim of this paper is to provide an overview of the clinical presentation, prognosis as well as treatment of this disease, with the focus on immunocompetent adults. Six medical literature libraries were searched to identify studies reporting onStreptococcus intermedius induced hematogenous osteomyelitis in immunocompetent adults. In addition, we presented a case of a 44-year-old man from our institution that is illustrative for this disease. Four case reports describing four patients were identified by ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - July 20, 2023 Category: Microbiology Source Type: research
Infection Management for the Hand Surgeon
Infections of the upper extremity can be challenging to diagnose and treat because of the complex anatomy and range of offending pathogens. Early recognition of infections that require an emergent surgical intervention, such as necrotizing fasciitis and septic joints, is imperative for good clinical outcomes. In addition, prompt diagnosis and intervention for deep closed space infections, such as deep abscesses or flexor tenosynovitis, is necessary to avoid chronic pain and dysfunction. Complicating factors such as underlying osteomyelitis, atypical pathogens, and immunocompromised states of patients should always be consi...
Source: Hand Clinics - July 14, 2023 Category: Orthopaedics Authors: Victor King, Nisha Crouser, Amy Speeckaert, Reena Bhatt Source Type: research
Chronic Recurrent Multifocal Osteomyelitis
Chronic recurrent multifocal osteomyelitis (CRMO) is an underrecognized autoinflammatory disease affecting the skeletal system. Its vague symptoms are often first attributed to growing pains, infection, or malignancy, which can lead to a delay in diagnosis for days to years. Untreated CRMO has the potential to cause debilitating skeletal deformities, arthritis, and chronic pain; hence early recognition and treatment are paramount. MRI is the gold standard for diagnosis. Treatment consists of various antiinflammatory medications and may also include bisphosphonates if vulnerable skeletal sites are involved. Even when treate...
Source: Medical Clinics of North America - July 11, 2023 Category: Primary Care Authors: Bridget A. Rafferty, Pooja Thakrar Source Type: research
Septic arthritis and transient synovitis of the hip
Radiologie (Heidelb). 2023 Jul 5. doi: 10.1007/s00117-023-01179-8. Online ahead of print.ABSTRACTCLINICAL/METHODICAL ISSUE: Differentiating between septic arthritis and transient synovitis can be challenging but is very important as a late diagnosis of septic arthritis can lead to sepsis and joint damage. For correct diagnosis and prediction of complications, the right combination of physical examination, laboratory and radiological studies is needed.STANDARD RADIOLOGICAL METHODS: Hip ultrasound is easy to learn and has a high sensitivity for joint effusion. Faster diagnosis and therapy are possible due to increasing use o...
Source: Nuklearmedizin - July 5, 2023 Category: Radiology Authors: S Appelhaus S O Schoenberg M Weis Source Type: research
Clinico-Radiological Evaluation for Longitudinal Assessment in Central Skull Base Osteomyelitis: Proposal of Novel Scoring System
This study aims to evaluate clinical, radiological and laboratory parameters for longitudinal assessment and prognostication in central skull base osteomyelitis (CSBO). Novel radiological score and cranial nerve assessment score (CNAS) have been proposed and analysed along with pain score (VAS), ESR, CRP, WBC count, and HbA1c for utility in disease-monitoring and predicting outcome in CSBO. CSBO cases managed in a tertiary care centre from January 2018 to November 2020, with a minimum follow-up of 6 months were included. The parameters were recorded at presentation, 3-month, 6-month postoperative follow-up, and at comple...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - July 4, 2023 Category: ENT & OMF Source Type: research
Incidence, Diagnosis and Risk Factors for Fracture-Related Infection (FRI): 3-Year Experience of Level I Trauma Centre
CONCLUSIONS The incidence of FRI at Level 1 trauma centre was 2.33% of operated fractures in 2019-2021, with pyogenic cocci being the most common infectious agents. The FRI usually developed within 6 months after osteosynthesis. The typical site for the FRI development was the lower limb region, the ongoing FRI was indicated by suggestive clinical criteria (redness, secretion, pain) and radiological criteria (delayed healing and a non-union). Overall, 42.19% of treated non-unions were later diagnosed as FRI. Key words: fracture-related infection, FRI, suggestive criteria, confirmatory criteria, FRI diagnosis, microbial, mi...
Source: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca - July 3, 2023 Category: Orthopaedics Authors: J Řimsa M Dole žalová Hrubá J Urban M Peml K Holub M Kloub Source Type: research
Feasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis
CONCLUSION: The CNO CDAS was developed and validated for disease monitoring and assessment of treatment effectiveness. CHOIR provided a comprehensive framework for future comparative effectiveness research.PMID:37399459 | DOI:10.3899/jrheum.2022-1323
Source: J Rheumatol - July 3, 2023 Category: Rheumatology Authors: Eveline Y Wu Melissa Oliver Joshua Scheck Sivia Lapidus Ummusen Kaya Akca Shima Yasin Sara M Stern Antonella Insalaco Manuela Pardeo Gabriele Simonini Edoardo Marrani Xing Wang Bin Huang Leonard K Kovalick Natalie Rosenwasser Gabriel Casselman Adriel Liau Source Type: research
Incidence, Diagnosis and Risk Factors for Fracture-Related Infection (FRI): 3-Year Experience of Level I Trauma Centre
CONCLUSIONS The incidence of FRI at Level 1 trauma centre was 2.33% of operated fractures in 2019-2021, with pyogenic cocci being the most common infectious agents. The FRI usually developed within 6 months after osteosynthesis. The typical site for the FRI development was the lower limb region, the ongoing FRI was indicated by suggestive clinical criteria (redness, secretion, pain) and radiological criteria (delayed healing and a non-union). Overall, 42.19% of treated non-unions were later diagnosed as FRI. Key words: fracture-related infection, FRI, suggestive criteria, confirmatory criteria, FRI diagnosis, microbial, mi...
Source: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca - July 3, 2023 Category: Orthopaedics Authors: J Řimsa M Dole žalová Hrubá J Urban M Peml K Holub M Kloub Source Type: research
Feasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis
CONCLUSION: The CNO CDAS was developed and validated for disease monitoring and assessment of treatment effectiveness. CHOIR provided a comprehensive framework for future comparative effectiveness research.PMID:37399459 | DOI:10.3899/jrheum.2022-1323
Source: Journal of Rheumatology - July 3, 2023 Category: Rheumatology Authors: Eveline Y Wu Melissa Oliver Joshua Scheck Sivia Lapidus Ummusen Kaya Akca Shima Yasin Sara M Stern Antonella Insalaco Manuela Pardeo Gabriele Simonini Edoardo Marrani Xing Wang Bin Huang Leonard K Kovalick Natalie Rosenwasser Gabriel Casselman Adriel Liau Source Type: research
