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Automatic characterization of myocardial perfusion imaging polar maps employing deep learning and data augmentation.
CONCLUSION: The proposed deep learning model with data augmentation techniques performed better than the conventional semi-quantitative polar map analysis and competed with doctor's expertise in this particular patient cohort and image set. The model could potentially serve as an assisting tool to support interpretation of MPI studies or could be used for teaching purposes. PMID: 32716403 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Assessment of ejection fraction and heart perfusion using myocardial perfusion single-photon emission computed tomography in Finland and Estonia: a multicenter phantom study
Conclusion On average, the EF and heart perfusion were accurately estimated by SPECT/CT, but high errors could be produced if the acquisition and analysis routines were poorly optimized. Eight of the 21 participants altered their imaging protocol after this quality control tour.
Source: Nuclear Medicine Communications - August 14, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Lacunar stroke as a very late complication of radiotherapy: value of nuclear medicine techniques.
CONCLUSIONS: The reappearance of neurological symptoms years after radiotherapy of a brain neoplasm poses a diagnostic dilemma. Current diagnostic techniques are very accurate but present false positives. The various nuclear medicine techniques, in particular PET-CT 11C-methionine, are a diagnostic aid. With the presentation of this case we intend to draw attention to one of the late complications of radiation therapy and the various differential diagnoses. Diagnostic and therapeutic advances have increased the life expectancy of cancer patients, so these late complications are expected to be more frequent. PMID: 3331...
Source: Revista de Neurologia - December 16, 2020 Category: Neurology Authors: Ortega-Valín F, Jiménez-Bonilla JF, García-Hernández A, Rodríguez-Rodriguez E, Sánchez-Salmón E Tags: Rev Neurol Source Type: research

Implementation of a Lung Perfusion Only Imaging Protocol with SPECT or SPECT/CT in a Major Academic University Hospital Healthcare System in Adaption to the COVID-19 Pandemic.
Conclusions: The COVID-19 pandemic has forced medical institutions and health care systems all over the world to adapt to a rapidly changing environment with the challenge to deliver high quality health care while minimizing risk to staff and patients alike. This has presented a unique problem requiring both flexibility and innovativeness. Furthermore, there are the logistical challenges in policy implementation which are proportionally increased the larger the system is. Aerosol-generating procedures, such as ventilation scanning, inherently increase the risk of virus spread. The incorporation of SPECT or SPECT/CT with Tc...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Wojtylak, P., Jones, R., Mehta, L., Avril, N., Kardan, A. Tags: Integral Role of imaging in the Management of Covid-19 Patients Source Type: research

Hybrid perfusion SPECT-CT can be a good alternative for traditional V/Q scan.
155Objectives: 1. To recognize the impact of the COVID-19 pandemic to imaging in Nuclear Medicine. 2. To understand the importance of the V/Q study during a pandemic and how to modify the study for the safety of patients and technologists while still providing quality images. 3. Understanding the benefits of perfusion SPECT/CT studies compared to a traditional V/Q study. 4. To provide examples of both positive and negative studies for pulmonary embolism with SPECT/CT. Pulmonary embolism (PE) has been and continues to be a challenging diagnosis especially in the new era of the COVID-19 global pandemic. Challenges of COVID-1...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: TEMSAH, P., Alassi, A., Muzaffar, R., Osman, M. Tags: Technologist Student Oral Session I Source Type: research

Evaluating the necessity of ventilation lung imaging, based on perfusion only imaging during the COVID-19 pandemic.
Conclusions: This study showed that in 80.56% of patients, ventilation images were not required to indicate a very low or low probability of pulmonary embolism. In 19.44% of patients, perfusion only images indicated either intermediate or high probability of a pulmonary embolism. WIthout the aerosol generating procedure limits during the COVID-19 pandemic, ventilation scans could have been obtained after the perfusion images for additional information in this moderate or high probability group. This study indicates that performing ventilation imaging on every patient may not be beneficial to the majority of patients. Perfo...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Brickley, L., Hampton, S., Voslar, A. Tags: Technologist Student Oral Session I Source Type: research

Perfusion Only Scans with and without SPECT/CT in the Era of COVID-19
Conclusion: Perfusion-only studies performed with the addition of SPECT/CT increases the overall sensitivity for detecting pulmonary embolism, with excellent negative predictive value. Given the tradeoff of detecting more false negatives for more false positives, and the cost of performing SPECT/CT, the utilization of SPECT/CT may be selectively limited to higher-risk patients with high-pretest probability or equivocal planar imaging. These findings suggest a nuanced role for SPECT-CT during the COVID-19 era where the ability to perform concurrent ventilation scans is limited. Figure 1. Planar perfusion images in the anter...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Zhang, R., Moradi, F., Mari Aparici, C., Davidzon, G., Nguyen, J., Iagaru, A., Franc, B. Tags: Infectious Disease/Pulmonary/Outcomes Source Type: research

Considerations about Ventilation and Perfusion Imaging for the Diagnosis of Pulmonary Embolism During the COVID-19 Pandemic
2009Introduction: A new type of coronavirus, SARS-CoV-2 (Covid 19), was identified in December 2019 in China. The resultant world-wide pandemic turned into one of the biggest challenges in the recent history of medicine. The virus is transmitted via respiratory droplets during close unprotected contact between individuals. Patients with COVID-19 infection are at increased risk of developing pulmonary embolism (PE), which may occur in up to one-third of COVID-19 patients requiring ICU admission. Ventilation Perfusion (V/Q) pulmonary scintigraphy can play a role in the management of patients hospitalized for COVID-19 infecti...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Bural, G., Torigian, D., Alavi, A. Tags: General Clinical Specialties Source Type: research

Imaging Biomarkers of Alzheimers disease: The crucial role of Molecular Imaging
2019Objectives: 1. To present the value of imaging biomarkers in Alzheimer’s disease (AD). 2. To overview the current status of neuroimaging with SPECT and PET in AD. 3. To demonstrate the role of different radioligands in the imaging of the pathophysiology and other molecular processes in AD. Abstract Body: Increase in aging population is associated with increased number of patients with complaints of cognitive impairment. The most prevalent cause of dementia in the elderly individuals is AD. In AD, there is abnormal build-up of two proteins, amyloid and tau. Amyloid accumulates as plaques and tau as neurofibrillary...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Koutsikos, J., Velidaki, A. Tags: Neurosciences Source Type: research

KSNM60 in Cardiology: Regrowth After a Long Pause
AbstractThe Korean Society of Nuclear Medicine (KSNM) is celebrating its 60th anniversary in honor of the nuclear medicine professionals who have dedicated their efforts towards research, academics, and the more comprehensive clinical applications and uses of nuclear imaging modalities. Nuclear cardiology in Korea was at its prime time in the 1990s, but its growth was interrupted by a long pause. Despite the academic and practical challenges, nuclear cardiology in Korea now meets the second leap, attributed to the growth in molecular imaging tailored for many non-coronary diseases and the genuine values of nuclear myocardi...
Source: Nuclear Medicine and Molecular Imaging - June 8, 2021 Category: Nuclear Medicine Source Type: research

Deep learning-based denoising of low-dose SPECT myocardial perfusion images: quantitative assessment and clinical performance
CONCLUSION: The noise was effectively suppressed by the proposed network, and the predicted standard-dose images were comparable to reference standard-dose images at half- and quarter-dose levels. However, recovery of the underlying signals/information in low-dose images beyond a quarter of the standard dose would not be feasible (due to very poor signal-to-noise ratio) which will adversely affect the clinical interpretation of the resulting images.PMID:34778929 | DOI:10.1007/s00259-021-05614-7
Source: Molecular Medicine - November 15, 2021 Category: Molecular Biology Authors: Narges Aghakhan Olia Alireza Kamali-Asl Sanaz Hariri Tabrizi Parham Geramifar Peyman Sheikhzadeh Saeed Farzanefar Hossein Arabi Habib Zaidi Source Type: research

60 Years of Achievements by KSNM in Neuroimaging Research
AbstractNuclear medicine neuroimaging is able to show functional and molecular biologic abnormalities in various neuropsychiatric diseases. Therefore, it has played important roles in the clinical diagnosis and in research on the normal and pathological states of the brain. More than 400 outstanding studies have been conducted by Korean researchers over the past 60  years. In the 1990s, when multiheaded single-photon emission computed tomography (SPECT) scanners were first introduced in South Korea, stroke research using brain perfusion SPECT was conducted. With the spread of positron emission tomography (PET) scanners in...
Source: Nuclear Medicine and Molecular Imaging - January 15, 2022 Category: Nuclear Medicine Source Type: research