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Infectious Disease: Hepatitis

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Total 33382 results found since Jan 2013.

Infection, Infectious Agents and Vascular Disease
CONCLUSION: Infectious agents may affect vessel's homeostasis and functionality, both on the arterial and venous side, by means of several pathophysiological mechanisms such as dysregulation in vasomotor function, thromboembolic complications, initiation and progression of atherosclerosis, alteration of perivascular adipose tissue, recruiting inflammatory cells and molecules.PMID:33823769 | DOI:10.2174/1574887116666210325124045
Source: Reviews on Recent Clinical Trials - April 7, 2021 Category: Cancer & Oncology Authors: Nicola Ielapi Francesco Caprino Biagio Malizia Antonio Sisinni Lwanga Ssempijja Ssempijja Michele Andreucci Noemi Licastro Raffaele Serra Source Type: research

Vascular invasion in hepatitis B virus-related hepatocellular carcinoma with underlying cirrhosis: possible associations with ascites and hepatitis B viral factors?
The objective of the current, retrospective study was to determine the associations of ascites and hepatitis B viral factors (HBeAg and anti-HBe status and HBV DNA levels), as well as tumor-related factors (size, tumor number, grade, and location) with micro- or macroscopic vascular invasion in patients with HCC that developed as a result of hepatitis B virus (HBV)-related cirrhosis. A total of 336 consecutive patients were included. Potential factors associated with micro- or macroscopic vascular invasion were analyzed by logistic regression. Ascites were more commonly detected in patients with micro- or macroscopic vascu...
Source: Tumor Biology - April 2, 2015 Category: Cancer & Oncology Source Type: research

Chronic hepatitis B infection is not associated with increased risk of vascular mortality while having an association with metabolic syndrome
This study aimed to assess the association of chronic hepatitis B (CHB) with vascular mortality and metabolic syndrome (MS) using data from a large population‐based cohort study in Iran.A total of 12,781 participants (2249 treatment‐naïve CHB and 10,532 without CHB) were studied. Logistic regression model was used to assess the association between MS and CHB with adjustment for age, ALT, PLT, alcohol intake, smoking, exercise, and socioeconomic status. MS was defined according to the ATPIII guidelines. Cox proportional hazards model was used to assess the hazard ratios for overall and vascular related mortality.There ...
Source: Journal of Medical Virology - January 7, 2016 Category: Virology Authors: A Katoonizadeh, S Ghoroghi, M Sharafkhah, M Khoshnia, S Mirzaei, A Shayanrad, H Poustchi, R. Malekzadeh Tags: Research Article Source Type: research

Visualizing the hepatic vascular architecture using superb microvascular imaging in patients with hepatitis C virus: A novel technique.
CONCLUSION: SMI permitted the detailed delineation of the vascular architecture in chronic liver disease. SMI appears to be a reliable tool for noninvasively detecting significant fibrosis or cirrhosis in HCV patients. PMID: 27468197 [PubMed - as supplied by publisher]
Source: World Journal of Gastroenterology - July 13, 2016 Category: Gastroenterology Authors: Kuroda H, Abe T, Kakisaka K, Fujiwara Y, Yoshida Y, Miyasaka A, Ishida K, Ishida H, Sugai T, Takikawa Y Tags: World J Gastroenterol Source Type: research

Autotaxin and vascular endothelial growth factor receptor ‐2 and ‐3 are related to vascular development during the progression of chronic viral hepatitis C
This study examines whether these two angiogenic factors cooperate in the mechanism that regulates vascular development during the progression of chronic viral hepatitis C (CVH ‐C) (Inuyama classification, F1–F4). First, surgical wedge biopsy specimens and needle biopsy specimens were obtained. Immunohistochemical staining for ATX and vascular endothelial growth factor receptor was assessed in serial sections. Immunoelectron microscopy was conducted with a perfusion‐ fixation method. In normal control liver tissue specimens, ATX was expressed at low levels within the branches of the hepatic artery and hepatic sinusoi...
Source: APMIS - November 19, 2018 Category: Research Authors: Hiroaki Yokomori, Wataru Ando, Fumihiko Kaneko, Hidekazu Suzuki, Koji Igarashi, Masaya Oda Tags: Original Article Source Type: research

Matrine attenuates high-fat diet-induced in vivo and ox-LDL-induced in vitro vascular injury by regulating the PKC α/eNOS and PI3K/Akt/eNOS pathways.
Matrine attenuates high-fat diet-induced in vivo and ox-LDL-induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways. J Cell Mol Med. 2019 Feb 15;: Authors: Zhang S, Guo S, Gao XB, Liu A, Jiang W, Chen X, Yang P, Liu LN, Shi L, Zhang Y Abstract Lipid metabolism disorders lead to vascular endothelial injury. Matrine is an alkaloid that has been used to improve obesity and diabetes and for the treatment of hepatitis B. However, its effect on lipid metabolism disorders and vascular injury is unclear. Here, we investigated the effect of matrine on high-fat diet fed mice and...
Source: J Cell Mol Med - February 15, 2019 Category: Molecular Biology Authors: Zhang S, Guo S, Gao XB, Liu A, Jiang W, Chen X, Yang P, Liu LN, Shi L, Zhang Y Tags: J Cell Mol Med Source Type: research

Exploring the Link Between Platelet Numbers and Vascular Homeostasis Across Early and Late Stages of Fibrosis in Hepatitis C
ConclusionIn chronic HCV, progressive decline in platelets and growth factors with fibrosis and their associations suggest that platelets are an important source of circulating GFs and influence GF decline with fibrosis. Enhanced markers of vascular injury in patients with early fibrosis suggest an earlier onset of endothelial dysfunction preceding cirrhosis. Associations of VIMs with platelets suggest a critical link between platelets and vascular homeostasis. Circulating markers of vascular injury may not only have prognostic importance but emphasize the role of vascular dysfunction in liver disease pathogenesis (NCT00001971).
Source: Digestive Diseases and Sciences - August 11, 2019 Category: Gastroenterology Source Type: research

Malpositioned endoscopically inserted biliary stent causing massive hematemesis managed with vascular plug and stenting
Diagn Interv Radiol. 2021 Nov;27(6):789-791. doi: 10.5152/dir.2021.20776.ABSTRACTA 46-year-old man with a history of hepatitis B cirrhosis and hepatocellular carcinoma (HCC) status post liver transplantation two years ago complicated by HCC recurrence and biliary stenosis presented with hypovolemic shock and melena one month after endoscopic exchange of plastic biliary stents. During endoscopic retrograde cholangiopancreatography, patient was found to have hemobilia and developed uncontrollable bleeding after a common bile duct (CBD) sweep managed by insertion of a stent-graft across major papilla into presumed CBD. The bl...
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - November 18, 2021 Category: Radiology Authors: Mark A Reddick Andrew J Ceranske Peiman Habibollahi Source Type: research