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Total 4168 results found since Jan 2013.
A Review on the Antimutagenic and Anticancer Effects of Cysteamine
In conclusion, regarding the high safety profile of cysteamine and the current literature data presented in this article, cysteamine might be considered as an interesting molecule for the prevention and the treatment of cancer. Further clinical studies should be performed to support these data in humans.PMID:37731680 | PMC:PMC10508993 | DOI:10.1155/2023/2419444
Source: Adv Data - September 21, 2023 Category: Epidemiology Authors: Chun-Man Lee Source Type: research
Proteome-wide mendelian randomization study implicates therapeutic targets in common cancers
The interest in targeted cancer therapies has been growing rapidly. While numerous cancer biomarkers and targeted treatment strategies have been developed and employed, there are still significant limitations ...
Source: Journal of Translational Medicine - September 21, 2023 Category: Research Authors: Feihong Ren, Qiubai Jin, Tongtong Liu, Xuelei Ren and Yongli Zhan Tags: Research Source Type: research
Insight of novel biomarkers for papillary thyroid carcinoma through multiomics
DiscussionMultiomics analysis of the Chinese cohort demonstrated significant distinctions compared to TCGA-THCA cohorts, highlighting the unique genetic characteristics of Chinese individuals with PTC. The novel biomarkers, holding potential for diagnosis and prognosis of PTC, were identified. Furthermore, these biomarkers provide a valuable tool for precise medicine, especially for immunotherapeutic or nanomedicine based cancer therapy.
Source: Frontiers in Oncology - September 19, 2023 Category: Cancer & Oncology Source Type: research
Peroxisome proliferator-activated receptors as therapeutic target for cancer
J Cell Mol Med. 2023 Sep 12. doi: 10.1111/jcmm.17931. Online ahead of print.ABSTRACTPeroxisome proliferator-activated receptors (PPARs) are transcription factors belonging to the nuclear receptor family. There are three subtypes of PPARs, including PPAR-α, PPAR-β/δ and PPAR-γ. They are expressed in different tissues and act by regulating the expression of target genes in the form of binding to ligands. Various subtypes of PPAR have been shown to have significant roles in a wide range of biological processes including lipid metabolism, body energy homeostasis, cell proliferation and differentiation, bone formation, tiss...
Source: Molecular Medicine - September 13, 2023 Category: Molecular Biology Authors: Yuqing Wang Feifei Lei Yiyun Lin Yuru Han Lei Yang Huabing Tan Source Type: research
Comparison and Incorporation of Reasoning and Learning Approaches for Cancer Therapy Research
Stud Health Technol Inform. 2023 Sep 12;307:161-171. doi: 10.3233/SHTI230709.ABSTRACTRepresenting knowledge in a comprehensible and maintainable way and transparently providing inferences thereof are important issues, especially in the context of applications related to artificial intelligence in medicine. This becomes even more obvious if the knowledge is dynamically growing and changing and when machine learning techniques are being involved. In this paper, we present an approach for representing knowledge about cancer therapies collected over two decades at St.-Johannes-Hospital in Dortmund, Germany. The presented appro...
Source: Studies in Health Technology and Informatics - September 12, 2023 Category: Information Technology Authors: Andre Thevapalan Daan Apeldoorn Gabriele Kern-Isberner Ralf G Meyer Mathias Nietzke Torsten Panholzer Source Type: research
Therapeutic effects of medicinal plants and their constituents on lung cancer, in vitro, in vivo and clinical evidence
J Cell Mol Med. 2023 Sep 12. doi: 10.1111/jcmm.17936. Online ahead of print.ABSTRACTThe most common type of cancer in the world is lung cancer. Traditional treatments have an important role in cancer therapy. In the present review, the most recent findings on the effects of medicinal plants and their constituents or natural products (NP) in treating lung cancer are discussed. Empirical studies until the end of March 2022 were searched using the appropriate keywords through the databases PubMed, Science Direct and Scopus. The extracts and essential oils tested were all shown to effect lung cancer by several mechanisms inclu...
Source: Molecular Medicine - September 12, 2023 Category: Molecular Biology Authors: Arghavan Memarzia Saeideh Saadat Fereshteh Asgharzadeh Sepide Behrouz Gert Folkerts Mohammad Hossein Boskabady Source Type: research
Comparison and Incorporation of Reasoning and Learning Approaches for Cancer Therapy Research
Stud Health Technol Inform. 2023 Sep 12;307:161-171. doi: 10.3233/SHTI230709.ABSTRACTRepresenting knowledge in a comprehensible and maintainable way and transparently providing inferences thereof are important issues, especially in the context of applications related to artificial intelligence in medicine. This becomes even more obvious if the knowledge is dynamically growing and changing and when machine learning techniques are being involved. In this paper, we present an approach for representing knowledge about cancer therapies collected over two decades at St.-Johannes-Hospital in Dortmund, Germany. The presented appro...
Source: Studies in Health Technology and Informatics - September 12, 2023 Category: Information Technology Authors: Andre Thevapalan Daan Apeldoorn Gabriele Kern-Isberner Ralf G Meyer Mathias Nietzke Torsten Panholzer Source Type: research
Therapeutic effects of medicinal plants and their constituents on lung cancer, in vitro, in vivo and clinical evidence
J Cell Mol Med. 2023 Sep 12. doi: 10.1111/jcmm.17936. Online ahead of print.ABSTRACTThe most common type of cancer in the world is lung cancer. Traditional treatments have an important role in cancer therapy. In the present review, the most recent findings on the effects of medicinal plants and their constituents or natural products (NP) in treating lung cancer are discussed. Empirical studies until the end of March 2022 were searched using the appropriate keywords through the databases PubMed, Science Direct and Scopus. The extracts and essential oils tested were all shown to effect lung cancer by several mechanisms inclu...
Source: Molecular Medicine - September 12, 2023 Category: Molecular Biology Authors: Arghavan Memarzia Saeideh Saadat Fereshteh Asgharzadeh Sepide Behrouz Gert Folkerts Mohammad Hossein Boskabady Source Type: research
Comparison and Incorporation of Reasoning and Learning Approaches for Cancer Therapy Research
Stud Health Technol Inform. 2023 Sep 12;307:161-171. doi: 10.3233/SHTI230709.ABSTRACTRepresenting knowledge in a comprehensible and maintainable way and transparently providing inferences thereof are important issues, especially in the context of applications related to artificial intelligence in medicine. This becomes even more obvious if the knowledge is dynamically growing and changing and when machine learning techniques are being involved. In this paper, we present an approach for representing knowledge about cancer therapies collected over two decades at St.-Johannes-Hospital in Dortmund, Germany. The presented appro...
Source: Studies in Health Technology and Informatics - September 12, 2023 Category: Information Technology Authors: Andre Thevapalan Daan Apeldoorn Gabriele Kern-Isberner Ralf G Meyer Mathias Nietzke Torsten Panholzer Source Type: research
