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Pulmonary Scintigraphy for the Diagnosis of Acute Pulmonary Embolism: A Survey of Current Practices in Australia, Canada, and France
Conclusion: In the 3 countries surveyed, SPECT has largely replaced planar imaging for evaluation of PE, with almost half of the SPECT studies incorporating a CT acquisition. Criteria used for interpretation are inconsistent, especially for planar imaging.
Source: Journal of Nuclear Medicine - August 3, 2015 Category: Nuclear Medicine Authors: Le Roux, P.-Y., Pelletier-Galarneau, M., De Laroche, R., Hofman, M. S., Zuckier, L. S., Roach, P., Vuillez, J.-P., Hicks, R. J., Le Gal, G., Salaun, P.-Y. Tags: Clinical Investigations Source Type: research

Nuclear medicine in pediatric refractory epilepsy
Abstract The nuclear medicine procedures 99mTc-ECD SPECT and 18F-FDG PET play an important diagnostic role in children with refractory seizures. In select patients, surgical removal of epileptogenic cortex is a therapeutic option. Magnetic resonance imaging (MRI) is the principal imaging method used to identify which patients would benefit from the surgery. However, there are cases when MRI does not detect an abnormality (MRI-negative epilepsy). Under these, and other circumstances, functional nuclear medicine studies are helpful in the workup of these patients. A combination of nuclear medicine procedures with MR...
Source: Clinical and Translational Imaging - March 21, 2016 Category: Radiology Source Type: research

Nuclear medicine: workplace monitoring and internal occupational exposure during a ventilation/perfusion single-photon emission tomography.
Abstract The administration of 99mTc-HDP to diagnose pulmonary thromboembolisms leads to the presence of 99mTc in the environment of a nuclear medicine department, which could pose a potential risk of internal contamination to medical staff. Therefore, air samples from the administration room, gamma camera room and corridor of such a department were taken for the purpose of performing a workplace monitoring program of the medical centre under study, with maximum activity values of 640 ± 30 kBq/m3, 1.5 ± 0.1 kBq/m3 and 54 ± 3 kBq/m3, respectively, being obtained. These results correspond to commit...
Source: Radiation and Environmental Biophysics - May 27, 2019 Category: Physics Authors: Martínez J, Baciu T, Artigues M, Danús M, Peñalver A, Aguilar C, Borrull F Tags: Radiat Environ Biophys Source Type: research

Prospective randomized controlled trial study of Luofengning granule in the treatment of unstable angina
Discussion: The results of this trial will provide compelling evidence of the efficacy and safety of LFN-G for treatment of UA and preliminarily reveal the potential mechanism of how LFN-G acts. Finally, it will widen treatment options for patients with UA.
Source: Medicine - May 1, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients: A Multicenter Study
Conclusion: In this population of COVID-19 patients assessed with lung scintigraphy, PE could confidently be excluded without the ventilation imaging in only 57% of patients. Ventilation imaging was required to confidently rule out PE in 31% of patients. Overall, the prevalence of PE was low (12%).
Source: Journal of Nuclear Medicine - June 30, 2022 Category: Nuclear Medicine Authors: Roux, P.-Y. L., Bonnefoy, P.-B., Bahloul, A., Denizot, B., Barres, B., Moreau-Triby, C., Girma, A., Pallardy, A., Ceyrat, Q., Sarda-Mantel, L., Razzouk-Cadet, M., Zsigmond, R., Florent, C., Karcher, G., Salaun, P.-Y. Tags: Clinical Investigations Source Type: research

IJERPH, Vol. 20, Pages 5206: Impact of the Frequency and Type of Procedures Performed in Nuclear Medicine Units on the Expected Radiological Hazard
ta Pawlus Nuclear medicine procedures play an important role in medical diagnostics and therapy. They are related to the use of ionizing radiation, which affects the radiological exposure of all of the persons involved in their performance. The goal of the study was to estimate the doses associated with the performance of various nuclear medicine procedures in order to optimize workload management. The analysis was performed for 158 myocardial perfusion scintigraphy procedures, 24 bone scintigraphies, 9 thyroid scintigraphies (6 with use of 131I and 3 with 99mTc), 5 parathyroid glands and 5 renal scintigraphies. In thi...
Source: International Journal of Environmental Research and Public Health - March 15, 2023 Category: Environmental Health Authors: Katarzyna Matusiak Justyna Wolna Aleksandra Jung Leszek Sadowski Jolanta Pawlus Tags: Article Source Type: research

Comparison of 4-Dimensional Computed Tomography Ventilation With Nuclear Medicine Ventilation-Perfusion Imaging: A Clinical Validation Study
Conclusions: The current work compared 4DCT with VQ-based ventilation using clinically relevant global metrics and radiologist observations. We found good agreement between the radiologist's assessment of the 4DCT and VQ-ventilation images as well as the percent ventilation in each lung. The agreement lessened when the data were analyzed on a regional level. Our study presents an important step for the integration of 4DCT-ventilation into thoracic clinical practice.
Source: International Journal of Radiation Oncology * Biology * Physics - April 10, 2014 Category: Radiology Authors: Yevgeniy Vinogradskiy, Phillip J. Koo, Richard Castillo, Edward Castillo, Thomas Guerrero, Laurie E. Gaspar, Moyed Miften, Brian D. Kavanagh Tags: Physics Contributions Source Type: research

Safety of ventilation/perfusion single photon emission computed tomography for pulmonary embolism diagnosis
Conclusion A diagnostic management including V/Q SPECT interpreted with a diagnostic cut-off of “one segmental or two subsegmental mismatches” appears safe to exclude PE.
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 25, 2014 Category: Radiology Source Type: research

Editorial: Role of Mesenchymal Stem Cells (MSCs) in Regenerative Medicine and Cell Based Therapies.
Abstract Stem cell treatment or therapy is gaining interest as future medicine to treat several dreadful diseases/disorders. Especially mesenchymal stem cells (MSCs) derived from both embryonic and adult cell sources have shown tremendous impact on improving human health. These MSCs have evolved into intensely studied research subjects and clearly collected a great deal of experimental data in the past decade. Even after all these years, research on MSCs still remains a hot and happening area with lot many questions to be answered. In this direction, in our special issue we discussed the safety issue of MSCs as al...
Source: Current Stem Cell Research and Therapy - October 19, 2014 Category: Stem Cells Authors: Mekala NK Tags: Curr Stem Cell Res Ther Source Type: research

Use of Radiopharmaceuticals in Diagnostic Nuclear Medicine in the United States: 1960–2010
Abstract: To reconstruct reliable nuclear medicine-related occupational radiation doses or doses received as patients from radiopharmaceuticals over the last five decades, the authors assessed which radiopharmaceuticals were used in different time periods, their relative frequency of use, and typical values of the administered activity. This paper presents data on the changing patterns of clinical use of radiopharmaceuticals and documents the range of activity administered to adult patients undergoing diagnostic nuclear medicine procedures in the U.S. between 1960 and 2010. Data are presented for 15 diagnostic imaging proc...
Source: Health Physics - March 27, 2015 Category: Radiology Tags: Papers Source Type: research

Imaging correlates of a pediatric case with 3 kidneys
Conclusions Supernumerary kidneys are often accompanied by other urinary tract anomalies with resultant pathologies such as hydronephrosis, as in our case. Management depends on symptoms, function, and anatomy of the renal moieties [7]. Urology intervention was performed in this case to help preserve the left renal function. RESEARCH SUPPORT:
Source: Journal of Nuclear Medicine - May 23, 2016 Category: Nuclear Medicine Authors: Doan, J., Hiller, J., Charles, L. Tags: MTA I: Educational Exhibits Posters Source Type: research

Maximizing reimbursement, maintaining quality, decreasing exposure and more with myocardial perfusion imaging: A literature review
Conclusions -
Source: Journal of Nuclear Medicine - May 23, 2016 Category: Nuclear Medicine Authors: Clayton, A., Slade, J. Tags: Technologist Student Papers II Source Type: research

Pet Radiopharmaceuticals for Personalized Medicine.
Abstract Recent advances in the self-shielded cyclotrons, improved targets, video-monitored hot cells design, and automated PET radiopharmaceutical (RPs) synthesis modules, utilizing computer-controlled graphic user interphase (GUI) has revolutionized PET molecular imaging technology for basic biomedical research and theranostics to accomplish the ultimate goal of evidence-based personalized medicine. Particularly, [18F]HX4: (3-[18F]fluoro-2-(4-((2-nitro-1Himidazol-1-yl)methyl)-1H-1,2,3,-triazol-1-yl)-propan-1-ol), 18F-FAZA: 1-(5-[18F]Fluoro-5-deoxy-α-D-arabinofuranosyl)-2-nitroimidazole, and 18F-FMSIO: 18F-Ffluo...
Source: Current Drug Targets - July 18, 2016 Category: Drugs & Pharmacology Authors: Sharma SK Tags: Curr Drug Targets Source Type: research

A new era for Nuclear Medicine neuroimaging in Spain: Where do we start from?
Conclusions These results reflect the clinical activity of 2013 and first quarter of 2014. The main indications of the studies were cognitive impairment and movement disorders. Variability in the evaluation of the studies is among the challenges that will be faced in the coming years.
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - June 28, 2017 Category: Nuclear Medicine Source Type: research

Management of severe traumatic brain injury (first 24hours)
Publication date: Available online 27 December 2017 Source:Anaesthesia Critical Care & Pain Medicine Author(s): Thomas Geeraerts, Lionel Velly, Lamine Abdennour, Karim Asehnoune, Gérard Audibert, Pierre Bouzat, Nicolas Bruder, Romain Carrillon, Vincent Cottenceau, François Cotton, Sonia Courtil-Teyssedre, Claire Dahyot-Fizelier, Frédéric Dailler, Jean-Stéphane David, Nicolas Engrand, Dominique Fletcher, Gilles Francony, Laurent Gergelé, Carole Ichai, Étienne Javouhey, Pierre-Etienne Leblanc, Thomas Lieutaud, Philippe Meyer, Sébastien Mirek, Gilles Orliaguet, François Proust, Hervé Quintard, Catherine Rac...
Source: Anaesthesia, Critical Care and Pain Medicine - February 9, 2018 Category: Anesthesiology Source Type: research