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Infectious Disease: Parasitic Diseases
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Total 6720 results found since Jan 2013.
Medical Misnomers are Murky: Time to Memorialize and Rename
Misnomers have dogged medical practice seemingly since its inception. They may arise out of initial misunderstanding of the underlying disease process, a fanciful personification of the disease itself, or simple confusion encountered early in the disease's discovery. Misnomers are not harmless. By increasing unneeded complexity, they add to challenges in medical education without increasing understanding. Practicing clinicians may experience difficulties in communicating with patients. For example, a diagnosis of “ringworm” may be made but the patient may not understand why an antiparasitic is not being prescribed, req...
Source: The American Journal of Medicine - September 22, 2023 Category: General Medicine Authors: Richie Manikat, Sanjiv Chopra Tags: Review Source Type: research
Antimalarial drug discovery against malaria parasites through haplopine modification: An advanced computational approach
J Cell Mol Med. 2023 Sep 19. doi: 10.1111/jcmm.17940. Online ahead of print.ABSTRACTThe widespread emergence of antimalarial drug resistance has created a major threat to public health. Malaria is a life-threatening infectious disease caused by Plasmodium spp., which includes Apicoplast DNA polymerase and Plasmodium falciparum cysteine protease falcipain-2. These components play a critical role in their life cycle and metabolic pathway, and are involved in the breakdown of erythrocyte hemoglobin in the host, making them promising targets for anti-malarial drug design. Our current study has been designed to explore the pote...
Source: Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Shopnil Akash Guendouzi Abdelkrim Imren Bayil Md Eram Hosen Nobendu Mukerjee Abdullah F Shater Fayez M Saleh Ghadeer M Albadrani Muath Q Al-Ghadi Mohamed M Abdel-Daim Tu ğba Taşkin Tok Source Type: research
The Frequency of Intestinal Parasitic Infections in COVID-19 Patients: A Case-Control Study in Tehran, Capital of Iran
In conclusion, more epidemiological and clinical research studies are needed to better understand the status and interaction of IPI in COVID-19 in Iran and other countries.PMID:37719419 | PMC:PMC10504051 | DOI:10.1155/2023/5359823
Source: Journal of Tropical Medicine - September 18, 2023 Category: Tropical Medicine Authors: Ali Taghipour Majid Pirestani Ramin Hamidi Farahani Mohammad Barati Source Type: research
Traditional uses, phytochemistry, pharmacology, and toxicology of the genus Artemisia L. (Asteraceae): A high-value medicinal plant
Curr Top Med Chem. 2023 Sep 14. doi: 10.2174/1568026623666230914104141. Online ahead of print.ABSTRACTBiologically active secondary metabolites, essential oils, and volatile compounds derived from medicinal and aromatic plants play a crucial role in promoting human health. Within the large family Asteraceae, the genus Artemisia consists of approximately 500 species. Artemisia species have a rich history in traditional medicine worldwide, offering remedies for a wide range of ailments, such as malaria, jaundice, toothache, gastrointestinal problems, wounds, inflammatory diseases, diarrhoea, menstrual pains, skin disorders, ...
Source: Current Topics in Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Manzoor Hussain Rakesh Kr Thakur Jabeena Khazir Sajad Ahmed Mohammad Imtiyaj Khan Praveen Rahi Latif Ahmad Peer V S Pragadheesh Satwinderjeet Kaur S N Raina Zafar Ahmad Reshi Deepmala Sehgal Vijay Rani Rajpal Bilal Ahmad Mir Source Type: research
A Novel Nested Multiplex Polymerase Chain Reaction Assay for Malaria Diagnosis Using the Hydroxymethyl Dihydropterin Pyrophosphokinase-Dihydropteroate Synthase (hppk-dhps) Gene
Am J Trop Med Hyg. 2023 Sep 11:tpmd230130. doi: 10.4269/ajtmh.23-0130. Online ahead of print.ABSTRACTThere are many techniques for malaria diagnosis. Currently, the nested polymerase chain reaction (PCR) method based on a small subunit ribosomal RNA gene (18S rRNA) has been used as a confirmatory method. However, this method is time-consuming, laborious, and costly. Therefore, the objective of this study was to develop nested multiplex PCR for Plasmodium species identification using the dihydropterin pyrophosphokinase-dihydropteroate synthase (hppk-dhps) gene. Genus- and species-specific primers for the hppk-dhps gene were...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Natpasit Chaianantakul Tippawan Sungkapong Kanokwan Nikhomkham Kansuda Sanseewong Sawanya Kornsang Source Type: research
Schistosoma mansoni-induced oxidative stress triggers hepatocellular proliferation
CONCLUSIONS: Our data suggest that hepatocellular proliferation is triggered by S. mansoni egg-induced oxidative stress.PMID:37696392 | DOI:10.1016/j.jcmgh.2023.08.014
Source: Molecular Medicine - September 11, 2023 Category: Molecular Biology Authors: Verena von B ülow Maryam Schneider Dorothee Dreizler Lena Russ Anne Baier Nicola Buss Jakob Lichtenberger Lukas H ärle Heike M üller Annette Tschuschner Gabriele Schramm J örn Pons-Kühnemann Christoph G Grevelding Elke Roeb Martin Roderfeld Source Type: research
A Novel Nested Multiplex Polymerase Chain Reaction Assay for Malaria Diagnosis Using the Hydroxymethyl Dihydropterin Pyrophosphokinase-Dihydropteroate Synthase (hppk-dhps) Gene
Am J Trop Med Hyg. 2023 Sep 11:tpmd230130. doi: 10.4269/ajtmh.23-0130. Online ahead of print.ABSTRACTThere are many techniques for malaria diagnosis. Currently, the nested polymerase chain reaction (PCR) method based on a small subunit ribosomal RNA gene (18S rRNA) has been used as a confirmatory method. However, this method is time-consuming, laborious, and costly. Therefore, the objective of this study was to develop nested multiplex PCR for Plasmodium species identification using the dihydropterin pyrophosphokinase-dihydropteroate synthase (hppk-dhps) gene. Genus- and species-specific primers for the hppk-dhps gene were...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Natpasit Chaianantakul Tippawan Sungkapong Kanokwan Nikhomkham Kansuda Sanseewong Sawanya Kornsang Source Type: research
