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Infectious Disease: Hepatitis

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Total 12583 results found since Jan 2013.

Postmortem Diagnosis of Cytomegalovirus and Accompanying Other Infection Agents by Real-Time PCR in Cases of Sudden Unexpected Death in Infancy (SUDI)
Publication date: Available online 23 November 2015 Source:Journal of Forensic and Legal Medicine Author(s): Gulhan Yagmur, Nihan Ziyade, Neval Elgormus, Taner Das, M.Feyzi Sahin, Muzaffer Yildirim, Ayse Ozgun, Arzu Akcay, Ferah Karayel, Sermet Koc As an opportunistic pathogen with high mortality rates, Cytomegalovirus (CMV) may lead to fatal disseminated CMV infection of the premature and newborn; thus necessitating the demonstration of CMV-DNA with clinical history and/or histopathological findings of CMV infection and defining other bacterial and viral infection agents with real-time polymerase chain reactio...
Source: Journal of Forensic and Legal Medicine - November 25, 2015 Category: Forensic Medicine Source Type: research

Update in adolescent gastroenterology.
Authors: Atay O Abstract Pediatric gastroenterology, just as all fields within pediatrics, focuses on the unique needs of children ranging from infancy to adolescence. Although there is some overlap between adult gastroenterology and pediatric gastroenterology, these are 2 distinct fields of medicine that address the specific health care needs of the demographics they serve. The purpose of this article is to address several medical issues that have a particular importance to the pediatric population. The 5 main topics of discussion are magnet ingestion, cannabinoid hyperemesis syndrome, obesity and how it pertains ...
Source: Adolescent Medicine: State of the Art Reviews - December 20, 2015 Category: Pediatrics Tags: Adolesc Med State Art Rev Source Type: research

The Preventive Effect on Ethanol-Induced Gastric Lesions of the Medicinal Plant Plumeria rubra: Involvement of the Latex Proteins in the NO/cGMP/K ATP Signaling Pathway.
This study shows that proteins extracted from the latex of P. rubra prevent gastric lesions induced in experimental animals. Also, the results support the use of the plant in folk medicine. PMID: 26788111 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - January 22, 2016 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Short-term efficacy of treating hepatitis B virus-related acute-on-chronic liver failure based on cold pattern differentiation with hot herbs: A randomized controlled trial
Conclusions The integrative treatment of CM and WM was effective and safe for HBV-ACLF patients with cold pattern in CM. The Chinese therapeutic principle "treating cold pattern with hot herbs" remains valuable to the clinical therapy. (Trial registration No. ChiCTR-TRC-10000766)
Source: Chinese Journal of Integrative Medicine - May 23, 2016 Category: Internal Medicine Source Type: research

Results from Merck ’s Phase 3 Study Evaluating ZEPATIER™ (elbasvir and grazoprevir) in Patients with Chronic Hepatitis C Receiving Treatment for Opioid Dependence Published in Annals of Internal Medicine
Dateline City: KENILWORTH, N.J.KENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced the publication of results fromC-EDGE CO-STAR.C-EDGE CO-STAR is a Phase 3 trial evaluating the use of ZEPATIER ™ (elbasvir and grazoprevir) 50mg/100mg tablets in patients with chronic hepatitis C (HCV) genotype (GT) 1, GT4 and GT6 infection receiving opioid agonist therapy (OAT) (methadone and buprenorphine), commonly used to treat opioid addiction.Language: EnglishContact: MerckMedia:Pamela Eisele, 267-305-3558orSarra Herzog, 201-669-6570...
Source: Merck.com - Product News - August 8, 2016 Category: Drugs & Pharmacology Tags: Hepatitis C Newsroom Prescription Medicine News Research and Development News Corporate News Latest News #Merck #MRK $MRK Annals of Internal Medicine MSD ZEPATIER Source Type: news

Hepatoprotective effect of quercetin: From chemistry to medicine.
Abstract Liver diseases caused by viral hepatitis infections have a negative impact on global health. Approximately 30 million people in the USA and 29 million people in the European Union suffer from chronic liver disease. There are many kinds of diseases of the liver, caused by viruses, such as hepatitis A, hepatitis B and hepatitis C, or by certain drugs and poisons including excessive alcohol consumption. Many herbal medicines are used in traditional medicine for their protective and therapeutic properties against liver diseases. Among their bioactive components, flavonoids have been found to be active against...
Source: Food and Chemical Toxicology - August 30, 2016 Category: Food Science Authors: Miltonprabu S, Tomczyk M, Skalicka-Woźniak K, Rastrelli L, Daglia M, Nabavi SF, Alavian SM, Nabavi SM Tags: Food Chem Toxicol Source Type: research

The Use of Hijama (Wet Cupping) in Alternative and Complementary Medicine: Efficacious or Perilous?
Publication date: Available online 10 September 2016 Source:Journal of Acupuncture and Meridian Studies Author(s): Syed Mohammad Mazhar Uddin, Aatera Haq, Haris Sheikh The field of medicine has remained an extensive ground for major advancements over recent decades with the primary purpose of reducing the suffering of humanity and improving the course of life. However, despite these modern advancements, the popularity of complementary and alternative medicine (CAM) has increased. The use of CAM in many developed and developing countries is considerable. One such example of CAM is Hijama, which literally means sucking (cup...
Source: Journal of Acupuncture and Meridian Studies - September 10, 2016 Category: Complementary Medicine Source Type: research

Expanding access: First clinical trial transplants hepatitis C-infected kidneys at Penn Medicine
(University of Pennsylvania School of Medicine) Patients who need a kidney transplant may have new hope, through an innovative Penn Medicine clinical trial using kidneys from deceased donors who had the hepatitis C virus (HCV). The first study participant received a kidney transplant in July 2016, and after being treated with a full regimen of Zepatier -- a recently-approved oral medication prescribed to eradicate HCV -- her doctors announced today that there is no evidence of the virus in her blood.
Source: EurekAlert! - Infectious and Emerging Diseases - September 13, 2016 Category: Infectious Diseases Source Type: news

Oral Combination Therapies for Hepatitis C Virus Infection: Successes, Challenges, and Unmet Needs.
Abstract The current standard of care for the treatment of hepatitis C virus (HCV) consists of interferon-free direct-acting antiviral (DAA) regimens, including combinations of DAAs and fixed-dose combination pills. DAAs for HCV are likely to be heralded as one of medicine's greatest advancements. Viral eradication rates are pushing 100% for many HCV-infected populations, including patients with HIV/HCV coinfection, decompensated cirrhosis, liver and kidney transplants, and end-stage liver disease. We highlight the greatest successes of combination DAA therapies, discuss the ongoing challenges, and identify the re...
Source: Annual Review of Medicine - September 22, 2016 Category: Journals (General) Authors: Naggie S, Muir AJ Tags: Annu Rev Med Source Type: research

iTRAQ-Based Proteomics Identification of Serum Biomarkers of Two Chronic Hepatitis B Subtypes Diagnosed by Traditional Chinese Medicine.
Conclusion. This is the first time to report serum proteins in CHB subtype patients. Our findings provide potential biomarkers can be used for LSSD-CHB and DHSM-CHB. PMID: 28025641 [PubMed - in process]
Source: Biomed Res - December 28, 2016 Category: Research Authors: Yang J, Yang L, Li B, Zhou W, Zhong S, Zhuang Z, Yang B, Chen M, Feng Q Tags: Biomed Res Int Source Type: research

Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
This study aimed to assess the frequency of use, utilization patterns, and therapeutic effects of adjuvant CHM for ischemic heart disease (IHD) in patients with T2D in Taiwan. We identified 4620 IHD patients with T2D. After matching for age, gender, and insulin use, 988 subjects each were allocated to a CHM group and a non-CHM group. There were no differences in baseline characteristics except for comorbidities. The CHM group contained more cases with chronic obstructive pulmonary disease, hepatitis, ulcer disease, and hyperlipidemia. The cumulative survival probability was higher in CHM users than in matched non-CHM users...
Source: Oncotarget - January 19, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

The use of Chinese herbal medicine as an adjuvant therapy to reduce incidence of chronic hepatitis in colon cancer patients: A Taiwanese population-based cohort study
Conclusions This nationwide retrospective cohort study determined that therapy using CHM as an adjuvant modality may have a significant impact on liver protection in patients with colon cancer. Graphical abstract
Source: Journal of Ethnopharmacology - March 23, 2017 Category: Drugs & Pharmacology Source Type: research

New report lays plan to eliminate 90,000 hepatitis B and C deaths by 2030
(National Academies of Sciences, Engineering, and Medicine) Hepatitis B and C kill more than 20,000 people every year in the United States. A new report from the National Academies of Sciences, Engineering, and Medicine presents a strategy to eliminate these diseases as serious public health problems and prevent nearly 90,000 deaths by 2030.
Source: EurekAlert! - Medicine and Health - March 28, 2017 Category: Global & Universal Source Type: news

Risk perception of hepatitis B infection and uptake of hepatitis B vaccine among students of tertiary institution in Jos
Conclusions: Awareness and risk perception on HBV infection are high among University of Jos students, but uptake of HB vaccine is low. Findings are worst for non-health students.
Source: Annals of African Medicine - April 27, 2017 Category: African Health Authors: MP Chingle IA Osagie H Adams D Gwomson N Emeribe AI Zoakah Source Type: research

Conflicts of Interest Reported in an Abbreviated Time Frame
To the Editor In their Original Investigation in a recent issue ofJAMA Internal Medicine, Jefferson and Pearson reported on adherence to Institute of Medicine (IOM) conflict of interest standards in the American Association for the Study of Liver Diseases and Infectious Diseases Society of America (AASLD/IDSA) Recommendations for Testing, Managing, and Treating Hepatitis C.
Source: JAMA Internal Medicine - July 1, 2017 Category: Internal Medicine Source Type: research