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< em > Sigesbeckia orientalis < /em > Extract Ameliorates the Experimental Diabetic Nephropathy by Downregulating the Inflammatory and Oxidative Stress Signaling Pathways
Evid Based Complement Alternat Med. 2022 Aug 5;2022:3323745. doi: 10.1155/2022/3323745. eCollection 2022.ABSTRACTDiabetes in children and its complications are on the rise globally, which is accompanied by increasing in diabetes-related complications. Oxidative stress and inflammation induced by elevated blood sugar in diabetic patients are considered risk factors associated with the development of diabetes complications, including chronic kidney disease and its later development to end-stage renal disease. Microvascular changes within the kidneys of DM patients often lead to chronic kidney disease, which aggravates the il...
Source: Evidence-based Complementary and Alternative Medicine - August 15, 2022 Category: Complementary Medicine Authors: Chung-Ming Chen Jer-Yiing Houng Tsui-Ling Ko Shu-Hui Juan Hsiu-Chu Chou Source Type: research
Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway
CONCLUSION: DN golden hamster kidney NLRP3-Caspase-1-GSDMD signalling was enhanced. BBR can reduce oxidative stress damage by regulating antioxidative Nrf2 and then regulating NLRP3-Caspase-1-GSDMD signalling to inhibit pyroptosis, antagonizing DN inflammation-induced damage.PMID:35971382 | PMC:PMC9375700 | DOI:10.1155/2021/5545193
Source: Evidence-based Complementary and Alternative Medicine - August 16, 2022 Category: Complementary Medicine Authors: Baozhu Ding Songyan Geng Xiaojie Hou Xuelian Ma Huazhou Xu Fan Yang Kun Liu Wenjie Liang Guoping Ma Source Type: research
Olfactory marker protein regulation of glucagon secretion in hyperglycemia
Experimental & Molecular Medicine, Published online: 14 September 2022; doi:10.1038/s12276-022-00843-8The same signaling pathway that controls smell perception in the nose is involved in regulating the release of a pancreatic hormone needed when blood sugar levels are high. The olfactory marker protein (OMP) is a marker of chemical signaling mediated by olfactory receptors, which are located not only in the nose but throughout the body. A research team led by Eun Jig Lee and Yoon Hee Cho from Yonsei University College of Medicine, Seoul, South Korea, showed that human and mouse pancreatic α-cells, endocrine cells that...
Source: Experimental and Molecular Medicine - September 14, 2022 Category: Molecular Biology Authors: Ju Hun Oh Ye Eon Han Ya Ru Bao Chan Woo Kang JaeHyung Koo Cheol Ryong Ku Yoon Hee Cho Eun Jig Lee Source Type: research
Hospital Closures Pose Challenges to Care
Empty beds in a hospital room.
When 10-bed Nye Regional Medical Center, in west-central Nevada, closed abruptly in 2015, it meant that the residents of the former gold-mining town of Tonopah would have to drive about two hours across a hundred miles of desert roads to get to the nearest hospital.
The hospital’s CEO, Wayne Allen, didn’t sugar-coat it.
“This is a decision that will ultimately jeopardize the health and well-being of our community and surrounding areas,” he said.
Hospital closures over the last decade—most notably in rural areas and in pediatrics, but urban closures as well—have left patients wi...
Source: The Hospitalist - November 1, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Business of Medicine Career Pediatrics PHM22 Source Type: research
Has anyone tried Plexus for Blood Sugar control?
Hi y'all! I am 32 yo female and found out last June my A1C was elevated. Rather than jump right into insulin, I decided to do my best to control by being careful about the foods I eat. I was having some success (when I was perfect) but now I'm pregnant! With pregnancies 1 and 2 this meant sugars that went a little crazy. My friend sells Plexus products (they have a full selection of supplements, probiotics, etc) and a specific product called Plexus Slim. Anyone heard of it? Well, don't let the name fool you. It was developed for blood sugar regulation and then they discovered some people lost weight on it (because of BS re...
Source: Cystic Fibrosis Alternative Medicine Forum - March 15, 2015 Category: Respiratory Medicine Authors: jmiller1 Tags: Alternative Medicine Source Type: forums
Crystallizing sugar science
Nature Medicine 22, 1369 (2016).
doi:10.1038/nm.4250
Recent ballot initiatives instituting a tax on sugary drinks in the US, alongside related efforts by other countries and support from the World Health Organization, bring to the forefront the need for greater scientific insight into how sugars affect metabolic health.
Source: Nature Medicine - December 5, 2016 Category: Journals (General) Tags: Editorial Source Type: research
Sugar Intake During Pregnancy Tied to Allergy in Offspring
As maternal sugar intake rose, so did allergies and asthma in children by age 7
Source: Pulmonary Medicine News - Doctors Lounge - July 7, 2017 Category: Respiratory Medicine Tags: Family Medicine, Gynecology, Nursing, Pathology, Pediatrics, Pulmonology, Allergy, Journal, Source Type: news
Diabetes complications are a risk factor for repeat hospitalizations, study shows
(Mayo Clinic) For patients with diabetes, one reason for hospitalization and unplanned hospital readmission is severe dysglycemia (uncontrolled hyperglycemia -- high blood sugar, or hypoglycemia -- low blood sugar), says new research published in the Journal of General Internal Medicine.
Source: EurekAlert! - Medicine and Health - July 7, 2017 Category: International Medicine & Public Health Source Type: news
A School-Based Brand Marketing Program ’s Adherence to Federal Nutrition Criteria
Conclusions Fewer than one third of Box Tops foods met the Smart Snacks standards. Schools should consider whether the benefit of participation outweighs the harm of exposing kids to unhealthful marketing. Alternatively, schools could opt not to participate unless companies limit redeemable products to household items or healthful options meeting the Smart Snacks standards.
Source: American Journal of Preventive Medicine - August 16, 2017 Category: International Medicine & Public Health Source Type: research
The Benefits and Risks of Energy Drinks in Young Adults and Military Service Members.
CONCLUSION: The needs assessment points to a desire for more ED knowledge of health providers working with TBI patients. A few key themes emerged from the exploratory literature review that can be taken into consideration when educating health providers and delivering knowledge-based resources. Adverse effects of EDs are most closely associated with the dose of caffeine consumed. In general, the combination of ED with alcohol should be avoided because the ED can mask the level of intoxication, and the combination may be associated with increased risk-taking behavior. Overall, the risks and benefits of EDs remain controvers...
Source: Military Medicine - August 17, 2017 Category: International Medicine & Public Health Tags: Mil Med Source Type: research
Prevalence of Modifiable Cancer Risk Factors Among U.S. Adults Aged 18 –44 Years
Conclusions Findings can be used to target evidence-based environmental and policy interventions to reduce the prevalence of cancer risk factors among young adults and prevent the development of future cancers.
Source: American Journal of Preventive Medicine - August 17, 2017 Category: International Medicine & Public Health Source Type: research
UMass Amherst study of bee health finds no natural medicine in once-promising compound
(University of Massachusetts at Amherst) Ph.D. student Evan Palmer-Young and advisor evolutionary ecologist Lynn Adler had reported in 2015 that a parasitic infection of bumble bees, Crithidia bombi, was reduced when the bees fed on anabasine, a natural alkaloid, in sugar water. They had hoped their finding was evidence that bees may use 'nature's medicine cabinet' to rid themselves of the intestinal parasite. But they report in the current issue of PLOS ONE that result was not repeated.
Source: EurekAlert! - Biology - August 28, 2017 Category: Biology Source Type: news
The Potential for Federal Preemption of State and Local Sugar-Sweetened Beverage Taxes
Publication date: Available online 29 August 2017 Source:American Journal of Preventive Medicine Author(s): Jennifer L. Pomeranz, Dariush Mozaffarian, Renata Micha
Source: American Journal of Preventive Medicine - August 29, 2017 Category: International Medicine & Public Health Source Type: research
More evidence: Untreated sleep apnea shown to raise metabolic and cardiovascular stress
(Johns Hopkins Medicine) Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects. A report of the study's findings, published in the August issue of The Journal of Clinical Endocrinology& Metabolism, adds further support for the consistent use of continuous positive airway pressure (CPAP), a machine that increases air pressure in the throat to keep the airway open during sleep.
Source: EurekAlert! - Medicine and Health - August 31, 2017 Category: International Medicine & Public Health Source Type: news
Employment changes associated with the introduction of taxes on sugar-sweetened beverages and nonessential energy-dense food in Mexico
In conclusion, there were no employment reductions associated with the fiscal policies implemented in Mexico in 2014 on SSB and nonessential energy-dense food.
Source: Preventive Medicine - September 8, 2017 Category: International Medicine & Public Health Source Type: research
