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Total 26176 results found since Jan 2013.
Gonioscopy and Angle-Based Glaucoma Surgical Training on Human Eyes in the Wet Lab
Précis:
Human corneoscleral rims provide a low cost model and resource to enhance angle based glaucoma surgical training skills.
Purpose:
To understand the feasibility, utility, and efficacy of a low-cost model for performing anterior chamber angle gonioscopy and micro-surgery on human corneoscleral tissues in wet lab on resident skill enhancement.
Methods:
Post-keratoplasty residual corneoscleral rims and/or the expired donor corneoscleral buttons were included for the purpose of this study. Initially, inverted rims were used to demonstrate the basic angle anatomy on a slit lamp bio-microscope. Central ...
Source: Journal of Glaucoma - October 1, 2022 Category: Opthalmology Tags: Novel Glaucoma Insights: Original Studies Source Type: research
Patterns of Optical Coherence Tomography Imaging in Preperimetric Open Angle Glaucoma: A Comparative Study With Young-Age-Onset and Old-Age-Onset Eyes
Précis:
Optic coherence tomography imaging in preperimetric open angle glaucoma (OAG) differed between young-age-onset and old-age-onset eyes. Inferior and superior quadrants were thinner in young and old-age-onset eyes, respectively. Understanding the specific patterns of early glaucomatous damage based on age-at-onset may improve glaucoma diagnosis and monitoring.
Purpose:
To investigate the patterns of retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GCIPL) thinning in preperimetric OAG by optical coherence tomography based on age at onset (“young-age onset (
Source: Journal of Glaucoma - November 1, 2022 Category: Opthalmology Tags: New Understandings of Glaucoma: Original Studies Source Type: research
Diurnal Variation of Corneal Hysteresis in Patients With Untreated Primary Open Angle Glaucoma and Normal Individuals
Précis:
Corneal hysteresis in both patients with untreated open angle glaucoma and normal individuals demonstrated significant diurnal variation independent of confounding factors and was higher in the nighttime than in the daytime.
Purpose:
To investigate diurnal variations in corneal hysteresis (CH) in patients with untreated primary open angle glaucoma (POAG) and normal individuals by using an ocular response analyzer.
Materials and Methods:
This prospective study included 72 eyes of 53 patients with untreated POAG and 53 eyes of 47 normal individuals. Intraocular pressure (IOP) and CH were measured u...
Source: Journal of Glaucoma - November 1, 2022 Category: Opthalmology Tags: New Understandings of Glaucoma: Original Studies Source Type: research
Risk Factors for Trabeculotomy Failure in Primary Congenital Glaucoma
Conclusions:
A higher baseline IOP, younger age, larger corneal diameter, and bilaterality were identified as risk factors for trabeculotomy failure in congenital glaucoma. The presence of one or more of these should be considered in the decision-making process when considering surgical options to manage glaucoma in these patients.
Source: Journal of Glaucoma - December 1, 2022 Category: Opthalmology Tags: Novel Glaucoma Insights: Original Studies Source Type: research
The Effect of Latanoprost on Choroidal Vascularity Index in Glaucoma and Ocular Hypertension
Précis:
The choroidal vascularity index (CVI) is a new marker for the choroid. The decrease in CVI following latanoprost use can provide a better understanding of the pathogenesis of the posterior segment side effects of latanoprost such as cystoid macular edema and central serous choroidopathy.
Purpose:
The purpose of this paper is to evaluate the changes in the CVI, total choroidal area (TCA), stromal area (SA), luminal area (LA), and choroidal thickness (CT) following latanoprost therapy in patients with primary open angle glaucoma and ocular hypertension.
Materials and Methods:
Patients with newly di...
Source: Journal of Glaucoma - December 1, 2022 Category: Opthalmology Tags: Novel Glaucoma Insights: Original Studies Source Type: research
Rate of Corneal Grafting Post-Glaucoma Drainage Device Use in Pediatric and Adult Patients
Précis:
Kaplan-Meier analysis was used to compare the rate of corneal grafting after glaucoma drainage device (GDD) placement in pediatric and adult patients. Adults were at an increased risk of receiving a corneal graft after device placement.
Purpose:
The goal of this study was to compare the rate of corneal graft implantation after GDD placement in pediatric and adult patients.
Patients:
Patients receiving a GDD between January 1, 1985 and December 31, 2017 were selected from the medical records. Patients receiving their first device while
Source: Journal of Glaucoma - April 1, 2021 Category: Opthalmology Tags: Glaucoma Surgery: Original Studies Source Type: research
Long-term Outcome of Ahmed Glaucoma Valve Implantation in Eyes With Intractably Raised Intraocular Pressure Following Pars Plana Vitrectomy
Precis:
Ahmed glaucoma valve (AGV) implantation led to a significant reduction in intraocular pressure (IOP) and in antiglaucoma medications in vitrectomized eyes in previously nonglaucomatous eyes. The most common indication for vitrectomy was ocular trauma-related complications.
Purpose:
The purpose of this study was to report the long-term outcomes of AGV implantation in patients of uncontrolled IOP after pars plana vitrectomy (PPV).
Materials and Methods:
Medical records of patients (age 18 y and above) who underwent AGV implantation between January 2006 and December 2017 for uncontrolled IOP follow...
Source: Journal of Glaucoma - April 1, 2021 Category: Opthalmology Tags: Glaucoma Surgery: Original Studies Source Type: research
Semiautomated Assessment of Anterior Segment Structures in Pediatric Glaucoma Using Quantitative Ultrasound Biomicroscopy
The study was a prospective observational study comparing semiautomated to manual quantitative ultrasound biomicroscopy image analysis among 82 images from 41 eyes of 32 subjects (21 controls and 11 glaucoma) enrolled in the Pediatric Anterior Segment Imaging Innovation Study. Intraclass correlation coefficients and correlation coefficients were>0.8 for all parameters, and comparison of respective analysis speed was 7 times faster for the semiautomated method compared with manual image quantification.
Source: Journal of Glaucoma - April 30, 2021 Category: Opthalmology Tags: Glaucoma Assessment: Original Studies Source Type: research
Comparison of Tono-Pen Avia and Handheld Applanation Tonometry in Primary Congenital Glaucoma
Précis:
Tono-Pen AVIA (TPA) intraocular pressure (IOP) values are different from those taken with handheld Goldmann applanation tonometer (GAT) in primary congenital glaucoma (PCG). These differences indicate both tonometers cannot be used interchangeably for measuring IOP in PCG.
Purpose:
The aim was to compare IOP measurements obtained using TPA and a handheld version of GAT in children with PCG.
Materials and Methods:
Forty-two eyes from 23 patients were evaluated for central corneal thickness (CCT), axial length, biomicroscopy and IOP measurement with TPA and a handheld GAT under inhalation anesthesi...
Source: Journal of Glaucoma - April 30, 2021 Category: Opthalmology Tags: Glaucoma Assessment: Original Studies Source Type: research
Corneal Properties in Primary Open-angle Glaucoma Assessed Through Scheimpflug Corneal Topography and Densitometry
Purpose:
The purpose of this study was to compare corneal topography and densitometry measurements in patients with primary open-angle glaucoma (POAG) and healthy subjects.
Patients and Methods:
A total of 200 eyes of 75 patients with POAG and 125 healthy controls underwent corneal topography and densitometry (Oculus Pentacam HR). The data compared in the 2 groups were: anterior chamber angle, anterior chamber depth, and anterior chamber volume, keratometry (Kminimum, Kmaximum, and Kmean), central corneal thickness, central anterior elevation, anterior elevation apex, maximum anterior elevation, and posterior el...
Source: Journal of Glaucoma - April 30, 2021 Category: Opthalmology Tags: The Cornea in Glaucoma: Original Studies Source Type: research
Bilateral Ocular Ischemic Syndrome in the Setting of Chronic Angle Closure Glaucoma
We report novel case of a 57-year-old woman who developed bilateral ocular ischemic syndrome in the setting of chronic angle closure glaucoma without associated angle neovascularization. Detailed is a course in which markedly prolonged, elevated intraocular pressure led to significantly reduced arterial perfusion at the level of the central retinal artery, leading to the clinical picture of ocular ischemic syndrome.
Source: Journal of Glaucoma - April 30, 2021 Category: Opthalmology Tags: Angle Closure Glaucoma Related: Case Reports Source Type: research
A Randomized Phase 2 Trial Comparing Omidenepag Isopropyl 0.002% Once and Twice Daily in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (SPECTRUM-6)
Conclusion:
In this study, the benefit-risk profile of omidenepag isopropyl 0.002% QD was more favorable than the benefit-risk profile of BID. This difference was driven by a higher incidence of local tolerability issues in the BID arm.
Source: Journal of Glaucoma - June 1, 2021 Category: Opthalmology Tags: Medical and Surgical Glaucoma: Original Studies Source Type: research
Comparing the Safety and Efficacy of Phacogoniosynechialysis With Phacotrabeculectomy in the Management of Refractory Acute Primary Closure Angle Glaucoma With Cataract: A Multicenter Randomized Trial
Précis:
Combined phacoemulsification-goniosynechialysis (phaco-GSL) and unaugmented phacotrabeculectomy were both found to be effective in treating eyes with significant cataract and medically unresponsive acute primary angle closure glaucoma (PACG). Phaco-GSL seemed to be safer, with fewer surgical complications, and achieved better visual acuity than phacotrabeculectomy.
Objectives:
To compare the results of combined phaco-GSL with unaugmented phacotrabeculectomy in the management of eyes with medically unresponsive acute PACG and cataract.
Participants and Research Methods:
This was a prospective rand...
Source: Journal of Glaucoma - July 1, 2021 Category: Opthalmology Tags: Advances in Glaucoma Surgery: Original Studies Source Type: research
Surgical Results of Ahmed Glaucoma Valve Implantation in One-chamber Eyes
Precis:
Ahmed glaucoma valve (AGV) implantation in eyes with damaged iris-lens diaphragms (“1-chamber” eyes) resulted in mean intraocular pressure (IOP) and antiglaucoma medications decreases of 66% and 59% (P
Source: Journal of Glaucoma - July 1, 2021 Category: Opthalmology Tags: Advances in Glaucoma Surgery: Original Studies Source Type: research
The Profile of Secondary Glaucoma in China: A Study of Over 10,000 Patients
This study analyzed the current profile of admitted patients with SG at the largest ophthalmic center in China.
Methods:
SG cases were retrieved retrospectively by International Classification of Disease-10 clinical coding data from January 2010 to December 2019. Demographic data, etiologies, and the management of SG were analyzed. The ratios of the etiologies were compared with previously reported data from other regions. The etiologies and management between the 2010 to 2014 group and the 2015 to 2019 group were compared.
Results:
A total of 11,730 cases were enrolled. The mean age of the patients with SG w...
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research
