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Infectious Disease: Hepatitis

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Total 12583 results found since Jan 2013.

Formula-syndrome correlation study of three classical anti-jaundice formulas in inhibition of liver fibrosis induced by dimethylnitrosamine in rats.
Abstract OBJECTIVE: To explore the diagnostic value of 75 commonly used clinical laboratory markers for differentiation of traditional Chinese medicine syndromes such as liver and gallbladder damp-heat and liver depression and spleen deficiency in patients with chronic hepatitis B. METHODS: A total of 422 patients with chronic hepatitis B (CHB) were enrolled, including 300 patients with damp-heat in liver and gallbladder syndrome, and 122 patients with liver depression and spleen deficiency syndrome. Seventy-five commonly used clinical markers were selected, including liver and kidney function, clotting funct...
Source: Zhong xi yi jie he xue bao : Journal of Chinese Integrative Medicine. - December 1, 2012 Category: Complementary Medicine Authors: Bian YQ, Ning BB, Cao HY, Lu Y, Liu C, Chen GF, Liu J, Liu P, Sun MY Tags: Zhong Xi Yi Jie He Xue Bao Source Type: research

Diagnostic value of clinical indices in syndrome differentiation of chronic hepatitis B: an exploration based on receiver operating characteristic curves and stepwise discriminant analysis.
Abstract OBJECTIVE: To explore the diagnostic value of 75 commonly used clinical laboratory markers for differentiation of traditional Chinese medicine syndromes such as liver and gallbladder damp-heat and liver depression and spleen deficiency in patients with chronic hepatitis B. METHODS: A total of 422 patients with chronic hepatitis B (CHB) were enrolled, including 300 patients with damp-heat in liver and gallbladder syndrome, and 122 patients with liver depression and spleen deficiency syndrome. Seventy-five commonly used clinical markers were selected, including liver and kidney function, clotting funct...
Source: Zhong xi yi jie he xue bao : Journal of Chinese Integrative Medicine. - December 1, 2012 Category: Complementary Medicine Authors: Zhao Y, Peng JH, Li XM, Fu QL, Cui T, Li Q, Tang YJ, Feng Q, Zhang H, Zhou H, Hu YY Tags: Zhong Xi Yi Jie He Xue Bao Source Type: research

Occupational Medicine Aspects in General and Abdominal Surgery - Risk of Infection Attributable to Needlestick Injuries (What the Surgeon should Know).
Abstract Needlestick, stab, scratch, and cut injuries are a common problem and a significant health hazard among healthcare workers. The aim of this review is to give an overview on the risk of infection in general, abdominal and vascular surgery and to suggest occupational safety measures. Furthermore, we want to discuss insurance-related aspects. If medical devices are contaminated with blood or other body fluids, there is a relevant risk of infection with hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). The risk of transmission depends on the infection status of the pati...
Source: Zentralblatt fur Chirurgie - February 1, 2013 Category: Surgery Authors: Darius S, Meyer F, Boeckelmann I Tags: Zentralbl Chir Source Type: research

Mount Sinai researchers discover mechanism behind development of autoimmune hepatitis
(The Mount Sinai Hospital / Mount Sinai School of Medicine) A gene mutation disrupts the activity of certain immune cells and causes the immune system to erroneously attack the liver, according to a new animal study from the Icahn School of Medicine at Mount Sinai. The findings, published in the Journal of Clinical Investigation, will provide a new model for studying drug targets and therapies for Autoimmune Hepatitis.
Source: EurekAlert! - Medicine and Health - July 23, 2013 Category: Global & Universal Source Type: news

Mount Sinai researchers develop first successful laboratory model for studying hepatitis C
(The Mount Sinai Hospital / Mount Sinai School of Medicine) By differentiating monkey stem cells into liver cells and inducing successful infection, researchers from the Icahn School of Medicine at Mount Sinai have shown for the first time that the hepatitis C virus can replicate in monkeys, according to research published in the journal Gastroenterology.
Source: EurekAlert! - Medicine and Health - August 2, 2013 Category: Global & Universal Source Type: news

Investing in the Future of Medicine: A Investor's Guide to the In Vitro Diagnostics Market
In spite of all the advances we’ve made in medicine, people still get sick. But thankfully, we’re continuously getting better with our ability to diagnose. One clear way medicine is improving is the in vitro diagnostics (IVD) market — a subset of the overall medical technology market — which focuses on molecular diagnostics for conditions like infectious diseases, chronic diseases, sexually-transmitted diseases (STDs), oncology, and genetic testing. The better we get at figuring out what’s ailing people, the faster we can treat them. How big’s the in vitro diagnostics market and how fas...
Source: Forbes.com Healthcare News - February 12, 2014 Category: Pharmaceuticals Authors: Zack Miller Source Type: news

Hepatitis C remains major problem for HIV patients despite antiretroviral therapy
(University of Pennsylvania School of Medicine) A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has found that the risk of hepatitis C-associated serious liver disease persists in HIV patients otherwise benefiting from antiretroviral therapy to treat HIV.
Source: EurekAlert! - Medicine and Health - March 17, 2014 Category: Global & Universal Source Type: news

Hepatitis B virus infection in Latin America: A genomic medicine approach.
This article provides a critical view of the importance of genomic medicine for the study of HBV infection and its clinical outcomes in Latin America. Three levels of evolutionary adaptation may correlate with the clinical outcomes of HBV infection. Infections in Latin America are predominantly of genotype H in Mexico and genotype F in Central and South America; these strains have historically circulated among the indigenous population. Both genotypes appear to be linked to a benign course of disease among the native and mestizo Mexicans and native South Americans. In contrast, genotypes F, A and D are common in acute and ...
Source: World Journal of Gastroenterology : WJG - June 21, 2014 Category: Gastroenterology Authors: Roman S, Jose-Abrego A, Fierro NA, Escobedo-Melendez G, Ojeda-Granados C, Martinez-Lopez E, Panduro A Tags: World J Gastroenterol Source Type: research

Temporal abstraction and temporal Bayesian networks in clinical domains: A survey
Conclusion The main conclusion transpiring from this review is that techniques/methods from these two areas, that so far are being largely used independently of each other in clinical domains, could be effectively integrated in the context of medical decision-support systems. The anticipated key benefits of the perceived integration are: (a) during problem solving, the reasoning can be directed at different levels of temporal and/or conceptual abstractions since the nodes of the TBNs can be complex entities, temporally and structurally and (b) during model building, knowledge generated in the form of basic and/or complex a...
Source: Artificial Intelligence in Medicine - October 12, 2014 Category: Bioinformatics Source Type: research

The effect of HCV serological status on Doxorubicin based chemotherapy induced toxicity and disease-free survival in breast cancer patients
Conclusion Patients receiving chemotherapy should undergo screening for the virus. Most patients with HCV were able to tolerate chemotherapy and continue the initial chemotherapy plan, without a significant change in the toxicity profile or the natural course of their malignancy. Dose or regimen adjustments may be of help to less tolerant patients. A preemptive 10% initial Doxorubicin dose reduction might reduce the frequency of severe toxicity for selected patients. The assistance of a gastroenterologist in HCV positive breast cancer patients, planned for chemotherapy is important.
Source: Alexandria Journal of Medicine - October 22, 2014 Category: Journals (General) Source Type: research

New Drugs in 2013
Publication date: January 2015 Source:Hospital Medicine Clinics, Volume 4, Issue 1 Author(s): Jared Grochowsky , Joseph Ming Wah LiTeaser Many new promising drugs emerged in 2013, including breakthroughs in the area of cancer, diabetes, pulmonary hypertension, hepatitis C, and multiple sclerosis treatment. Many of the trends in drug approval, including most of the drugs approved for oncologic diagnoses, are similar to previous years; however, there have also been drugs that are novel in their action to treat their respective diseases. Six new drugs were chosen and are reviewed due to their potential relevance to hospital...
Source: Hospital Medicine Clinics - November 30, 2014 Category: Internal Medicine Source Type: research

Simeprevir-based therapy offers cost-effective alternative in treatment of hepatitis C
(University of Pennsylvania School of Medicine) Researchers at Penn Medicine, in collaboration with an international team, have shown that a protease inhibitor, simeprevir, along with interferon and ribavirin is as effective in treating chronic Hepatitis C virus infection as telaprevir with interferon and ribavirin, the standard of care in developing countries. Further, simeprevir proved to be simpler for patients and had fewer adverse events. The complete study is online and is scheduled to publish in January 2015 in The Lancet Infectious Diseases.
Source: EurekAlert! - Medicine and Health - December 9, 2014 Category: Global & Universal Source Type: news

Implementing hospital‐based baby boomer hepatitis c virus screening and linkage to care: Strategies, results, and costs
CONCLUSIONSThis inpatient HCV screening program diagnosed chronic HCV infection in 4.2% of tested patients and linked >80% to follow‐up care. Yet access to therapy is challenging for largely uninsured populations, and most programmatic costs of the program are not currently covered. Journal of Hospital Medicine 2015. © 2015 Society of Hospital Medicine
Source: Journal of Hospital Medicine - May 29, 2015 Category: Hospital Management Authors: Barbara J. Turner, Barbara S. Taylor, Joshua T. Hanson, Mary Elizabeth Perez, Ludivina Hernandez, Roberto Villarreal, Poornachand Veerapaneni, Kristin Fiebelkorn Tags: Original Research Source Type: research

Serum cytokine profiling analysis for zheng differentiation in chronic hepatitis B
This study aims to investigate the changes in cytokines and their profiles accompanied by different biological responses in LGDH and LKYD in CHB. Methods: During 2010–2012, a total of 138 morning fasting venous blood samples were obtained from participants in Shuguang Hospital, Shanghai University of Traditional Chinese Medicine in Shanghai, China. First, serum samples from 20 health controls (HCs) and 40 CHB patients (20 LGDH, 20 LKYD) were collected to detect the profiles of cytokines by multiplex biometric ELISA-based immunoassay. Random forest (RF) with a fivefold cross-validation was used to analyze the significant ...
Source: Chinese Medicine - August 27, 2015 Category: Complementary Medicine Authors: Yi-Yu LuYu ZhaoYa-Nan SongShu DongBin WeiQi-Long ChenYi-Yang HuShi-Bing Su Source Type: research

A Medical Student-Driven "Vaccine Blitz" at a School-Based Health Center as an Effective Way to Improve Adolescent Vaccination Rates.
CONCLUSIONS: Medical student-driven vaccine blitzes within an SBHC are a feasible, replicable, and effective way to increase adolescent vaccination rates. In addition, the blitz provided preclinical medical students' exposure to underserved populations, adolescent health as part of the breadth of family medicine, SBHCs, and community medicine and allowed for multidisciplinary work between medical students, public health students, physicians, and nurse practitioners. PMID: 26562643 [PubMed - as supplied by publisher]
Source: Family Medicine - November 13, 2015 Category: Primary Care Tags: Fam Med Source Type: research