Filtered By:
Therapy: Cancer Therapy

This page shows you your search results in order of relevance. This is page number 18.

Order by Relevance | Date

Total 4168 results found since Jan 2013.

Astragaloside Ⅳ reduces the expression level of P‑glycoprotein in multidrug‑resistant human hepatic cancer cell lines.
In conclusion, the results of the present study indicated that ASIV reverses the drug resistance of Bel‑7402/FU cells by downregulating the expression of mdr1. ASIV may represent a potent modulator of P‑gp‑mediated MDR in hepatic cancer therapy. PMID: 24676670 [PubMed - as supplied by publisher]
Source: Molecular Medicine - March 27, 2014 Category: Molecular Biology Authors: Wang PP, Xu DJ, Huang C, Wang WP, Xu WK Tags: Mol Med Rep Source Type: research

Cancer therapy resistance: chasing epigenetics
Nature Medicine 20, 340 (2014). doi:10.1038/nm.3528
Source: Nature Medicine - April 7, 2014 Category: Journals (General) Tags: Community Corner Source Type: research

Content, quality, and readability of website information on dental care for patients with cancer
Conclusions: Websites addressing dental care for patients with cancer are broad in content yet are limited in quality and are written at difficult reading levels.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 10, 2014 Category: ENT & OMF Authors: Lauren L. Patton, Stephanie F. George, Robert P. Hollowell Tags: Oral Medicine Source Type: research

Total darkness at night is key to success of breast cancer therapy -- Tulane study
(Tulane University) Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School of Medicine cancer researchers.
Source: EurekAlert! - Medicine and Health - July 25, 2014 Category: Global & Universal Source Type: news

Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-kappaB pathway
Conclusions: Our study has provided the first direct evidence that ZJW reverses drug-resistance in human colorectal cancer by blocking the PI3K/Akt/NF-kappaB signaling pathway, and could be considered as a useful drug for cancer therapy.
Source: BMC Complementary and Alternative Medicine - August 1, 2014 Category: Complementary Medicine Authors: Hua SuiShu-Fang PanXiao-Lan ShiBao-Hui JinXuan LiuLi-Hong ZhouFeng-Gang HouWen-Hai WangXiao-Ling FuJian-Lin RenHui-Rong ZhuQi Li Source Type: research

Characteristics of Cancer Patients Presenting to an Integrative Medicine Practice-Based Research Network
Conclusions: Demographic characteristics, depression scores, perceived stress scores, and reasons for seeking integrative cancer care were not significantly different between cancer patients and noncancer patients. Perceived stress may be an important indicator of QOL. The association of perceived stress, depression and pain with seeking spirituality suggests that providing IM interventions, such as effective stress management techniques and pastoral or spiritual counseling, may be helpful to patients living with cancer.
Source: Integrative Cancer Therapies - August 11, 2014 Category: Cancer & Oncology Authors: Edman, J. S., Roberts, R. S., Dusek, J. A., Dolor, R., Wolever, R. Q., Abrams, D. I. Tags: Articles Source Type: research

Telomeres and telomerase: Understanding basic structure and potential new therapeutic strategies targeting it in the treatment of cancer
This article provides a basic understanding of telomere and telomerase in cancer and summarizes various potential therapeutic approaches used for strategic targeting of telomerase enzyme. Medline, Medscape, EMBASE, Cochrane database, Scopus and clinicaltrials.gov were searched using terms like "telomeres", "telomerase" and "targeted cancer therapy". Journal articles published from 2005 to 2013 describing telomerase-based cancer therapy were screened.
Source: Journal of Postgraduate Medicine - August 14, 2014 Category: Internal Medicine Authors: K Sekhri Source Type: research

Relationship between preparation of cells for therapy and cell quality using artificial neural network analysis
Conclusion CD9 surface marker loss was the most sensitive indicator of the effects of shear stress followed by loss of membrane integrity and then HLA A-C, while CD147 remained unaffected by shear stress or even prone to increase. Also greater stability of cell surface marker presence was noted for cells generated at greater passage numbers or generation numbers or for reduction in hold time in formulation buffer.
Source: Artificial Intelligence in Medicine - October 12, 2014 Category: Bioinformatics Source Type: research

Synthetic Lethality and Cancer Therapy: Lessons Learned from the Development of PARP Inhibitors.
Abstract The genetic concept of synthetic lethality, in which the combination or synthesis of mutations in multiple genes results in cell death, provides a framework to design novel therapeutic approaches to cancer. Already there are promising indications, from clinical trials exploiting this concept by using poly(ADP-ribose) polymerase (PARP) inhibitors in patients with germline BRCA1 or BRCA2 gene mutations, that this approach could be beneficial. Wediscuss the biological rationale for BRCA-PARP synthetic lethality, how the synthetic lethal approach is being assessed in the clinic, and how mechanisms of resistan...
Source: Annual Review of Medicine - October 17, 2014 Category: Journals (General) Authors: Lord CJ, Tutt AN, Ashworth A Tags: Annu Rev Med Source Type: research

Tibetan Medicine for Cancer: An Overview and Review of Case Studies
Conclusions: This limited case review found TM to be safe and have positive effects on quality of life and disease regression and remission in patients with cancer and blood disorders. Further exploration and investigation using rigorous methods is warranted.
Source: Integrative Cancer Therapies - October 29, 2014 Category: Cancer & Oncology Authors: Bauer-Wu, S., Lhundup, T., Tidwell, T., Lhadon, T., Ozawa-de Silva, C., Dolma, J., Dorjee, P., Neshar, D. R., Sangmo, R., Yeshi, T. Tags: Articles Source Type: research

Screening of Stat3 inhibitory effects of Korean herbal medicines in the A549 human lung cancer cell line
Conclusion Many medicinal herbs traditionally used in Korea contain Stat3 activity-suppressing substances. Because of the therapeutic impact of Stat3 inhibition, these results could be useful when developing novel cancer therapeutics from medicinal herbs.
Source: Integrative Medicine Research - October 12, 2014 Category: Complementary Medicine Source Type: research

Low doses of ethanolic extract of Boldo (Peumus boldus) can ameliorate toxicity generated by cisplatin in normal liver cells of mice in vivo and in WRL-68 cells in vitro, but not in cancer cells in vivo or in vitro
Conclusion Results indicated that a low dose of BE could be used beneficially in combination with cisplatin to reduce its toxicity without hampering cisplatin's anticancer effect. These findings signify a potential future use of BE in cancer therapy.
Source: Journal of Integrative Medicine - November 3, 2014 Category: Complementary Medicine Source Type: research

Use of diagnostic and therapeutic biomarkers in personalized oncology based on adult T-cell leukemia/lymphoma research
Publication date: July 2013 Source:Personalized Medicine Universe, Volume 2 Author(s): Hiroo Hasegawa , Shimeru Kamihira Human T-lymphotropic virus type 1 (HTLV-1) infection is linked to a spectrum of diverse diseases, including adult T-cell leukemia/lymphoma (ATLL) and the chronic neuromyelopathy tropical spastic paraparesis or HTLV-1 associated myelopathy (TSP/HAM). ATLL is a neoplasm of mature CD4+ T-cell origin known to be resistant to standard anti-cancer therapies. Based on ATLL research performed in our laboratory as well as other reports, we discuss diagnostic, predictive, and pharmacological biomarkers for compa...
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research

Epigenetics in cancer and inflammation
Conclusion Elucidating DNA methylation is important for understanding molecular biology and human disease. Further studies of epigenetics will contribute to applications for diagnosis and therapy in human disease.
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research

High-dose intravenous vitamin C improves quality of life in cancer patients
Conclusions IVC can safely improve the QOL of cancer patients. These results warrant the conduct of prospective comparative studies to evaluate the usefulness of IVC for patients with advanced cancer.
Source: Personalized Medicine Universe - November 6, 2014 Category: Drugs & Pharmacology Source Type: research