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Infectious Disease: Hepatitis
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Emergency department experiences of people who use drugs who left or were discharged from hospital against medical advice
ConclusionsStructural vulnerabilities in ED can negatively impact the care received among PWUD. Findings demonstrate the need to consider how structural factors impact care for PWUD and to leverage existing infrastructure to incorporate harm reduction and a structural competency focused care. Findings also point to the need to consider how withdrawal and pain are managed in emergency department settings.
Source: PLoS One - February 23, 2023 Category: Biomedical Science Authors: Samara Mayer Source Type: research
Primary Hepatic Angioleiomyoma: A Case Report
CONCLUSIONS Clinically, primary hepatic angioleiomyoma should be distinguished from other types of liver tumors, especially liver cancer. In combination with our long-term observation and other case reports, we recommend general follow-up if the preoperative pathological diagnosis can be confirmed and the patient has no other symptoms.PMID:36805667 | PMC:PMC9944988 | DOI:10.12659/AJCR.938645
Source: Pain Physician - February 22, 2023 Category: Anesthesiology Authors: Tsengelmaa Jamiyan Hajime Kuroda Ganchudur Luvsan Tserennadmid Munkhnyam Akinari Kakumoto Bayarmaa Enkhbat Source Type: research
Unusual Case Presentation of Genital Herpes
CONCLUSION The process of removing nonviable tissue is called debridement. Debridement is only necessary when a herpetic ulceration is not healing on its own, which is when necrotic tissue that can harbor bacteria that may cause more extensive infections is formed. Removing the necrotic tissue speeds up healing and reduces the risk of further complications.PMID:36812284
Source: Herpes - February 22, 2023 Category: Infectious Diseases Authors: Magdalena Matak Luka Matak Source Type: research
Primary Hepatic Angioleiomyoma: A Case Report
CONCLUSIONS Clinically, primary hepatic angioleiomyoma should be distinguished from other types of liver tumors, especially liver cancer. In combination with our long-term observation and other case reports, we recommend general follow-up if the preoperative pathological diagnosis can be confirmed and the patient has no other symptoms.PMID:36805667 | DOI:10.12659/AJCR.938645
Source: Cancer Control - February 22, 2023 Category: Cancer & Oncology Authors: Tsengelmaa Jamiyan Hajime Kuroda Ganchudur Luvsan Tserennadmid Munkhnyam Akinari Kakumoto Bayarmaa Enkhbat Source Type: research
New Treatment Paradigms in Primary Biliary Cholangitis
Primary biliary cholangitis (PBC) is an archetypal autoimmune disease. Chronic lymphocytic cholangitis is associated with interface hepatitis, ductopenia, cholestasis and a progressive biliary fibrosis. People living with PBC are frequently symptomatic, experiencing a quality-of-life burden dominated by fatigue, itch, abdominal pain, and sicca complex. Whilst the female predominance, specific serum autoantibodies, immune mediated cellular injury, as well as genetic (HLA and non-HLA) risk factors, identify PBC as autoimmune, to date treatment has focused on cholestatic consequences.
Source: Clinical Gastroenterology and Hepatology - February 18, 2023 Category: Gastroenterology Authors: Cynthia Levy, Michael Manns, Gideon Hirschfield Source Type: research
Hepatic epithelioid angiomyolipoma is scattered and unsuitable for surgery: a case report
J Int Med Res. 2023 Feb;51(2):3000605231154657. doi: 10.1177/03000605231154657.ABSTRACTHepatic epithelioid angiomyolipoma (HEAML) is a rare tumour of mesenchymal tissue with a malignant tendency. Occurring most frequently in women, the relative incidence in men and women, according to incomplete statistics, is approximately 1:5. In rare cases, disease occurrence and development is hidden. Lesions are generally discovered as chance findings by patients; abdominal pain is the first symptom, and imaging has no specificity in diagnosing the disease. Therefore, great difficulties exist in the diagnosis and treatment of HEAML. H...
Source: Cell Research - February 16, 2023 Category: Cytology Authors: Xiangreng Cai Shuchuan Sun Yuxin Deng Jiangxin Liu Siyuan Pan Source Type: research
Multiple Duodenal Polyps in a Young Patient With Liver Cirrhosis
A woman in her mid-20s with recently decompensated liver cirrhosis secondary to autoimmune hepatitis was evaluated for liver transplantation. Esophagogastroduodenoscopy was performed to screen for esophageal/gastric varices. The patient had nonspecific mild abdominal pain and dyspepsia without diarrhea or constipation. Laboratory findings were remarkable for iron deficiency anemia with a hemoglobin level of 9.5 g/dL and a ferritin level of 10 μg/L. Esophagogastroduodenoscopy revealed multiple pedunculated polyps with superficial ulcerations ranging in size from 8 to 20 mm throughout the second part of the duodenum (Figure 1).
Source: Mayo Clinic Proceedings - February 1, 2023 Category: Internal Medicine Authors: Manar Shmais, Hassan Dagher, Ala I Sharara Tags: Medical image Source Type: research
Assessment of risk factors associated with outbreak of hepatitis A in Shakrial, Rawalpindi, Pakistan
Conclusions: Healthcare departments should implement public policies towards the management of hepatitis A in Pakistan. Health awareness sessions and vaccination for children ≤ 16 years age is recommended.
Source: The Journal of Infection in Developing Countries - January 31, 2023 Category: Infectious Diseases Authors: Aamir Badar, Muhammad Wasif Malik, Syed Zain Hasnain, Syed Ijaz Ali Shah, Rana Muhammad Kamran Shabbir, Waseem Haider, Haroon Ahmed Source Type: research
Janssen Announces Unblinding of Phase 3 CARTITUDE-4 Study of CARVYKTI ® (cilta-cel) as Primary Endpoint Met in Treatment of Patients with Relapsed and Refractory Multiple Myeloma
RARITAN, New Jersey, January 27, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Phase 3 CARTITUDE-4 study evaluating CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) versus pomalidomide, bortezomib, and dexamethasone (PVd) or daratumumab, pomalidomide, and dexamethasone (DPd) for the treatment of patients with relapsed and lenalidomide-refractory multiple myeloma met its primary endpoint of significant improvement in progression-free survival (PFS) at the first pre-specified interim analysis. As a result of meeting the primary endpoint, the Independent Data Monitoring Commi...
Source: Johnson and Johnson - January 27, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Hepatocellular carcinoma presenting as right shoulder pain
We report an uncommon presentation of liver cancer in a 33-year-old woman who presented with persistent right shoulder pain with a normal physical examination of her shoulder and normal X-rays. An abdominal ultrasound scan and a computed tomography scan subsequently revealed a large liver cancer in this patient who was subsequently found to be hepatitis B positive. Extrinsic causes of shoulder pain should be considered when shoulder movement is normal and does not alter the character of the pain. Subdiaphragmatic liver lesions should be considered in the differential diagnosis of right shoulder pain. In any geographical ar...
Source: Annals of African Medicine - January 24, 2023 Category: African Health Authors: Senyo Tagboto Source Type: research
Tenofovir-induced osteopenia and hyperparathyroidism: A case report and literature review
In this report, we describe the differences in clinical and laboratory manifestations of hyperparathyroidism induced by tenofovir disoproxil fumarate and normocalcemic primary hyperparathyroidism. We also discuss relevant pathophysiological mechanisms and propose a feasible treatment strategy.
Source: Frontiers in Endocrinology - January 11, 2023 Category: Endocrinology Source Type: research
Simultaneous infection of amoebic liver abscess and hepatitis A infection in a young adult in an endemic region
We report a case of a young female with simultaneous infection of HAV and amoebic liver abscess, emphasizing the role of dual infection and its clinical manifestations.PMID:36618234 | PMC:PMC9810883 | DOI:10.4103/jfmpc.jfmpc_149_22
Source: Primary Care - January 9, 2023 Category: Primary Care Authors: Saurabh Puri Gulshan Singh Randhawa Sukriti Bhasin Rajat Aggarwal Parkash Gera Source Type: research
Pain at Hepatitis B Vaccine in Preterm Infants
Condition: Infant, Newborn, Pain Intervention: Behavioral: Palmar grasp reflex Sponsors: Ataturk University; MSc Elif Simay KOÇ Recruiting
Source: ClinicalTrials.gov - January 5, 2023 Category: Research Source Type: clinical trials
