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Humoral Immunity in Arsenic-Exposed Children in Rural Bangladesh: Total Immunoglobulins and Vaccine-Specific Antibodies
Conclusions:
Arsenic exposure increased tIgG and tIgE in plasma, and tended to decrease mumps-specific IgG in children at 9 years of age. https://doi.org/10.1289/EHP318
Received: 09 April 2016
Revised: 09 October 2016
Accepted: 24 October 2016
Published: 14 June 2017
Address correspondence to R. Raqib, Immunobiology, Nutrition and Toxicology Laboratory, Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Mohakhali, Dhaka-1212, Bangladesh. Telephone: 880-2-9827068. E-mail: rubhana@icddrb.org
Supplemental Material is available online (https://doi.org/10.1289/EHP318).
The authors declare they have n...
Source: EHP Research - June 15, 2017 Category: Environmental Health Authors: Karla Gonzalez Tags: Research Source Type: research
What is the Interval For Non-simultaneous Administration of Live Virus Vaccines?
Discussion
Vaccines are a mainstay of infectious disease prevention and health promotion. Infants, children and adults benefit from vaccines the most when they are given on the recommended schedules. However there are times when this is not possible as children come to the physician a little early, or a little late, or had unavailable records and so received addition vaccine, etc. There are many questions that arise because of these timing issues such as the one above.
Standard vaccine schedules can be reviewed here.
Commonly administered vaccines includes:
Live-attenuated vaccines
Cholera
Measles, mumps, rubella (MMR ...
Source: PediatricEducation.org - July 9, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Hong Kong Institute of Allergy and Hong Kong Society for Paediatric Immunology Allergy & Infectious Diseases joint consensus statement 2018 on vaccination in egg-allergic patients.
Hong Kong Institute of Allergy and Hong Kong Society for Paediatric Immunology Allergy & Infectious Diseases joint consensus statement 2018 on vaccination in egg-allergic patients.
Hong Kong Med J. 2018 Oct;24(5):527-531
Authors: Chua GT, Li PH, Ho MH, Lai E, Ngai V, Yau FY, Kwan MY, Leung TF, Lee TH
Abstract
Vaccination of egg-allergic individuals has been a historical concern, particularly for influenza and measles-mumps-rubella-varicella vaccines that are developed in chicken egg embryos or chicken cell fibroblasts. The egg proteins in these vaccines were believed to trigger an immediate allerg...
Source: Hong Kong Med J - October 1, 2018 Category: General Medicine Authors: Chua GT, Li PH, Ho MH, Lai E, Ngai V, Yau FY, Kwan MY, Leung TF, Lee TH Tags: Hong Kong Med J Source Type: research
Efficient Gene Transduction and Reprogramming of Hematopoietic Cells Including T-Cells By Using a Non-Integrating Measles Virus Vector
In this study, we developed a new non-integrating measles virus (MV) vector-based delivery system with F deletion to eliminate cell membrane fusion-associated cytotoxicity. MV vectors transduced genes through MV receptors including CD46 and signaling lymphocyte activation molecule (CD150/SLAM). First, we examined transduction efficiencies of MV vectors and SV vectors in hematopoietic cells by using GFP expression vectors (MV-Gs and SV-Gs). Compared to SV-Gs, our MV-Gs allowed more efficient gene transfer into most hematopoietic cell type including T (3-fold) and B cells (7-fold) (Fig. 1). Furthermore, at the same multiplic...
Source: Blood - November 21, 2018 Category: Hematology Authors: Liao, J., Soda, Y., Sugawara, A., Miura, Y., Hiramoto, T., Tahara, M., Takishima, Y., Hirose, L., Hijikata, Y., Miyamoto, S., Takeda, M., Tani, K. Tags: 801. Gene Therapy and Transfer: Poster II Source Type: research
Some Anti-Vaxxers Aren ’t Getting Their Pets Vaccinated. Here’s Why That’s So Dangerous
Dogs can’t get autism, and even if they could, vaccines couldn’t cause it. Period. But some anti-vaxxers are increasingly making the same unfounded claims about pets and vaccines they’ve been repeating about children and vaccines for the past 20 years: that vaccines are unnecessary, dangerous and that they can cause a form of (canine) autism, along with other diseases. Just as with kids, that may be driving down pet vaccination rates. And the movement, while niche, shows no sign of stopping; in some states in the U.S., anti-vax activists have recently agitated to make state laws about mandatory pet vaccin...
Source: TIME: Health - March 8, 2019 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized onetime Pets Source Type: news
Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies
Conclusions
Apart West Nile virus (78), thousands of congenital microcephaly cases, fetal brain tissue damage and neurological syndromes have been associated with ZIKV infection. Unfortunately, the epidemics of this mosquito born, and a relative stable virus is on a rise. Although congenital microcephaly is a rare disorder however, due to lack of standardized diagnostic test facilities, the incidence in the geographically widespread ZIKV epidemic regions is higher. Animals studies showed that ZIKV is a neurotropic virus. It directly targets the developing embryonic brain cells by inducing apoptosis, cell-cycle arrest, and...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research
Insights Into Dolphins' Immunology: Immuno-Phenotypic Study on Mediterranean and Atlantic Stranded Cetaceans
This study was aimed at implementing the knowledge on the immune response in cetaceans stranded along the Italian coastline to provide a baseline useful for assessing the immune status of bottlenose (Tursiops truncatus) and striped (Stenella coeruleoalba) dolphins. In particular, since the Mediterranean Sea is considered a heavily polluted basin, a comparison with animals living in open waters such as the Atlantic Ocean was made. Formalin-fixed, paraffin-embedded spleen, thymus, and lymph node tissues from 16 animals stranded along Italian and 11 cetaceans from the Canary Island shores were sampled within 48 h from death. ...
Source: Frontiers in Immunology - April 23, 2019 Category: Allergy & Immunology Source Type: research
A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including Pertactin Deficient Strains
This study was conducted in accordance with the recommendations and guidelines and under licenses approved by the Health Products Regulatory Authority of Ireland and Argentina. The protocol was approved by the Trinity College Dublin Animal Research Ethics Committee and the Ethical Committee for Animal Experiments of the Faculty of Science at La Plata National University (Argentina, approval number 004-06-15 and 003-06-15).
Author Contributions
DH and KM planned the study, interpreted data, and wrote the manuscript. MZ and MW planned the study, interpreted data, and edited the figures and manuscript. FC, EB, GM, and AM pe...
Source: Frontiers in cellular and infection microbiology - April 25, 2019 Category: Microbiology Source Type: research
Should You Get a Measles Booster Shot? Here ’s What Experts Say
Unvaccinated individuals have been the focus of attention during this year’s measles outbreaks. A record 704 cases of the illness have been confirmed in 22 states so far in 2019, and the CDC says the majority of those diagnoses have been in unvaccinated people. Health officials have repeatedly warned nearly everyone to get the shot if they haven’t already — sometimes threatening fines for those who refuse.
“Over 90% of the measles cases that have occurred in the U.S. have occurred in unvaccinated persons,” says Dr. William Schaffner, a professor of preventive medicine and infectious diseases a...
Source: TIME: Health - April 29, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized public health Source Type: news
‘They’re Chipping Away.’ Inside the Grassroots Effort to Fight Mandatory Vaccines
Christina Hildebrand went down a rabbit hole and emerged at the statehouse in Sacramento.
That’s how she describes it–going down a rabbit hole–and in her case it happened 14 years ago, when she was pregnant with her first child. In a world filled with chemicals and toxins, processed foods and GMOs, she decided her baby would be brought up as naturally and chemical-free as possible. It was when she was researching how best to achieve that goal that she bumped into vaccines.
That was a bad time to begin thinking about such things. The fraudulent 1998 paper by British physician Andrew Wakefield ostensibly li...
Source: TIME: Health - June 13, 2019 Category: Consumer Health News Authors: Jeffrey Kluger/Sacramento Tags: Uncategorized vaccines Source Type: news
Travel vaccinations.
This article provides information on these and other travel vaccinations against hepatitis A, typhoid fever, rabies, Japanese encephalitis and cholera.Yellow fever endemic areas are located in Africa and in South America; there is no yellow fever in Asia. The meningococcal vaccine (A, C, W, Y) is required for pilgrims to Saudi Arabia. Additionally, it is recommended for travellers visiting the African "meningitis belt" during the dry season. A polio booster is required for countries with endemic wild-type polio virus (WPV) or circulating vaccine derived poliovirus (cVDPV).Hepatitis A is a common vaccine-preventable infect...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 3, 2019 Category: International Medicine & Public Health Authors: Rothe C, Boecken G, Ständiger Ausschuss Reisemedizin (StAR) der Deutschen Gesellschaft für Tropenmedizin und Globale Gesundheit (DTG) Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research
How Long Will the Coronavirus Outbreak Last? Experts Are Scrambling to Find Out
As a novel coronavirus known as 2019-nCoV continues to spread throughout China and to countries across the world, the big question is: How long will the outbreak last—and how bad will it get?
While some doctors have made predictions and outbreaks of similar coronaviruses like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) provide clues, the short, if unsatisfying, answer is that no one is exactly sure.
“There is no scientist nor sage on the planet that will tell you when the peak of this epidemic will occur,” said Dr. Michael Ryan, executive director of the World Heal...
Source: TIME: Health - January 30, 2020 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized 2019-nCoV Infectious Disease Source Type: news
Millions of Children Are at Risk for Measles as Coronavirus Fears Halt Vaccines
U.N. and global health experts warned that poor countries around the world were having to stop mass immunization programs to reduce the risk of spreading Covid-19.
Source: NYT Health - April 14, 2020 Category: Consumer Health News Authors: Jan Hoffman Tags: Measles Coronavirus (2019-nCoV) Epidemics Vaccination and Immunization Medicine and Health Children and Childhood Babies and Infants Preventive Medicine Source Type: news
There Isn ’t a COVID-19 Vaccine Yet. But Some Are Already Skeptical About It
Amid the American flags, “Make America Great Again” hats and “freedom is essential” posters appearing at recent protests against coronavirus lockdowns in Sacramento, Calif., another familiar slogan has materialized: “We do not consent.” It’s long been a popular rallying cry among antivaccine activists, who claim without evidence that vaccines cause autism or other conditions. As the COVID-19 pandemic rages on, those activists have become intertwined with demonstrators who want businesses to reopen despite public health experts’ warnings.
Offline, the “anti-vaxxers”...
Source: TIME: Health - May 18, 2020 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized COVID-19 Source Type: news
