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Infectious Disease: Hepatitis
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Total 33382 results found since Jan 2013.
Roche ’s Tecentriq in combination with Avastin approved in China for people with the most common form of liver cancer
Basel, 29 October 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the China National Medical Products Administration (NMPA) has approved Tecentriq® (atezolizumab) in combination with Avastin® (bevacizumab) for the treatment of people with unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy.“Today’s approval of Tecentriq in combination with Avastin for unresectable hepatocellular carcinoma means that people in China now have a cancer immunotherapy option which is changing the treatment landscape for this aggressive disease”, said Levi Ga...
Source: Roche Investor Update - October 29, 2020 Category: Pharmaceuticals Source Type: news
European Commission approves Roche ’s Tecentriq in combination with Avastin for the treatment of people with the most common form of liver cancer
Basel, 2 November 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Commission has approved Tecentriq ® (atezolizumab) in combination with Avastin® (bevacizumab) for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy.“Tecentriq in combination with Avastin is the first treatment to be approved in over a decade that has improved overall survival for people with previously untreated advanced or unresectable hepatocellular carcinoma,” said Levi Garraway, M.D., Ph.D., Roche’s Chief Medical Officer and Head of...
Source: Roche Media News - November 2, 2020 Category: Pharmaceuticals Source Type: news
Spontaneous reports of primary ovarian insufficiency after vaccination: A review of the vaccine adverse event reporting system (VAERS)
CONCLUSIONS: POI is rarely reported to VAERS. Most reports contained limited diagnostic information and were submitted after published cases of POI following HPV vaccination. Results of our review do not suggest a safety concern.PMID:36732165 | DOI:10.1016/j.vaccine.2022.12.038
Source: Vaccine - February 2, 2023 Category: Allergy & Immunology Authors: A Patricia Wodi Paige Marquez Adamma Mba-Jonas Faith Barash Kosal Nguon Pedro L Moro Source Type: research
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Prevalence of hepatitis C in patients with renal disease undergoing hemodialysis treatment
This study aimed at determining the prevalence of hepatitis C among 649 patients diagnosed with chronic or acute kidney disease − patients were undergoing hemodialysis treatment at a large hemodialysis center in Porto Alegre-RS, from January through December, 2012 –, as well as relating our data to that presented in the national census, reporting cases of coinfection by hepatitis C and human immunodeficiency virus (HIV), and defining the demographic profile of these patients. Method: An observational cross-sectional study was conducted and data was obtained from information in patients’ electronic medical records. ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 14, 2014 Category: Pathology Source Type: research
Epidemiological analysis of serological markers of hepatitis B in HIV+ patients from Curitiba and metropolitan region
Conclusion: The findings of the present study corroborate the need to investigate systematically the presence of markers for HBV in HIV+ patients from different regions of the country. Introdução: A presença do vírus da hepatite B (HBV) em indivíduos infectados pelo vírus da imunodeficiência humana (HIV) está associada ao significante aumento da morbimortalidade nos pacientes afetados. Objetivo: Estabelecer a prevalência de marcadores sorológicos de HBV e dos fatores epidemiológicos associados em pacientes HIV+ acompanhados pelo Hospital de Clínicas da Universidade Federal do Paraná (HC-UFPR). Métodos: Os dad...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - May 22, 2015 Category: Pathology Source Type: research
Between evidence and negligence: coverage and invisibilityof health topics in the Portuguese printed media
Este estudo objetiva realizar uma análise sobre a divulgação midiática da saúde em Portugal, a fim de problematizar as questões da cobertura e invisibilidade dos temas de saúde, as quais apontariam Temas Midiaticamente Negligenciados. Para tanto, foram comparadas a cobertura de saúde do Jornal Público com o contexto epidemiológico sobre as prioridades de saúde e com as percepções dos atores-chave acerca da divulgação midiática e dos temas relevantes à população portuguesa. Evidenciou-se nos resultados que os temas ligados à saúde mais recorrentes na mídia portuguesa não se referem às doenças propri...
Source: Ciencia e Saude Coletiva - November 24, 2015 Category: Occupational Health Source Type: research
Collapsing variant of focal segmental glomerulosclerosis by parvovirus B19: case report.
CONCLUSION: There is demonstrated the temporal association of PVB19 viremia and collapsing FSGS, due primary infection or viral reactivation. The association of collapsing FSGS and PVB19 is described in the literature, demonstrating virus presence in kidney tissue, but the real relationship of virus in the pathogenesis of this glomerulopathy remains unclear.
PMID: 25923759 [PubMed - in process]
Source: Jornal Brasileiro de Nefrologia - December 21, 2015 Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Medtech approvals: FDA releases December 2015 PMAs
The Food & Drug Administration today released a list of pre-market approvals granted in December 2015:
Summary of PMA Originals & Supplements Approved
Originals: 2
Supplements: 81
Summary of PMA Originals Under Review
Total Under Review: 58
Total Active: 32
Total On Hold: 26
Summary of PMA Supplements Under Review
Total Under Review: 599
Total Active: 423
Total On Hold: 176
Summary of All PMA Submissions
Originals: 3
Supplements: 92
Summary of PMA Supplement PMA Approval/Denial Decision Times
Number of Approvals: 81
Number of Denials: 0
Average Days Fr Receipt to Decision (Total Time): 163.1
FDA Time: 140....
Source: Mass Device - February 2, 2016 Category: Medical Equipment Authors: MassDevice Tags: Food & Drug Administration (FDA) Regulatory/Compliance Source Type: news
Fight Aging! Newsletter, May 16th 2016
In this study the authors demonstrate that, as in many other cases, the methodology of delivery matters just as much as the details of the cells used:
Retinal and macular degenerative diseases affect millions of people worldwide. Similar to other neurodegenerative diseases, there are no effective treatments that can stop retinal degeneration or restore degenerative retina. Recent advances in stem cell technology led to development of novel cell-based therapies, some are already in phase I/II clinical trials. Studies from our group and others suggest that human bone marrow-derived mesenchymal stem cells (hBM-MSC) m...
Source: Fight Aging! - May 15, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Histopathological study comparing native and post-transplant recurrent chronic hepatitis C with emphasis on confounders with acute cellular rejection
Conclusion: Histological findings in chronic hepatitis C are similar in non-transplant and post-transplant patients. In addition, morphological features characteristic of ACR are also observed in HCV infection of native livers as well as in the graft of patients with recurrent infection after transplantation.RESUMO Introdu ção: A análise histológica de biópsias hepáticas pós-transplante pode trazer dificuldades na distinção entre hepatite crônica C (HCC) recorrente e outras causas de disfunção do enxerto, sobretudo rejeição celular aguda (RCA). Objetivo: Comparar as características histológicas de bió psia...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - December 9, 2016 Category: Pathology Source Type: research
HBV and HCV serological markers in health professionals and users of the Brazilian Unified Health System network in the city of Resende, Rio de Janeiro, Brazil
Conclusion: The prevalence of 0.68% for HCV and 3.08% for anti-HBc are below that detected in the Southeast region from the last census in the capitals of Brazil. There is still a reduced acceptance among health professi onals for HBV and HCV screening.RESUMO Introdu ção: As infecções causadas pelo vírus da hepatite B (VHB) e C (VHC) constituem grave problema de saúde pública. Objetivos: O estudo visou detectar os marcadores HBsAg, anti-HBc, anti-HBs e anti-VHC em profissionais de saúde e usuários do Sistema Único de Saúde (SUS) no município de Rese nde, Rio de Janeiro, bem como descrever o perfil sociodemográ...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - May 19, 2017 Category: Pathology Source Type: research
