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Infectious Disease: Parasitic Diseases

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Total 6720 results found since Jan 2013.

Leprosy spreads by reprogramming nerve cells into migratory stem cells | Mo Costandi
The surprising modus operandi of a neglected tropical disease could lead to new stem cell therapiesThe bacterium that causes leprosy spreads through the body by converting nerve cells into stem cells with migratory properties, according to research published today in the journal Cell. The new findings could improve treatments for leprosy and other infectious diseases caused by bacteria, and help clinicians to diagnose them earlier. They may also provide a safe method for developing stem cell treatments for a wide variety of other conditions.Mycobacterium leprae is a parasitic bacterium that can only survive inside host cel...
Source: Guardian Unlimited Science - January 17, 2013 Category: Science Authors: Mo Costandi Tags: Health guardian.co.uk Neuroscience Editorial Medicine Source Type: news

A Case of Imported Severe Plasmodium falciparum Malaria in the Emergency Department and the Current Role of Exchange Transfusion Treatment
Conclusions: The high level of parasitemia presenting with acute kidney injury, hyperbilirubinemia, and thrombocytopenia supported the use of exchange transfusion as adjunct therapy. Exchange transfusion was a reasonable consideration in this case and was well tolerated by our patient. Institutions that are equipped with apheresis units should evaluate each case individually in concert with Centers for Disease Control experts and local consultants and weigh the risks and benefits of the use of exchange transfusion as an adjunct in the treatment of severe P. falciparum malaria.
Source: The Journal of Emergency Medicine - May 21, 2012 Category: Emergency Medicine Authors: Hania Habeeb, Jill R. Ripper, Alice Cohen, Patrick B. Hinfey Tags: Clinical Communications: Adults Source Type: research

Young malaria parasites refuse to take their medicine, may explain emerging drug resistance
(University of Melbourne) New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments for a disease that kills one person every minute and is developing resistance to drugs at an alarming rate.
Source: EurekAlert! - Medicine and Health - February 18, 2013 Category: Global & Universal Source Type: news

Artemisinin based combination therapy in travel medicine
Summary: A steadily increasing number of Western travellers are exposed to malaria. Also, numbers of migrants from malarious areas are increasing. Fast and effective treatment options are needed to ensure effective malaria treatment in these groups in the future. Artemisinin combinations are well tolerated and have shown high efficacy in malaria endemic areas. Since 2001, 42 malaria endemic countries, 23 of them in Africa, have adopted artemisinin based combination therapies recommended by WHO. An additional 14 countries are in the process of changing their malaria treatment policy. Studies in non-immune travellers confirm...
Source: Travel Medicine and Infectious Disease - February 27, 2013 Category: Infectious Diseases Authors: Tomas Jelinek Tags: Reviews Source Type: research

New malaria test kit gives a boost to elimination efforts worldwide
(London School of Hygiene & Tropical Medicine) A new, highly sensitive blood test that quickly detects even the lowest levels of malaria parasites in the body could make a dramatic difference in efforts to tackle the disease in the UK and across the world, according to new research.
Source: EurekAlert! - Medicine and Health - May 17, 2013 Category: Global & Universal Source Type: news

Antiprotozoal and antimycobacterial activities of Persea americana seeds
Background: Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites. Methods: The chloroformic and ethanolic extracts of P. americana seeds were prepared by maceration and their amoebicidal, giardicidal and trichomonicidal activity was evaluated. These extracts were also tested against Mycobacterium tuberculosis H37Rv, four mono-resistant and two multidrug resistant strains of M. tuberculosis as well as five non tuberculosis mycobacterium strains by MABA assay. Results: The chloroformic and etha...
Source: BMC Complementary and Alternative Medicine - May 16, 2013 Category: Complementary Medicine Authors: Adelina Jiménez-ArellanesJulieta Luna-HerreraRicardo Ruiz-NicolásJorge Cornejo-GarridoAmparo TapiaLilián Yépez-Mulia Source Type: research

East Africa: Long-Term Mass Drug Treatment Can Eliminate River Blindness - Study
[ASTMH]New research provides the first evidence in East Africa that long-term community-based drug treatment alone can interrupt transmission of onchocerciasis, a parasitic disease commonly known as river blindness. The study finds that after eight years (beginning in 1998) of treating residents annually with the anti-worming medicine ivermectin, followed by six years of semi-annual treatment with the drug, there is no evi
Source: AllAfrica News: Health and Medicine - May 21, 2013 Category: African Health Source Type: news

Mast cells fuel the fire of malaria immunopathology
Nature Medicine 19, 672 (2013). doi:10.1038/nm.3227 Authors: Christian R Engwerda & Rajiv Kumar Malaria remains the most deadly human parasitic disease. A new study finds that malaria parasites signal to mast cells to promote disease through the expansion of specialist dendritic cells and the subsequent activation of pathogenic CD8+ T cells (pages 730–738).
Source: Nature Medicine - June 6, 2013 Category: Journals (General) Authors: Christian R EngwerdaRajiv Kumar Tags: News and Views Source Type: research

Ivermectin Causes Cimex lectularius (Bedbug) Morbidity and Mortality
Conclusions: It may be possible that ivermectin could help eradicate, suppress, or prevent a bedbug infestation.
Source: The Journal of Emergency Medicine - July 22, 2013 Category: Emergency Medicine Authors: Johnathan M. Sheele, John F. Anderson, Thang D. Tran, Yu A. Teng, Peter A. Byers, Bhaskara S. Ravi, Daniel E. Sonenshine Tags: Public Health in Emergency Medicine Source Type: research

Clinical Update and Treatment of Selected Infectious Gastrointestinal Diseases in Avian Species
Abstract: The anatomy of the avian gastrointestinal (GI) tract is unique and significantly different from that of other animals. The characteristics of the avian GI tract allow the different species to adapt and thrive in their habitats. Infectious diseases of bacterial, viral, fungal, and parasitic origin commonly affect avian species. The significance and the nature of these pathologies vary with species and if they live in the wild or a captive environment. This review compiles information available in the literature on specific infectious processes that were considered relevant and clinically significant by the authors...
Source: Journal of Exotic Pet Medicine - April 1, 2013 Category: Veterinary Research Authors: João Brandão, Hugues Beaufrère Tags: Topics in Medicine and Surgery Source Type: research

Ivermectin Causes Cimex lectularius (Bedbug) Morbidity and Mortality
Conclusions: It may be possible that ivermectin could help eradicate, suppress, or prevent a bedbug infestation.
Source: The Journal of Emergency Medicine - July 22, 2013 Category: Emergency Medicine Authors: Johnathan M. Sheele, John F. Anderson, Thang D. Tran, Yu A. Teng, Peter A. Byers, Bhaskara S. Ravi, Daniel E. Sonenshine Tags: Public Health in Emergency Medicine Source Type: research

Has the Guinea worm been eradicated?
Donald Hopkins, M.D., vice president for health programs at the Carter Center, helped eradicate smallpox. Now he is close to eliminating the ancient Guinea worm, a parasitic infection that is spread by drinking water contaminated with water fleas. The parasites mature in the abdomen and work their way to the surface after a year. The worms create painful lesions that release hundreds of thousands ....
Source: Sound Medicine - September 29, 2013 Category: Global & Universal Authors: Sound Medicine Source Type: news

In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi
Conclusion: These results indicate that the 7-hydroxycalamenene-rich essential oil from C. cajucara is a promising source of leishmanicidal compounds.
Source: BMC Complementary and Alternative Medicine - October 2, 2013 Category: Complementary Medicine Authors: Igor RodriguesMariana AzevedoFrancisco ChavesHumberto BizzoSuzana Corte-RealDaniela AlvianoCeluta AlvianoMaria RosaAlane Vermelho Source Type: research

Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review
Conclusions: The available in-vitro and in-vivo evidence suggests that CZ has many beneficial health effects. However, since data on humans are sparse, randomized controlled trials in humans will be necessary to determine whether these effects have public health implications.
Source: BMC Complementary and Alternative Medicine - October 22, 2013 Category: Complementary Medicine Authors: Priyanga RanasingheShehani PigeraGA PremakumaraPriyadarshani GalappaththyGodwin ConstantinePrasad Katulanda Source Type: research