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Infectious Disease: Tuberculosis

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Action Needed to Avoid the End of Modern Medicine
This study influenced the development of the WHO’s new  guidelines, which are aimed at influencing policy makers in the agriculture and health sectors.   According to a WHO press release, the guidelines include:An overall reduction in the use of all classes of medically important antibiotics in food-producing animals.Complete restriction of these antibiotics for growth promotion and for disease prevention without diagnosis.Healthy animals should only receive antibiotics to prevent disease if it has been diagnosed in other animals in the same flock or herd or fish population.Antibiotics used in animals should be from t...
Source: IPS Inter Press Service - Health - December 5, 2017 Category: International Medicine & Public Health Authors: Martin Khor Tags: Development & Aid Global Governance Headlines Health Poverty & SDGs TerraViva United Nations Source Type: news

Study on physical properties of Ayurvedic nanocrystalline Tamra Bhasma by employing modern scientific tools
Conclusion Scientific data obtained using modern scientific tools and evidence would support in utilizing the ancient Indian wisdom of Ayurveda for the development of newer drugs as a modern nanomedicine and in other possible technological applications.
Source: Journal of Ayurveda and Integrative Medicine - December 15, 2017 Category: Complementary Medicine Source Type: research

Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America
The Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America clinical practice guideline is intended to guide clinicians caring for solid-organ transplant (SOT) donors, candidates and recipients regarding infectious diseases (ID) issues related to this geographical region, mostly located in the tropics. These recommendations are based on both systematic reviews of relevant literature and expert opinion from both transplant ID and travel medicine specialists. The guidelines provide recommendations for risk evaluation and laboratory investigation, a...
Source: Transplantation - January 31, 2018 Category: Transplant Surgery Tags: Reviews Source Type: research

Lucerne (Medicago sativa L.) in the human diet—Case reports and short reports
ConclusionsThis study presents a short review of the literature on the properties of lucerne and the secondary metabolites it contains and also on a protein concentrate produced from the lucerne juice. The case reports and short reports described in this review indicate that the lucerne protein concentrate can be used as a dietary supplement for improving the health and quality of human life.
Source: Journal of Herbal Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Variations in the quality of tuberculosis care in urban India: A cross-sectional, standardized patient study in two cities
by Ada Kwan, Benjamin Daniels, Vaibhav Saria, Srinath Satyanarayana, Ramnath Subbaraman, Andrew McDowell, Sofi Bergkvist, Ranendra K. Das, Veena Das, Jishnu Das, Madhukar Pai BackgroundIndia has the highest burden of tuberculosis (TB). Although most patients with TB in India seek care from the private sector, there is limited evidence on quality of TB care or its correlates. Following our validation study on the standardized patient (SP) method for TB, we utilized SPs to examine quality of adult TB care among health providers with different qualifications in 2 Indian cities. Methods and findingsDuring 2014 –2017, pilot p...
Source: PLoS Medicine - September 25, 2018 Category: Internal Medicine Authors: Ada Kwan Source Type: research

Fluoroquinolone resistant tuberculosis: A case report and literature review
Publication date: Available online 29 March 2019Source: Respiratory Medicine Case ReportsAuthor(s): Ajaypal Gill, Israel Ugalde, Christopher A. Febres-Aldana, Claudio TudaAbstractDespite the advancements made in medicine and treatment of tuberculosis over the last century, it remains a significant healthcare challenge. It remains the leading cause of death from a single infectious agent and the ninth leading cause of death worldwide. A 23-year-old male with a history of tuberculosis treated in Nepal seven years prior, presented to the emergency department with one week of hemoptysis, fever, chills, night sweats and weight ...
Source: Respiratory Medicine Case Reports - March 29, 2019 Category: Respiratory Medicine Source Type: research

Tuberculosis: a much-needed focus on transmission
Publication date: June 2019Source: The Lancet Respiratory Medicine, Volume 7, Issue 6Author(s): The Lancet Respiratory Medicine
Source: The Lancet Respiratory Medicine - May 22, 2019 Category: Respiratory Medicine Source Type: research

Earlier diagnosis and treatment assessment of tuberculosis achieved with pet/ct
(Society of Nuclear Medicine and Molecular Imaging) Research presented at the Society of Nuclear Medicine and Molecular Imaging's 2019 Annual Meeting shows that molecular imaging with 18F-FDG positron emission tomography/computed tomography (PET/CT) can evaluate tuberculosis at the molecular level, effectively identifying diseased areas and guiding treatment for patients.
Source: EurekAlert! - Medicine and Health - June 24, 2019 Category: International Medicine & Public Health Source Type: news

Medical students learn about practicing medicine with limited resources in Peru
Five UCLA medical students flew to Peru shortly before graduation to complete a clinical rotation at a hospital in Iquitos. Surrounded by the Amazon jungle, it ’s the world’s largest city that’s unreachable by road.After four years of working with the latest technology and state-of-the-art treatments, the students found their interaction with patients, who sometimes traveled weeks on the Amazon River by boat from remote villages,  a life-changing experience.Organized by theglobal health program in theDavid Geffen School of Medicine at UCLA, the three-week training, which was captured byNBC News, immersed the budding...
Source: UCLA Newsroom: Health Sciences - July 8, 2019 Category: Universities & Medical Training Source Type: news

What Does the Next 25 Years Hold for Global Health?
Source: Royal Society of Tropical Medicine and Hygiene (RSTMH). Published: 9/17/2019. This 30-page report is an analysis of survey data looking at 25 years of progress in and the future challenges for tropical medicine and global health. According to its findings, the biggest challenges to global health are the climate crisis; drug resistance, including antimicrobial resistance and multi-drug-resistant tuberculosis; and emerging epidemics. Mass migration, and the health and nutrition implications of climate-ravaged food supplies were also highlighted as major challenges to global health. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - September 17, 2019 Category: International Medicine & Public Health Source Type: news

Human Health Is in the Hands of Bacteria
In the beginning, there were single-cell bacteria. They were the only life on earth for billions of years, then larger cells evolved, then multicellular organisms, and then plants and animals. But the bacteria never went away, and all organisms, including us humans, have had to learn to live with them. Today, the lessons they are teaching us could change the trajectory of human health for generations. When bacteria were first discovered more than three centuries ago, most attention was on the ones we fought, which caused diseases like cholera, typhoid and tuberculosis. Through vaccines and antibiotics, we have made amazing...
Source: TIME: Health - October 24, 2019 Category: Consumer Health News Authors: Martin J. Blaser Tags: Uncategorized medicine Source Type: news

Xiao Chai Hu Tang, a herbal medicine, for chronic hepatitis B.
CONCLUSIONS: The clinical effects of Xiao Chai Hu Tang formula for chronic hepatitis B remain unclear. The included trials were small and of low methodological quality. Despite the wide use of Xiao Chai Hu Tang formula, we lack data on all-cause mortality, serious adverse events, health-related quality of life, hepatitis B-related mortality, and hepatitis B-related morbidity. The evidence in this systematic review comes from data obtained from a maximum three trials. We graded the certainty of evidence as very low for adverse events considered not to be serious and the surrogate outcomes HBeAg and HBV-DNA. We found a large...
Source: Cochrane Database of Systematic Reviews - November 6, 2019 Category: General Medicine Authors: Kong Z, Liang N, Yang GL, Zhang Z, Liu Y, Li J, Liu X, Liang S, Nikolova D, Jakobsen JC, Gluud C, Liu JP Tags: Cochrane Database Syst Rev Source Type: research

Recommendations Developed for Multidrug - Resistant Tuberculosis
Use of at least five drugs recommended for intensive - phase treatment, four drugs for continuation phase
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Family Medicine, Infections, Internal Medicine, Pathology, Pharmacy, Pulmonology, Surgery, Journal, Source Type: news

Serum proteins TGFBI, PCSK9, and CCL14 are potential biomarkers for different traditional Chinese medicine syndromes of multidrug-resistant tuberculosis.
Abstract Patients with multidrug-resistant tuberculosis (MDR-TB) tend to have a long course of anti-TB treatment and severe side effects. Traditional Chinese Medicine (TCM) has a synergistic effect in attenuation of MDR-TB. However, the lack of objective biological standards to classify and diagnose MDR-TB TCM syndromes could result in less effective TCM treatment. Therefore, in this study, we identified differentially expressed proteins (DEPs) in serum of individuals with MDR-TB TCM syndromes by applying isobaric tags for relative and absolute quantification coupled with two-dimensional liquid chromatography-tand...
Source: Anatomical Record - January 6, 2020 Category: Anatomy Authors: Hu YT, Yi WJ, Jiang TT, Tu HH, Wei LL, Shi LY, Liu CM, Chen J, Han YS, Gan L, Li ZB, Huang H, Li JC Tags: Anat Rec (Hoboken) Source Type: research