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Total 22 results found since Jan 2013.

Bilateral Panuveitis Mimicking Vogt-Koyanagi-Harada Disease following the First Dose of ChAdOx1 nCoV-19 Vaccine
CONCLUSIONS: Bilateral panuveitis mimicking Vogt-Koyanagi-Harada disease can develop shortly after the first dose of the ChAdOx1 nCoV-19 vaccine. Ophthalmologists should consider bilateral panuveitis as a presumed post-vaccination adverse event. Systemic steroid therapy may be effective for the nCoV-19 vaccine-associated panuveitis.PMID:35113750 | DOI:10.1080/09273948.2022.2026410
Source: Ocular Immunology and Inflammation - February 3, 2022 Category: Allergy & Immunology Authors: Sang Yoon Kim Min Seung Kang Han Jo Kwon Source Type: research

Neuro-ophthalmological evaluation including optical coherence tomography surrounding venous sinus stenting in idiopathic intracranial hypertension with papilledema: a case series
This study demonstrat es that neuro-ophthalmologic testing augmented with OCT evaluation provides objective data that can be used as a biomarker for treatment success for managing patients with different extents of papilledema and may inform patient management.
Source: Neurosurgical Review - January 24, 2022 Category: Neurosurgery Source Type: research

Vogt-Koyanagi-Harada Disease Following COVID-19 Infection
We present a case of incomplete Vogt-Koyanagi-Harada disease following COVID-19 infection.Case Rep Ophthalmol 2021;12:804 –808
Source: Case Reports in Ophthalmology - September 21, 2021 Category: Opthalmology Source Type: research

An Evaluation of the Relationship between Retinal Nerve Fiber Thickness, Cochlear Nerve Thickness, the Level of Tinnitus, and Hearing Loss in Unilateral Tinnitus Patients
Conclusion: The study results clearly showed a relationship between cochlear nerve fiber thickness and hearing loss and the severity of tinnitus in cases with unilateral tinnitus and that there could be neurodegenerative factors in the disease etiology. A similar relationship seen with the RNFL supports the study hypothesis.Audiol Neurotol
Source: Audiology and Neurotology - February 24, 2021 Category: Audiology Source Type: research

Why Do We Dream? A New Theory on How It Protects Our Brains
When he was two years old, Ben stopped seeing out of his left eye. His mother took him to the doctor and soon discovered he had retinal cancer in both eyes. After chemotherapy and radiation failed, surgeons removed both his eyes. For Ben, vision was gone forever. But by the time he was seven years old, he had devised a technique for decoding the world around him: he clicked with his mouth and listened for the returning echoes. This method enabled Ben to determine the locations of open doorways, people, parked cars, garbage cans, and so on. He was echolocating: bouncing his sound waves off objects in the environment and cat...
Source: TIME: Science - December 29, 2020 Category: Science Authors: David Eagleman and Don Vaughn Tags: Uncategorized Source Type: news

Vestibular function assessment of Susac syndrome patients by the video head impulse test and cervical vestibular-evoked myogenic potentials.
CONCLUSIONS: This is the first study to describe the results of the vHIT and cVEMPs among a group of patients with SuS. The results suggest that the vHIT should not be the only exam used to assess the function of the vestibular system of SuS patients. PMID: 33337398 [PubMed - as supplied by publisher]
Source: Journal of Vestibular Research: Equilibrium and Orientation - December 19, 2020 Category: Neuroscience Tags: J Vestib Res Source Type: research

Vasculat treatment concepts in glaucoma patients.
CONCLUSION: Besides optimizing systemic blood pressure, reducing an increased central retinal venous pressure, treatment with statins, calcium channel blockers, Ginkgo biloba extract, increased physical exercise and fluid replacement are options to ameliorate vascular conditions. An interdisciplinary cooperation with general practitioners and internists is an important component of holistic treatment. PMID: 33026527 [PubMed - as supplied by publisher]
Source: Der Ophthalmologe - October 7, 2020 Category: Opthalmology Authors: Pillunat KR, Pillunat LE Tags: Ophthalmologe Source Type: research

Demographics, Clinical Characteristics, and Management of Idiopathic Intracranial Hypertension in Kuwait: A Single-Center Experience
Conclusion: Incidence of IIH in Kuwait is similar to other regional studies but higher than Western studies. Demographics and clinical features of IIH in our study are comparable to international and regional figures. Most of our patients had a benign course. IIH is more prevalent in females and strongly associated with obesity.
Source: Frontiers in Neurology - August 10, 2020 Category: Neurology Source Type: research

Rituximab in the treatment of Susac's syndrome: Report of a case.
CONCLUSION: A standard treatment paradigm is lacking in Susac's syndrome as randomized controlled trials do not exist. There are no definitive scores to predict its outcome, and early diagnosis is important as the organs involved can easily become irreversibly damaged. Thus, patients with Susac's syndrome must be treated promptly and aggressively. Our report highlights the possibility of positive long-term prognosis with an early use of rituximab. However, a systematic therapeutic approach on the basis of controlled trials is mandatory to develop a consensus. PMID: 32380850 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - May 6, 2020 Category: Opthalmology Authors: Monferrer-Adsuara C, Remolí-Sargues L, Hernández-Bel L, Gracia-García A, Hernández-Garfella ML, Cervera-Taulet E Tags: Eur J Ophthalmol Source Type: research

Drug-Induced Intracranial Hypertension: A Systematic Review and Critical Assessment of Drug-Induced Causes
ConclusionWe suggest using the term ‘drug-induced intracranial hypertension’ (DIIH) and propose a set of diagnostic criteria for DIIH. Our review attempts to identify DIIH-associated drugs based on a strict diagnostic and drug-causality algorithm, then stratify them into appropriate risks categories. This may ultimately assist phy sicians in counselling patients about the risk of DIIH when prescribing medications and recognizing this uncommon yet sight-threatening condition.
Source: American Journal of Clinical Dermatology - November 17, 2019 Category: Dermatology Source Type: research

Vogt-Koyanagi-Harada-like Disease following Yellow Fever Vaccination.
Conclusion: Yellow fever vaccine may be a possible trigger for VKH. PMID: 31603703 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - October 12, 2019 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors
AbstractBalancing the potential for durable remissions with autoimmune-like toxicities is a key clinical challenge in the use of immune checkpoint inhibitors (ICI). Certain toxicities are associated with an increased response rate; however, the molecular underpinnings of this association are poorly understood. Here, we report a patient with wide spread uveal melanoma who had an exceptional response to treatment with ipilimumab and nivolumab, but suffered severe immune-related sequelae, including central serous retinopathy with retinal detachment, tinnitus, and vitiligo resembling Vogt-Koyanagi-Harada disease, and refractor...
Source: Journal for Immunotherapy of Cancer - March 3, 2019 Category: Cancer & Oncology Source Type: research